Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Michael T. Williams"'
Publikováno v:
Toxicology and Applied Pharmacology. 354:176-190
High throughput screens for developmental neurotoxicity (DN) will facilitate evaluation of chemicals and can be used to prioritize those designated for follow-up. DN is evaluated under different guidelines. Those for drugs generally include peri- and
Publikováno v:
Toxicological Sciences. 165:361-371
Permethrin is a type I (noncyano) pyrethroid that induces tremors at high concentrations and increases acoustic startle responses (ASRs) in adult rodents, however its effects in young rats have been investigated to a limited extent. ASR and tremor we
Autor:
Michael T. Williams, Paula A. Soto, Robyn M. Amos-Kroohs, Rocío Martinez Vivot, Vanina Usach, Charles V. Vorhees, Gonzalo Piñero, Patricia Setton-Avruj
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Iron (Fe) deficiency (FeD) and manganese (Mn) overexposure (MnOE) may result in several neurological alterations in the nervous system. Iron deficiency produces unique neurological deficits due to its elemental role in central nervous system (CNS) de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac065dcb7d5daadbf6d07d0d20004091
https://pubmed.ncbi.nlm.nih.gov/30652531/
https://pubmed.ncbi.nlm.nih.gov/30652531/
Autor:
Michael T. Williams, Curtis E. Grace, Matthew R. Skelton, Robyn M. Amos-Kroohs, Devon L. Graham, Charles V. Vorhees, Tori L. Schaefer, Amanda A. Braun
Publikováno v:
NeuroToxicology. 54:22-33
The level of lead (Pb) exposure in children has decreased dramatically since restrictions on its use were implemented. However, even with restrictions, children are exposed to Pb and still present with cognitive and behavioral deficits. One prominent
Autor:
Arnold Gutierrez, Jillian R. Hufgard, Jenna L.N. Sprowles, Rebecca A. Bailey, Michael T. Williams, Charles V. Vorhees, Sarah A. Jablonski
Publikováno v:
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. 54
Selective serotonin reuptake inhibitors (SSRIs) block the serotonin (5-HT) reuptake transporter (SERT) and increase synaptic 5-HT. 5-HT is also important in brain development; hence when SSRIs are taken during pregnancy there exists the potential for
Effects of neonatal methamphetamine treatment on adult stress-induced corticosterone release in rats
Autor:
Curtis E. Grace, Charles V. Vorhees, Michael T. Williams, Nicole R. Herring, Tori L. Schaefer
Publikováno v:
Neurotoxicology and Teratology. 34:136-142
In rats, neonatal (+)-methamphetamine (MA) exposure and maternal separation stress increase corticosterone during treatment and result in learning and memory impairments later in life. Early-life stress also changes later responses to acute stress. W
Publikováno v:
Behavioural Pharmacology. 18:549-562
Neonatal rats exposed to (+)-methamphetamine (MA) display spatial learning and reference memory deficits in the Morris water maze. In separate experiments the emergence and permanence of these effects were determined. Twenty litters were used in each
Publikováno v:
Psychopharmacology. 189:307-318
Previous studies in rats showed that postnatal day (P)11–20 exposure to ±3,4-methylenedioxymethamphetamine (MDMA, ecstasy) causes learning and memory deficits in adulthood. The emergence and permanence of these learning deficits are currently unkn
Autor:
Jessica A. Able, Renu Sah, Gary A. Gudelsky, Charles V. Vorhees, Tori L. Schaefer, Michael T. Williams, Lisa A. Ehrman
Publikováno v:
Brain Research. 1039:97-107
We have previously shown that +/-3,4-methylenedioxymethamphetamine (MDMA) treatment from P11 to P20 in rats produces deficits in cognitive ability when these animals are tested in adulthood. The purpose of this experiment was to explore the neuroendo
Autor:
Sandra L. Wood, Stephanie L. Rock, Michael T. Williams, Charles V. Vorhees, Tracy M. Reed, Carrie A. Brown, LaRonda L Morford, Masao Fukumura, Matthew R. Skelton, Anne E McCrea
Publikováno v:
Neurotoxicology and Teratology. 27:117-134
We have previously shown that P11-20 treatment with d-methamphetamine (MA) induces impaired spatial navigation in the Morris water maze (MWM), whereas P1-10 treatment does not. Little is known about the long-term behavioral consequences of MA during