Zobrazeno 1 - 10
of 11 621
pro vyhledávání: ''
Autor:
Virginia Paton, Gracie Lieberman, Melody A. Cobleigh, Debasish Tripathy, Nicholas J. Robert, Charles L. Vogel, Louis Fehrenbacher, Janet M. Wolter, Steven Shak, Susy Scholl, Dennis J. Slamon
Publikováno v:
Journal of Clinical Oncology. 41:1501-1510
PURPOSE Overexpression of the HER2 protein occurs in 25% to 30% of human breast cancers and leads to a particularly aggressive form of the disease. Efficacy and safety of recombinant humanized anti-HER2 monoclonal antibody as a single agent was evalu
Autor:
Atsushi Itou, Naoya Nakamura, Joaquim Carreras, Sawako Shiraiwa, Kiyoshi Ando, Sakura Tomita, Masashi Miyaoka, Haruka Ikoma, Yara Yukie Kikuti
Publikováno v:
Pathology International. 72:35-42
Diffuse large B-cell lymphoma with MYC rearrangement is defined as double/triple-hit lymphoma (DHL/THL) or single-hit lymphoma (SHL) by the inclusion of the BCL2 and BCL6 rearrangements status. DHL/THL is called as "high-grade B-cell lymphoma with MY
Autor:
Lucile Bussot, Simon Chevalier, Caroline Algrin, Anouk Emadali, Laurence David-Boudet, Christine Lefebvre, Cyril Fournier, Laurent Martin, Claire Vettier, O. Casasnovas, Remy Gressin, Caroline Chapusot, Mary Callanan, Edwige Col, Thierry Bonnefoix, Marie-Christine Jacob, Anne McLeer, Antonin Bouroumeau, Tatiana Raskovalova, Hervé Sartelet
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 6, Pp 604-615 (2021)
The Journal of Pathology: Clinical Research
The Journal of Pathology: Clinical Research
Diffuse large B‐cell lymphoma (DLBCL) is a clinically heterogeneous entity, in which the first‐line treatment currently consists of an immuno‐chemotherapy regimen (R‐CHOP). However, around 30% of patients will not respond or will relapse. Ove
Autor:
Jan Borén, Levent M. Akyürek, Per Fogelstrand, Matias Ekstrand, Joakim Karlsson, Max Levin, Malin Levin, Keith E. Mostov, Lars Ny, Martin O. Bergo, Jonas Nilsson, Sara Bjursten, Zhiyuan Zhao, Kristell Le Gal, Andrew J. Ewald, Ankur Pandita
Publikováno v:
The American journal of pathology, vol 191, iss 11
Am J Pathol
Am J Pathol
Angiogenesis supplies oxygen and nutrients to growing tumors. Inhibiting angiogenesis may stop tumor growth, but vascular endothelial growth factor inhibitors have limited effect in most tumors. This limited effect may be explained by an additional,
Autor:
Tsuyoshi Kurai, Mishie Tanino, Shinya Tanaka, Masumi Tsuda, Lei Wang, Yusuke Ishida, Yuji Ichihashi, Masahiro Asaka, Misa Noguchi, Koki Ise, Satoshi Hirano
Publikováno v:
Cancer Science
In 2020, the worldwide incidence and mortality of colorectal cancer (CRC) were third and second, respectively. As the 5‐y survival rate is low when CRC is diagnosed at an advanced stage, a reliable method to predict CRC susceptibility is important
Autor:
Yoshiaki Shiokawa, Takaki Omura, Saki Shimizu, Koichi Ichimura, Motoo Nagane, Akihide Kondo, Kuniaki Saito, Yoshitaka Narita, Yuko Matushita, Keiichi Kobayashi, Nobuyoshi Sasaki, Yoshiko Nakano, Yuki Yamagishi
Publikováno v:
Cancer Science
The current standard of diagnosing central nervous system (CNS) lymphoma is stereotactic biopsy, however the procedure has a risk of surgical complication. Liquid biopsy of the CSF is a less invasive, non‐surgical method that can be used for diagno
Autor:
Anna Christina Strobl, Tim H. H. Coorens, Adrienne M. Flanagan, Solange De Noon, Sam Behjati, Iben Lyskjaer, Jannat Ijaz, Fernanda Amary, Hongtao Ye
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 7, Iss 5, Pp 425-431 (2021)
Lyskjær, I 2021, ' MYC amplifications are common events in childhood osteosarcoma ', The journal of pathology. Clinical research . https://doi.org/10.1002/cjp2.219
De Noon, S, Ijaz, J, Coorens, T H H, Amary, F, Ye, H, Strobl, A, Lyskjær, I, Flanagan, A M & Behjati, S 2021, ' MYC amplifications are common events in childhood osteosarcoma ', Journal of Pathology: Clinical Research . https://doi.org/10.1002/cjp2.219
The Journal of Pathology: Clinical Research
Lyskjær, I 2021, ' MYC amplifications are common events in childhood osteosarcoma ', The journal of pathology. Clinical research . https://doi.org/10.1002/cjp2.219
De Noon, S, Ijaz, J, Coorens, T H H, Amary, F, Ye, H, Strobl, A, Lyskjær, I, Flanagan, A M & Behjati, S 2021, ' MYC amplifications are common events in childhood osteosarcoma ', Journal of Pathology: Clinical Research . https://doi.org/10.1002/cjp2.219
The Journal of Pathology: Clinical Research
Osteosarcoma, the most common primary malignant tumour of bone, affects both children and adults. No fundamental biological differences between paediatric and adult osteosarcoma are known. Here, we apply multi‐region whole‐genome sequencing to an
Autor:
Kyoichi Kaira, Ou Yamaguchi, Hiroyuki Nitanda, Hirozo Sakaguchi, Akitoshi Yanagihara, Hiroshi Kagamu, Tomonori Kawasaki, Tetsuya Umesaki, Kunihiko Kobayashi, Atsuto Mouri, Hisao Imai, Kosuke Hashimoto, Ryo Taguchi, Ichiei Kuji, Masanori Yasuda
Publikováno v:
Cancer Medicine, Vol 10, Iss 18, Pp 6317-6326 (2021)
Cancer Medicine
Cancer Medicine
Background 2‐deoxy‐2‐[fluorine‐18] fluoro‐d‐glucose (18F‐FDG) positron emission tomography (18F‐FDG‐PET) is a convenient modality to assess the metabolic activity within tumor cells. However, there is no consensus regarding the rela
Publikováno v:
Cancer Cytopathology. 129:973-983
Background Although largely readily recognizable in tissue sections, acinic cell carcinoma (ACC) remains diagnostically problematic in fine-needle aspiration (FNA) cytopathology. The authors undertook an analysis of a large series of ACC aspirates, i
Autor:
Mai Iwaya, Tomoyuki Nakajima, Takayuki Watanabe, Yusuke Miyagawa, Yasuhiro Kinugawa, Takeshi Uehara, Takashi Muraki, Yasuhiro Kuraishi, Takeji Umemura
Publikováno v:
Diagnostic Pathology, Vol 16, Iss 1, Pp 1-8 (2021)
Diagnostic Pathology
Diagnostic Pathology
Background Pancreaticobiliary maljunction (PBM) is a condition characterized by chronic inflammation due to refluxed pancreatic juice into the biliary tract that is associated with an elevated risk of biliary tract cancer. DNA double-strand breaks (D