Zobrazeno 101 - 110
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Autor:
Ahmet Dogan, Do Hwan Kim, Chi Young Ok, Francisco Vega, Ali Sakhdari, Michael L. Wang, Rashmi Kanagal-Shamanna, Diana Martinez-Baquero, Ken H. Young, Huan Mo, Timothy J. McDonnell, Preetesh Jain, Dennis P. O'Malley, Shaoying Li, L. Jeffrey Medeiros, Roberto N. Miranda
Publikováno v:
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. 34(12)
Enhancer of zeste homolog 2 (EZH2) is a catalytic component of the polycomb repressive complex 2 (PRC2) which reduces gene expression via trimethylation of a lysine residue of histone 3 (H3K27me3). Expression of EZH2 has not been assessed systematica
Autor:
Zafer Kucukodaci, Atila Gungor, Evren Erkul, Ersin Tural, Ismail Yilmaz, Gizem Issin, Sukru Yildirim, Dilaver Demirel
Publikováno v:
Türk Patoloji Dergisi, Vol 37, Iss 2, Pp 106-114 (2021)
Objective Although squamous cell carcinomas (SCCs) originating from different anatomic localizations display a similar histological appearance under light microscopy, they may differ in terms of epigenetic and genetic features. The aim of this study
Publikováno v:
Breast disease. 40(2)
BACKGROUND: Little information is available on male breast cancer (MBC) incidence from sub-Saharan Africa. OBJECTIVE: This is a retrospective study on MBC in rural North Uganda, based on the pathology records of a private, non-profit, missionary hosp
Autor:
Claire Danel, Aurélie Sannier, Jean-Michel Rodier, Anne Couvelard, S. Brosseau, Hussein Nassereddine, Aurélie Cazes, Antoine Khalil, Simon Msika, Nathalie Théou-Anton
Publikováno v:
Pathology & Oncology Research. 26:2795-2800
To retrospectively characterize the molecular features of Non-Small Cell Lung Carcinomas (NSCLC) with peritoneal carcinomatosis (PC), clinicopathological data of 12 patients diagnosed with NSCLC and PC between 2007 and 2016 were collected. Immunohist
TP53 mutations are common in mantle cell lymphoma, including the indolent leukemic non-nodal variant
Autor:
Rajyalakshmi Luthra, Ali Sakhdari, Sanam Loghavi, Zhuang Zuo, Keyur P. Patel, Rashmi Kanagal-Shamanna, Shimin Hu, L. Jeffrey Medeiros, Chi Young Ok, Mark J. Routbort, C. Cameron Yin, Joseph D. Khoury
Publikováno v:
Web of Science
Introduction Mantle cell lymphoma (MCL) is an aggressive B-cell neoplasm, but clinically indolent subtypes are also recognized. Data on the utility of mutation profiling in the context of routine workup and its role in risk-stratification of MCL pati
Autor:
Kyoko Hosaka, Takashi Hagimoto, Masao Omata, Kenji Amemiya, Hitoshi Mochizuki, Yosuke Hirotsu, Hironori Daimon, Toshio Oyama, Hitoshi Yokoyama
Publikováno v:
Cancer Science
Cytology is widely conducted for diagnosis of urothelial bladder cancer; however, its sensitivity is still low. Recent studies show that liquid biopsies can reflect tumor genomic profiles. We aim to investigate whether plasma or urine is more suitabl
Autor:
Atsushi Ochiai, Genichiro Ishii, Erika Suzuki, Tomoyuki Naito, Satoshi Okubo, Shota Yamazaki, Masahiro Tsuboi, Koichi Goto, Hibiki Udagawa, Hiroko Hashimoto
Publikováno v:
Pathology International. 69:472-480
Humoral factors from cancer-associated fibroblasts (CAFs) reportedly affect epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI) resistance in cancer cells with EGFR mutations. The aim of this study was to identify the robust humoral
Autor:
Jeong Youp Park, Si Young Song, Eun Kyung Kim, Hoguen Kim, Moon Jae Chung, Jin-Young Lee, Seungmin Bang, Seung Woo Park, Hee Seung Lee, Jae Seung Lee
Publikováno v:
Cancer Medicine, Vol 8, Iss 7, Pp 3339-3348 (2019)
Cancer Medicine
Cancer Medicine
Recent studies have identified the mutational landscape of pancreatic cancer and suggested tumor‐specific subtypes. However, the major hurdle against personalized treatment is the difficulty to obtain sufficient cancer tissues from most inoperable
Autor:
Lijie Song, Weili Tao, Xuxu Yu, Shunli Yu, Feng Wang, Minjie Yang, Shuang Tao, Yujin Lian, Yihui Ma, Xuejia Zhai, Qingxia Fan
Publikováno v:
Cancer Medicine, Vol 8, Iss 8, Pp 3729-3737 (2019)
Cancer Medicine
Cancer Medicine
Background Neuroendocrine tumors (NETs) are rare, which has resulted in a lack of published data on their epidemiology and clinical features. We therefore aimed to investigate the epidemiology, clinical features, treatments, and prognosis of patients
Autor:
Carlos E. de Andrea, Maria D. Lozano, Juan Berto, Alfonso Calvo, Alfonso Gurpide, José I. Echeveste, Jose Carlos Subtil, Marta Abengozar-Muela
Publikováno v:
Cancer Cytopathology. 127:470-480
Background Programmed death-ligand 1 (PD-L1) expression, as assessed by immunohistochemistry (IHC), is used to select patients with non-small cell lung cancer (NSCLC) for anti-programmed cell death protein 1 (PD-1)/PD-L1 therapy. The current study ev