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Autor:
Astrid Louise Bjørn Bennedsen, Luyi Cai, Rune Petring Hasselager, Aysun Avci Özcan, Khadra Bashir Mohamed, Jens Ole Eriksen, Susanne Eiholm, Michael Bzorek, Anne-Marie Kanstrup Fiehn, Thomas Vauvert F. Hviid, Ismail Gögenur
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-19 (2022)
Bennedsen, A L B, Cai, L, Hasselager, R P, Özcan, A A, Mohamed, K B, Eriksen, J O, Eiholm, S, Bzorek, M, Fiehn, A-M K, Hviid, T V F & Gögenur, I 2022, ' An exploration of immunohistochemistry-based prognostic markers in patients undergoing curative resections for colon cancer ', BMC Cancer, vol. 22, 62 . https://doi.org/10.1186/s12885-022-09169-0
BMC Cancer
Bennedsen, A L B, Cai, L, Hasselager, R P, Özcan, A A, Mohamed, K B, Eriksen, J O, Eiholm, S, Bzorek, M, Fiehn, A-M K, Hviid, T V F & Gögenur, I 2022, ' An exploration of immunohistochemistry-based prognostic markers in patients undergoing curative resections for colon cancer ', BMC Cancer, vol. 22, 62 . https://doi.org/10.1186/s12885-022-09169-0
BMC Cancer
Background The immune system recognizes and destroys cancer cells. However, cancer cells develop mechanisms to avoid detection by expressing cell surface proteins. Specific tumour cell surface proteins (e.g. HLA-G, PD-L1, CDX2) either alone or in com
Autor:
Atanas Ignatov, Piotr Czapiewski, Thomas Kalinski, Willi Pieper, Norbert Nass, Johannes Haybaeck
Publikováno v:
Cancer Biomarkers. 32:161-173
BACKGROUND: Neuronatin (NNAT) determined by immunohistochemistry is a negative prognostic biomarker for breast cancer, independent of the major clinicopathological markers. OBJECTIVE: Here, we investigated whether NNAT is also a predictive biomarker
Autor:
Hiroshi Yagi, Yuki Masuda, Taizo Hibi, Naoto Kubota, Hidenori Ojima, Yoko Fujii-Nishimura, Yuta Abe, Masahiro Shinoda, Minoru Kitago, Yasushi Hasegawa, Go Oshima, Yuko Kitagawa, Shutaro Hori, Michiie Sakamoto, Yusuke Takemura
Publikováno v:
Cancer Medicine, Vol 10, Iss 16, Pp 5599-5613 (2021)
Cancer Medicine
Cancer Medicine
Gamma‐synuclein (SNCG) promotes invasive behavior and is reportedly a prognostic factor in a range of cancers. However, its role in biliary tract carcinoma (BTC) remains unknown. Consequently, we investigated the clinicopathological significance an
Publikováno v:
Breast Disease. 40:25-31
AIM OF THE STUDY: The microenvironment depicts the relationship between tumour cells and immune response, and every insight into stromal lymphocytes could contribute to explain their role and activity. E26 transformation specific-1 (ETS-1) is a trans
Publikováno v:
DNA and Cell Biology. 40:469-481
Bladder cancer (BC) is a common genitourinary malignancy worldwide. However, the molecular pathogenesis of BC remains unclear. The current study conducted bioinformatic analyses to discover key genes involved in BC progression. A total of 375 differe
Autor:
Roy Zvi Granit, Evandro de Azambuja, Giancarlo Pruneri, Amir Sonnenblick, Nadia Harbeck, Christos Sotiriou, Dominique Agbor-Tarh, Ibrahim Fahoum, Alvaro Moreno-Aspita, Miguel Izquierdo, Minetta C. Liu, Martine Piccart, Susanne Hultsch, Ghizlane Rouas
Publikováno v:
International journal of cancer
The JAK/STAT3 signaling pathway may be aberrantly activated and have various and conflicting roles in breast cancer. The current study explored prognostic implications of activated STAT3 in human epidermal growth factor receptor 2 (HER2)-positive pri
Autor:
Munetoshi Katagiri, Takeshi Naitoh, Hideaki Karasawa, Jun Sato, Michiaki Unno, Shimpei Maeda, Shinobu Ohnuma, Fuyuhiko Motoi, Shun Nakayama, Takashi Suzuki
Publikováno v:
Cancer Investigation. 38:214-227
Cripto-1 is a plasma membrane protein which is not expressed in adult tissue, but some tumors are accompanied by re-activation. We studied the clinical and biological significance of Cripto-1 in colorectal cancer. Cripto-1 was positive in 68 out of 1
Autor:
Yu-Feng Tian, Pei-Ling Hsieh, Ching-Chieh Yang, Chia-Lin Chou, Yow-Ling Shiue, Sung-Wei Lee, Wan-Shan Li, Cheng-Yi Lin
Publikováno v:
Oncology. 98:549-557
Background/Aim: A great proportion of patients with rectal cancer initially present with locally advanced disease and can potentially benefit from neoadjuvant concurrent chemoradiotherapy (CCRT) for downstaging before surgery. However, risk and clini
Autor:
Dongni Wang, Jing Shi, Jing Feng, Jiming Shen, Xu Han, Sha Shi, Yu Shi, Mingfang Sun, Lu Xu, Yuee Teng, Xiaoyi Mi, Lei Zhao, Qiaochu Wei
Publikováno v:
Oncology Research and Treatment. 43:620-627
Purpose: At the first time of metastatic breast cancer recurrence, conversion of the receptors status may occur between primary lesions and metastatic lesions, including the estrogen receptor (ER), progesterone receptor (PR), and human epidermal grow
Autor:
Mitsuhiro Kamiyoshihara, Shigefumi Tanaka, Kyoichi Kaira, Takayuki Asao, Kazuyoshi Imaizumi, Kimihiro Shimizu, Ken Shirabe, Atsushi Fujita, Hideki Endoh, Masayuki Sugano, Osamu Kawashima, Yoshihito Kogure, Tetsunari Oyama, Hisao Imai
Publikováno v:
Anticancer Research. 40:261-269
Background Pulmonary pleomorphic carcinoma (PPC) is a rare aggressive neoplasm, with dismal prognosis. Whether tumor immunity is associated with the progressive biological behavior of PPC remains unclear. The purpose of this study was to examine the