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pro vyhledávání: ''
Autor:
Emilia Durante, Vittorina Zagonel, Antonella Facchinetti, Michele Aieta, Alberto Diminutto, Carlo Gatti, Maurizio Nicodemo, Anna Paola Fraccon, Cristina Pegoraro, Claudia Mucciarini, Alessandra Bearz, Marco Maruzzo, Francesco Massari, Vincenza Conteduca, Rita Zamarchi, Umberto Basso, Ugo De Giorgi, Carmen Barile, Elisabetta Rossi, Matteo Santoni, Pasquale Fiduccia, Alessandra Perin, Teodoro Sava
Publikováno v:
Oncologist
Background Circulating tumor cells (CTCs) correlate with adverse prognosis in patients with breast, colorectal, lung, and prostate cancer. Little data are available for renal cell carcinoma (RCC). Materials and Methods We designed a multicenter prosp
Autor:
Navita Somaiah, Gift Nayamundanda, Carol Box, Selvakumar Anbalagan, Gargi Kothari, Anna M. Kirby, Annette Musallam, Victoria Sinnett, Sheng Yu, Fiona Castell, Charlotte Westbury, Elinor J. Sawyer, Steven D. Allen, John Yarnold, Virginia Wolstenholme, Lone Gothard, I. Locke, Claire Lucy, Kabir Mohammed, Samantha Nimalasena, Simon P. Robinson, Diana Tait, G. Ross, Susan Cleator
Publikováno v:
International Journal of Radiation Oncology*Biology*Physics. 108:1019-1029
Purpose Hydrogen peroxide (H2O2) plays a vital role in normal cellular processes but at supraphysiological concentrations causes oxidative stress and cytotoxicity, a property that is potentially exploitable for the treatment of cancer in combination
Publikováno v:
Anticancer Research. 40:5229-5235
Background/aim The prolactin receptor (PRLR) is implicated in the tumorigenesis of breast and prostate cancers where it drives cell proliferation, survival, and migration. LFA102 is a humanized monoclonal antibody against PRLR with promising preclini
Autor:
GEORGIOS N. TSAOUSIS, EIRINI PAPADOPOULOU, KONSTANTINOS AGIANNITOPOULOS, GEORGIA PEPE, NIKOLAOS TSOULOS, IOANNIS BOUKOVINAS, THEOFANIS FLOROS, RODONIKI IOSIFIDOU, OURANIA KATOPODI, ANNA KOUMARIANOU, CHRISTOS MARKOPOULOS, KONSTANTINOS PAPAZISIS, VASILEIOS VENIZELOS, ACHILLEAS KAPSIMALIS, GRIGORIOS XEPAPADAKIS, AMANDA PSYRRI, EUGENIU BANU, DAN TUDOR ENIU, ALEXANDRU BLIDARU, DANA LUCIA STANCULEANU, ANDREI UNGUREANU, VAHIT OZMEN, SUALP TANSAN, MEHMET TEKINEL, SUAYIB YALCIN, GEORGE NASIOULAS
Publikováno v:
Cancer Genomics Proteomics
Background/Aim: The use of multi-gene panels for germline testing in breast cancer enables the estimation of cancer risk and guides risk-reducing management options. The aim of this study was to present data that demonstrate the different levels of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17928cee2350acf8044f319ac3d2bec4
https://europepmc.org/articles/PMC8717958/
https://europepmc.org/articles/PMC8717958/
Autor:
Teppei Sugano, Kenji Tamura, Mari Masuda, Makiko Ono, Masayuki Yoshida, Akihiko Gemma, Tesshi Yamada, Hitoshi Tsuda, Takayuki Kinoshita, Kazufumi Honda
Publikováno v:
British Journal of Cancer
Background Most patients with hormone receptor (HR)-positive, human epidermal growth factor receptor type 2 (HER2)-negative breast cancer can be cured by surgery and endocrine therapy, but a significant proportion suffer recurrences. Actinin-4 is ass
Autor:
Vincent Antao, Mohammad Jahanzeb, Denise A. Yardley, Joyce O'Shaughnessy, Peter A. Kaufman, Ginny Mason, Adam Brufsky, Sara A. Hurvitz, Laura Chu, Melody A. Cobleigh, Hope S. Rugo, Sandra M. Swain, Debu Tripathy, Haocheng Li
Publikováno v:
Clinical Cancer Research. 26:1105-1113
Purpose: We report treatments and outcomes in a contemporary patient population with HER2-positive metastatic breast cancer (MBC) by hormone receptor (HR) status from the Systemic Therapies for HER2-positive Metastatic Breast Cancer Study (SystHERs).
Autor:
E. Shelley Hwang, Terry Hyslop, Rachel A. Greenup, Jennifer K. Plichta, Rebecca Vernon, Oluwadamilola M. Fayanju, Samantha M. Thomas, Laura H. Rosenberger
Publikováno v:
Breast Cancer Res Treat
BACKGROUND: Given presumed differences in disease severity between young (≤ 45 years) and elderly (≥ 75 years) women with breast cancer, we sought to compare tumor histopathology, stage at presentation, patterns of care, and survival at the extre
Autor:
Jeong Eon Lee, Byung Joo Chae, Jonghan Yu, Jai Min Ryu, Seok Jin Nam, Seok Won Kim, Se Kyung Lee
Publikováno v:
Japanese Journal of Clinical Oncology. 50:104-113
Objective Demands for genetic counseling with BRCA1/2 examination have markedly increased. Accordingly, the incidence of uninformative results on BRCA1/2 mutation status has also increased. Because most patients examined for BRCA1/2 mutation have a h
Autor:
Tuya Pal, Christina E. Bailey, Wei Zheng, Ingrid A. Mayer, Xiao-Ou Shu, Ingrid M. Meszoely, Ben Ho Park, Fei Wang, Sonya Reid
Publikováno v:
Clin Cancer Res
Purpose: Prognostic value of Oncotype DX Breast Recurrence Score (RS) in male patients with breast cancer is understudied. We evaluated associations of RS with overall mortality in male patients with breast cancer and compared it with female counterp
Autor:
Prabhat Singh Malik, S V Suryanarayana Deo, Ajay Gogia, Sandeep Mathur, Rakesh K. Phulia, Dayanand Sharma, Sanjay Thulkar
Publikováno v:
Journal of Global Oncology
Journal of Global Oncology, Vol 5, Pp 1-8 (2019)
Journal of Global Oncology, Vol 5, Pp 1-8 (2019)
PURPOSE Biomarker—estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER2/ neu) —discordance plays an essential role in the management and prognosis of patients with metastatic breast cancer. Rates o