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Autor:
Virginia Paton, Gracie Lieberman, Melody A. Cobleigh, Debasish Tripathy, Nicholas J. Robert, Charles L. Vogel, Louis Fehrenbacher, Janet M. Wolter, Steven Shak, Susy Scholl, Dennis J. Slamon
Publikováno v:
Journal of Clinical Oncology. 41:1501-1510
PURPOSE Overexpression of the HER2 protein occurs in 25% to 30% of human breast cancers and leads to a particularly aggressive form of the disease. Efficacy and safety of recombinant humanized anti-HER2 monoclonal antibody as a single agent was evalu
Autor:
Alan Nichol, Elisa K. Chan, Stephen Chia, Caroline Lohrisch, Nafisha Lalani, Lovedeep Gondara, Karen A. Gelmon, Daegan Sit, Eric Tran, Caroline Speers
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 112:861-869
Randomized clinical trials have shown that regional nodal irradiation (RNI) in patients with unselected N1 breast cancer improves breast cancer-specific survival. However, the benefit of RNI in women with biologically low-risk N1 breast cancer is unc
Autor:
C. Meyer, Y. Fouché, Emmanuel Chamorey, M. Dejode, C. Bailleux, J. Haudebourg, Renaud Schiappa, Y. Delpech, Emmanuel Barranger
Publikováno v:
Clinical Breast Cancer. 22:121-126
Background Delays in initiating adjuvant chemotherapy after breast cancer surgery seems to have an impact on patients’ risk of relapse and their survival rate. The aim of this retrospective study was to identify factors delaying initiation of adjuv
Publikováno v:
International Journal of Cancer. 150:1156-1165
Previous studies have reported inconsistent findings concerning the impact of statin use on cancer prevention. This study examined the association between statin use and cancer incidence and mortality related to breast and gynecologic cancers in Sout
Publikováno v:
Cancer Medicine, Vol 10, Iss 23, Pp 8320-8327 (2021)
Cancer Medicine
Cancer Medicine
Background Minimally invasive breast biopsy (MIBB) is the standard of care for the diagnosis of breast cancer, with consensus guidelines suggesting MIBB goals of 90% of total biopsies. In a previous study of patients in the rural state of Vermont, US
Autor:
Larisa M. Haupt, Gabrielle Bradshaw, K.M. Taufiqul Arif, Rachel K. Okolicsanyi, Philippa H. Youl, Robert A. Smith, Thanh Tan Nguyen, Lyn R. Griffiths
Publikováno v:
Clinical Breast Cancer. 21:e694-e703
Introduction Breast cancer (BC), a heterogeneous disease, features microRNA-related single nucleotide polymorphisms (miRSNPs) as underlying factors of BC development, thus providing targets for novel diagnostic and therapeutic strategies. This study
Autor:
Lauren R. Teras, Siddhartha Yadav, Amy Trentham-Dietz, Dale P. Sandler, James M. Hodge, Elena Ma Martínez, Fergus J. Couch, Jack A. Taylor, Katie M. O'Brien, Alpa V. Patel, Christopher A. Haiman, Chunling Hu, Mia M. Gaudet, David E. Goldgar, Paul W. Auer, James V. Lacey, Nicholas J. Boddicker, Sara Lindström, Celine M. Vachon, Susan L. Neuhausen, Irene M. Ong, Kimberly A. Bertrand, Leslie Bernstein, Loic Le Marchand, Eric C. Polley, Janet E. Olson, Hongyan Huang, Christine B. Ambrosone, Tina Pesaran, Susan M. Domchek, Amal Yussuf, Nicole L. Larson, Rohan Gnanaolivu, Brian D. Carter, Song Yao, Steven N. Hart, Holly LaDuca, Rachid Karam, Jie Na, Chi Gao, Katherine L. Nathanson, Peter Kraft, Elizabeth C. Chao, Huiyan Ma, Jeffrey N. Weitzel, Julie R. Palmer, Christopher E. Scott, Charles Kooperberg, Jill S. Dolinsky, David J. Hunter, Elizabeth S. Burnside
Publikováno v:
J Clin Oncol
PURPOSE The prevalence of germline pathogenic variants (PVs) in established breast cancer predisposition genes in women in the general population over age 65 years is not well-defined. However, testing guidelines suggest that women diagnosed with bre
Autor:
Kee Seng Chia, Jingmei Li, Elaine Hsuen Lim, Peh Joo Ho, Zi Lin Lim, Wen Yee Chay, Mikael Hartman, Fuh Yong Wong
Publikováno v:
Cancer Medicine, Vol 10, Iss 22, Pp 8182-8191 (2021)
Cancer Medicine
Cancer Medicine
Background Breast cancer incidence is increasing in Asia. However, few women in Singapore attend routine mammography screening. We aim to identify women at high risk of breast cancer who will benefit most from regular screening using the Gail model a
Autor:
Shalin J. Shah, Emily Grade, Elizabeth S. Bloom, Wendy A. Woodward, Benjamin Smith, Isidora Arzu, Julius K. Weng, Xiudong Lei, Pamela J. Schlembach, Karen E. Hoffman, Gabriel N. Hortobagyi, Michael C. Stauder, Gregory M. Chronowski, Valerie Klairisa Reed, Thomas A. Buchholz, Welela Tereffe, Kelly K. Hunt, Eric A. Strom, George H. Perkins, Simona F. Shaitelman, Tomas Dvorak
Publikováno v:
Int J Radiat Oncol Biol Phys
PURPOSE: There are limited prospective data on predictors of patient-reported outcomes (PROs) after whole-breast irradiation (WBI) plus a boost. We sought to characterize longitudinal PROs and cosmesis in a randomized trial comparing conventionally f
Autor:
Gabrielle B. Rocque, Nicole E. Caston, Risha Gidwani, Andres Azuero, Jeffrey Franks, Monica S. Aswani, Courtney P. Williams
Publikováno v:
Breast Cancer Res Treat
PURPOSE: The extent to which evidence-based treatments are applied to populations not well represented in early stage breast cancer (EBC) trials remains unknown. This study evaluated treatment intensity for patients traditionally well represented, un