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Autor:
Jennifer L. Gommerman, Dania Haddad, Ahmad Zaheen, Olga L. Rojas, Bryant Boulianne, Alberto Martin, Razq Hakem, Thanh Nguyen, Anat Kapelnikov, Conglei Li
Publikováno v:
The Journal of Immunology. 191:5840-5847
Germinal centers (GCs) are clusters of activated B cells that form in secondary lymphoid organs during a T-dependent immune response. B cells enter GCs and become rapidly proliferating centroblasts that express the enzyme activation-induced deaminase