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Autor:
Chenlu Zhang, Xiaojing Xu, Shengchao Wu, Wei Guo, Fei Huang, Yiyi Yu, Tianshu Liu, Mengling Liu, Li Liang, Minna Shen
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-10 (2020)
BMC Cancer
BMC Cancer
Background The aim of this study was to explore the utility of circulating free DNA (cfDNA) in the evaluation of clinical tumor burden and survival in Chinese patients with metastatic colorectal cancer (mCRC) and to preliminarily summarize some metas
Autor:
Krishnamurthy Ganesh, Suresh K. Rayala, Himavani Pacharla, Roshni Saravanan, Lawrence D'Cruze, Veena Kumari Vuttaradhi, Karthika P Padmavathy, Ganesh Venkatraman, Ravishankar Pitani, D Prathiba, Akkanapally Venu
Publikováno v:
Journal of Molecular Neuroscience. 71:724-733
Malignant astrocytomas presenting in humans of any age group are a challenge to diagnose and treat. Hence, there is a quest for new markers to ascertain their grades and predict disease outcomes. Proline, glutamic acid, and leucine-rich protein 1 (PE
Autor:
Jesper Lagergren, Eivind Ness-Jensen, Hilde Langseth, Shao-Hua Xie, Randi Elin Gislefoss, Fredrik Mattsson
Publikováno v:
International Journal of Cancer
Sex hormonal differences may contribute to the strong male predominance in esophageal adenocarcinoma (EAC), but whether sex hormone levels influence survival in EAC is unstudied. Our study aimed to assess associations between prediagnostic sex hormon
Publikováno v:
Anticancer Research. 39:6871-6875
BACKGROUND/AIM The aim of the present study was to determine whether serum lactate dehydrogenase (LDH) levels before treatment could predict the disease-specific and event-free survival in adult patients with STS. PATIENTS AND METHODS A total of 142
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports
Scientific Reports
GREB1L is a protein-coding gene that is an important paralog of GREB1. However, its effects in lung adenocarcinoma (LUAD) have not been determined. Thus, we evaluated the prognostic value of GREB1L in LUAD using bioinformatics approaches. In particul
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 5382, p 5382 (2021)
International journal of molecular sciences, vol 22, iss 10
International Journal of Molecular Sciences
Volume 22
Issue 10
International journal of molecular sciences, vol 22, iss 10
International Journal of Molecular Sciences
Volume 22
Issue 10
(1) Background: methionine cycle is not only essential for cancer cell proliferation but is also critical for metabolic reprogramming, a cancer hallmark. Hepatic and extrahepatic tissues methionine adenosyltransferases (MATs) are products of two gene
Publikováno v:
Thoracic Cancer, Vol 10, Iss 6, Pp 1395-1401 (2019)
Thoracic Cancer
Thoracic Cancer
e15559 Background: A small proportion of patients with advanced esophageal squamous cell carcinoma (ESCC) could benefit from immune checkpoint inhibitors, and reliable peripheral blood biomarkers for outcomes of anti-PD-1 immunotherapy were not ident
Autor:
Peiyuan Wang, Qin Wang, Weiwei Yang, Shiyao Sui, Kun Qiao, Jinfeng Zhang, Hao Wu, Jian Zhang, Shouping Xu, Hongbiao Xu, Da Pang
Publikováno v:
Molecular Cancer, Vol 18, Iss 1, Pp 1-18 (2019)
Molecular Cancer
Molecular Cancer
Background The biology function of antisense intronic long noncoding RNA (Ai-lncRNA) is still unknown. Meanwhile, cancer patients with paclitaxel resistance have limited therapeutic options in the clinic. However, the potential involvement of Ai-lncR
Autor:
Ninette Amariglio, Itay Zilbershats, Noam Benyamini, Gabriela Rozic, Luba Trakhtenbrot, Merav Leiba, Olga Shevetz, Adrian Duek, Ronit Leiba, Arnon Nagler, Chezi Ganzel
Publikováno v:
Genes, Chromosomes and Cancer. 58:516-520
The current study evaluated the prognostic significance of the monoallelic deletion of the whole locus of the immunoglobulin heavy-chain (w_del(IGH)) gene compared to translocations t(4;14) and t(14;16) among newly diagnosed multiple myeloma (MM) pat
Preselection of Lung Cancer Cases Using FGFR1 mRNA and Gene Copy Number for Treatment With Ponatinib
Autor:
D. Ross Camidge, Derek E. Smith, Dara L. Aisner, Adrie van Bokhoven, Theresa A. Boyle, Dexiang Gao, Hui Yu, Emily R. York, Scott Leedy, Lynn E. Heasley, Terry L. Ng, Fred R. Hirsch
Publikováno v:
Clinical Lung Cancer. 20:e39-e51
Introduction Preclinically, high epidermal growth factor receptor 1 (FGFR1) messenger RNA (FGFR1-MRNA) and FGFR1 amplification (FGFR1-AMP) predicted sensitivity to fibroblast growth factor receptor inhibitors in non–small-cell lung cancer and small