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of 18
pro vyhledávání: '"Traylor, Matthew"'
Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants
Autor:
Persyn, Elodie, Hanscombe, Ken B, Howson, Joanna MM, Lewis, Cathryn M, Traylor, Matthew, Markus, Hugh S
Cerebral small vessel disease is a major cause of stroke and dementia, but its genetic basis is incompletely understood. We perform a genetic study of three MRI markers of the disease in UK Biobank imaging data and other sources: white matter hyperin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______109::aae77afbb977cb6c81fee8f421e422a6
https://www.repository.cam.ac.uk/handle/1810/303930
https://www.repository.cam.ac.uk/handle/1810/303930
Genome-wide association study of MRI markers of cerebral small vessel disease in 42,310 participants
Autor:
Persyn, Elodie, Hanscombe, Ken B, Howson, Joanna MM, Lewis, Cathryn M, Traylor, Matthew, Markus, Hugh S
Cerebral small vessel disease is a major cause of stroke and dementia, but its genetic basis is incompletely understood. We perform a genetic study of three MRI markers of the disease in UK Biobank imaging data and other sources: white matter hyperin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a355fa782487761ea81616d3abb3a692
Autor:
Coleman, Jonathan RI, Peyrot, Wouter J, Purves, Kirstin L, Davis, Katrina AS, Rayner, Christopher, Choi, Shing Wan, Hubel, Christopher, Gaspar, Helena A, Kan, Carol, Van der Auwera, Sandra, Adams, Mark James, Lyall, Donald M, Choi, Karmel W, Dunn, Erin C, Vassos, Evangelos, Danese, Andrea, Maughan, Barbara, Grabe, Hans J, Lewis, Cathryn M, O'Reilly, Paul F, McIntosh, Andrew M, Smith, Daniel J, Wray, Naomi R, Hotopf, Matthew, Eley, Thalia C, Breen, Gerome, Ripke, Stephan, Mattheisen, Manuel, Trzaskowski, Maciej, Byrne, Enda M, Abdellaoui, Abdel, Adams, Mark J, Agerbo, Esben, Air, Tracy M, Andlauer, Till FM, Bacanu, Silviu-Alin, Baekvad-Hansen, Marie, Beekman, Aartjan TF, Bigdeli, Tim B, Binder, Elisabeth B, Bryois, Julien, Buttenschon, Henriette N, Bybjerg-Grauholm, Jonas, Cai, Na, Castelao, Enrique, Christensen, Jane Hvarregaard, Clarke, Toni-Kim, Colodro-Conde, Lucia, Couvy-Duchesne, Baptiste, Craddock, Nick, Crawford, Gregory E, Davies, Gail, Deary, Ian J, Degenhardt, Franziska, Derks, Eske M, Direk, Nese, Dolan, Conor V, Escott-Price, Valentina, Kiadeh, Farnush Farhadi Hassan, Finucane, Hilary K, Foo, Jerome C, Forstner, Andreas J, Frank, Josef, Gill, Michael, Goes, Fernando S, Gordon, Scott D, Grove, Jakob, Hall, Lynsey S, Hansen, Christine Soholm, Hansen, Thomas F, Herms, Stefan, Hickie, Ian B, Hoffmann, Per, Homuth, Georg, Horn, Carsten, Hottenga, Jouke-Jan, Hougaard, David M, Howard, David M, Ising, Marcus, Jansen, Rick, Jones, Ian, Jones, Lisa A, Jorgenson, Eric, Knowles, James A, Kohane, Isaac S, Kraft, Julia, Kretzschmar, Warren W, Kutalik, Zoltan, Li, Yihan, Lind, Penelope A, MacIntyre, Donald J, MacKinnon, Dean F, Maier, Robert M, Maier, Wolfgang, Marchini, Jonathan, Mbarek, Hamdi, McGrath, Patrick, McGuffin, Peter, Medland, Sarah E, Mehta, Divya, Middeldorp, Christel M, Mihailov, Evelin, Milaneschi, Yuri, Milani, Lili, Mondimore, Francis M, Montgomery, Grant W, Mostafavi, Sara, Mullins, Niamh, Nauck, Matthias, Ng, Bernard, Nivard, Michel G, Nyholt, Dale R, Oskarsson, Hogni, Owen, Michael J, Painter, Jodie N, Pedersen, Carsten Bocker, Pedersen, Marianne Giortz, Peterson, Roseann E, Pettersson, Erik, Pistis, Giorgio, Posthuma, Danielle, Quiroz, Jorge A, Qvist, Per, Rice, John P, Riley, Brien P, Rivera, Margarita, Mirza, Saira Saeed, Schoevers, Robert, Schulte, Eva C, Shen, Ling, Shi, Jianxin, Shyn, Stanley I, Sigurdsson, Engilbert, Sinnamon, Grant CB, Smit, Johannes H, Stefansson, Hreinn, Steinberg, Stacy, Streit, Fabian, Strohmaier, Jana, Tansey, Katherine E, Teismann, Henning, Teumer, Alexander, Thompson, Wesley, Thomson, Pippa A, Thorgeirsson, Thorgeir E, Traylor, Matthew, Treutlein, Jens, Trubetskoy, Vassily, Uitterlinden, Andres G, Umbricht, Daniel, van Hemert, Albert M, Viktorin, Alexander, Visscher, Peter M, Wang, Yunpeng, Webb, Bradley T, Weinsheimer, Shantel Marie, Wellmann, Jurgen, Willemsen, Gonneke, Witt, Stephanie H, Wu, Yang, Xi, Hualin S, Yang, Jian, Zhang, Futao, Arolt, Volker, Baune, Bernhard T, Berger, Klaus, Boomsma, Dorret I, Cichon, Sven, Dannlowski, Udo, de Geus, EJC, DePaulo, J Raymond, Domenici, Enrico, Domschke, Katharina, Esko, Tonu, Hamilton, Steven P, Hayward, Caroline, Heath, Andrew C, Kendler, Kenneth S, Kloiber, Stefan, Lewis, Glyn, Li, Qingqin S, Lucae, Susanne, Madden, Pamela AF, Magnusson, Patrik K, Martin, Nicholas G, Metspalu, Andres, Mors, Ole, Mortensen, Preben Bo, Mueller-Myhsok, Bertram, Nordentoft, Merete, Noethen, Markus M, O'Donovan, Michael C, Paciga, Sara A, Pedersen, Nancy L, Penninx, Brenda WJH, Perlis, Roy H, Porteous, David J, Potash, James B, Preisig, Martin, Rietschel, Marcella, Schaefer, Catherine, Schulze, Thomas G, Smoller, Jordan W, Stefansson, Kari, Tiemeier, Henning, Uher, Rudolf, Volzke, Henry, Weissman, Myrna M, Werge, Thomas, Levinson, Douglas F, Borglum, Anders D, Sullivan, Patrick F, Consortium, Psychiat Genomics
Publikováno v:
Coleman, J R I, Peyrot, W J, Purves, K, Davis, K A S, Rayner, C, Choi, S W, Huebel, C, Gaspar, H A, Kan, C, der Auwera, S V, Adams, M J, Lyall, D, Choi, K W, Dunn, E C, Vassos, E, Danese, A, Maughan, B, Grabe, H J, Lewis, C M, O'Reilly, P F, McIntosh, A M, Smith, D J, Wray, N R, Hotopf, M, Eley, T & Breen, G & Howard, D 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, no. 7, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Molecular Psychiatry, 25, 1430-1446. NATURE PUBLISHING GROUP
Molecular psychiatry
Coleman, J R I & Adams, M J & McIntosh, A 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry . https://doi.org/10.1038/s41380-019-0546-6
MOLECULAR PSYCHIATRY
Molecular Psychiatry, 25(7), 1430-1446. Nature Publishing Group
Coleman, J R I, Peyrot, W J, Purves, K L, Davis, K A S, Rayner, C, Choi, S W, Hübel, C, Gaspar, H A, Kan, C, Van der Auwera, S, Adams, M J, Lyall, D M, Choi, K W, Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T F M, Bacanu, S A, Bækvad-Hansen, M, Beekman, A T F, Bigdeli, T B, Binder, E B, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T K, Coleman, J R I, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Direk, N, Dolan, C V, Dunn, E C, Eley, T C, Escott-Price, V, Kiadeh, F F H, Finucane, H K, Foo, J C, Forstner, A J, Frank, J, Gaspar, H A, Gill, M, Goes, F S, Gordon, S D, Grove, J, Hall, L S, Hansen, C S, Hansen, T F, Herms, S, Hickie, I B, Hoffmann, P, Homuth, G, Horn, C, Hottenga, J J, Hougaard, D M, Howard, D M, Ising, M, Jansen, R, Jones, I, Jones, L A, Jorgenson, E, Knowles, J A, Kohane, I S, Kraft, J, Kretzschmar, W W, Kutalik, Z, Li, Y, Lind, P A, MacIntyre, D J, MacKinnon, D F, Maier, R M, Maier, W, Marchini, J, Mbarek, H, McGrath, P, McGuffin, P, Medland, S E, Mehta, D, Middeldorp, C M, Mihailov, E, Milaneschi, Y, Milani, L, Mondimore, F M, Montgomery, G W, Mostafavi, S, Mullins, N, Nauck, M, Ng, B, Nivard, M G, Nyholt, D R, O’Reilly, P F, Oskarsson, H, Owen, M J, Painter, J N, Pedersen, C B, Pedersen, M G, Peterson, R E, Pettersson, E, Peyrot, W J, Pistis, G, Posthuma, D, Quiroz, J A, Qvist, P, Rice, J P, Riley, B P, Rivera, M, Mirza, S S, Schoevers, R, Schulte, E C, Shen, L, Shi, J, Shyn, S I, Sigurdsson, E, Sinnamon, G C B, Smit, J H, Smith, D J, Stefansson, H, Steinberg, S, Streit, F, Strohmaier, J, Tansey, K E, Teismann, H, Teumer, A, Thompson, W, Thomson, P A, Thorgeirsson, T E, Traylor, M, Treutlein, J, Trubetskoy, V, Uitterlinden, A G, Umbricht, D, Van der Auwera, S, van Hemert, A M, Viktorin, A, Visscher, P M, Wang, Y, Webb, B T, Weinsheimer, S M, Wellmann, J, Willemsen, G, Witt, S H, Wu, Y, Xi, H S, Yang, J, Zhang, F, Arolt, V, Baune, B T, Berger, K, Boomsma, D I, Cichon, S, Dannlowski, U, de Geus, E J C, DePaulo, J R, Domenici, E, Domschke, K, Esko, T, Grabe, H J, Hamilton, S P, Hayward, C, Heath, A C, Kendler, K S, Kloiber, S, Lewis, G, Li, Q S, Lucae, S, Madden, P A F, Magnusson, P K, Martin, N G, McIntosh, A M, Metspalu, A, Mors, O, Mortensen, P B, Müller-Myhsok, B, Nordentoft, M, Nöthen, M M, O’Donovan, M C, Paciga, S A, Pedersen, N L, Penninx, B W J H, Perlis, R H, Porteous, D J, Potash, J B, Preisig, M, Rietschel, M, Schaefer, C, Schulze, T G, Smoller, J W, Stefansson, K, Tiemeier, H, Uher, R, Völzke, H, Weissman, M M, Werge, T, Lewis, C M, Levinson, D F, Breen, G, Børglum, A D, Sullivan, P F, Dunn, E C, Vassos, E, Danese, A, Maughan, B, Grabe, H J, Lewis, C M, O’Reilly, P F, McIntosh, A M, Smith, D J, Wray, N R, Hotopf, M, Eley, T C, Breen, G & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, no. 7, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Coleman, J R I, Peyrot, W J, Purves, K L, Davis, K A S, Rayner, C, Choi, S W, Hubel, C, Gaspar, H A, Kan, C, Van der Auwera, S, Adams, M J, Lyall, D M, Choi, K W, Psychiat Genomics Consortium, Dunn, E C, Vassos, E, Danese, A, Maughan, B, Grabe, H J, Lewis, C M, O'Reilly, P F, McIntosh, A M, Smith, D J, Wray, N R, Hotopf, M, Eley, T C & Breen, G 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, no. 7, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Coleman, J R I, Peyrot, W J, Purves, K L, Davis, K A S, Rayner, C, Choi, S W, Hübel, C, Gaspar, H A, Kan, C, Van der Auwera, S, Adams, M J, Lyall, D M, Choi, K W, Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T F M, Bacanu, S A, Bækvad-Hansen, M, Beekman, A T F, Bigdeli, T B, Binder, E B, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T K, Coleman, J R I, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Hansen, C S, Hansen, T F, Pedersen, C B, Pedersen, M G, Nordentoft, M, Werge, T & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Molecular psychiatry, 25(7), 1430-1446. Nature Publishing Group
Coleman, J R I, Breen, G, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A, Dolan, C V, Hottenga, J J, Mbarek, H, Middeldorp, C M, Nivard, M G, Willemsen, G, Boomsma, D I, de Geus, E J C, Beekman, A T F, Jansen, R, Milaneschi, Y, Smit, J H, W J H Penninx, B & Posthuma, D 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, no. 7, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Molecular psychiatry, vol. 25, no. 7, pp. 1430-1446
Molecular Psychiatry, 25, 1430-1446. NATURE PUBLISHING GROUP
Molecular psychiatry
Coleman, J R I & Adams, M J & McIntosh, A 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry . https://doi.org/10.1038/s41380-019-0546-6
MOLECULAR PSYCHIATRY
Molecular Psychiatry, 25(7), 1430-1446. Nature Publishing Group
Coleman, J R I, Peyrot, W J, Purves, K L, Davis, K A S, Rayner, C, Choi, S W, Hübel, C, Gaspar, H A, Kan, C, Van der Auwera, S, Adams, M J, Lyall, D M, Choi, K W, Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T F M, Bacanu, S A, Bækvad-Hansen, M, Beekman, A T F, Bigdeli, T B, Binder, E B, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T K, Coleman, J R I, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Direk, N, Dolan, C V, Dunn, E C, Eley, T C, Escott-Price, V, Kiadeh, F F H, Finucane, H K, Foo, J C, Forstner, A J, Frank, J, Gaspar, H A, Gill, M, Goes, F S, Gordon, S D, Grove, J, Hall, L S, Hansen, C S, Hansen, T F, Herms, S, Hickie, I B, Hoffmann, P, Homuth, G, Horn, C, Hottenga, J J, Hougaard, D M, Howard, D M, Ising, M, Jansen, R, Jones, I, Jones, L A, Jorgenson, E, Knowles, J A, Kohane, I S, Kraft, J, Kretzschmar, W W, Kutalik, Z, Li, Y, Lind, P A, MacIntyre, D J, MacKinnon, D F, Maier, R M, Maier, W, Marchini, J, Mbarek, H, McGrath, P, McGuffin, P, Medland, S E, Mehta, D, Middeldorp, C M, Mihailov, E, Milaneschi, Y, Milani, L, Mondimore, F M, Montgomery, G W, Mostafavi, S, Mullins, N, Nauck, M, Ng, B, Nivard, M G, Nyholt, D R, O’Reilly, P F, Oskarsson, H, Owen, M J, Painter, J N, Pedersen, C B, Pedersen, M G, Peterson, R E, Pettersson, E, Peyrot, W J, Pistis, G, Posthuma, D, Quiroz, J A, Qvist, P, Rice, J P, Riley, B P, Rivera, M, Mirza, S S, Schoevers, R, Schulte, E C, Shen, L, Shi, J, Shyn, S I, Sigurdsson, E, Sinnamon, G C B, Smit, J H, Smith, D J, Stefansson, H, Steinberg, S, Streit, F, Strohmaier, J, Tansey, K E, Teismann, H, Teumer, A, Thompson, W, Thomson, P A, Thorgeirsson, T E, Traylor, M, Treutlein, J, Trubetskoy, V, Uitterlinden, A G, Umbricht, D, Van der Auwera, S, van Hemert, A M, Viktorin, A, Visscher, P M, Wang, Y, Webb, B T, Weinsheimer, S M, Wellmann, J, Willemsen, G, Witt, S H, Wu, Y, Xi, H S, Yang, J, Zhang, F, Arolt, V, Baune, B T, Berger, K, Boomsma, D I, Cichon, S, Dannlowski, U, de Geus, E J C, DePaulo, J R, Domenici, E, Domschke, K, Esko, T, Grabe, H J, Hamilton, S P, Hayward, C, Heath, A C, Kendler, K S, Kloiber, S, Lewis, G, Li, Q S, Lucae, S, Madden, P A F, Magnusson, P K, Martin, N G, McIntosh, A M, Metspalu, A, Mors, O, Mortensen, P B, Müller-Myhsok, B, Nordentoft, M, Nöthen, M M, O’Donovan, M C, Paciga, S A, Pedersen, N L, Penninx, B W J H, Perlis, R H, Porteous, D J, Potash, J B, Preisig, M, Rietschel, M, Schaefer, C, Schulze, T G, Smoller, J W, Stefansson, K, Tiemeier, H, Uher, R, Völzke, H, Weissman, M M, Werge, T, Lewis, C M, Levinson, D F, Breen, G, Børglum, A D, Sullivan, P F, Dunn, E C, Vassos, E, Danese, A, Maughan, B, Grabe, H J, Lewis, C M, O’Reilly, P F, McIntosh, A M, Smith, D J, Wray, N R, Hotopf, M, Eley, T C, Breen, G & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, no. 7, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Coleman, J R I, Peyrot, W J, Purves, K L, Davis, K A S, Rayner, C, Choi, S W, Hubel, C, Gaspar, H A, Kan, C, Van der Auwera, S, Adams, M J, Lyall, D M, Choi, K W, Psychiat Genomics Consortium, Dunn, E C, Vassos, E, Danese, A, Maughan, B, Grabe, H J, Lewis, C M, O'Reilly, P F, McIntosh, A M, Smith, D J, Wray, N R, Hotopf, M, Eley, T C & Breen, G 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, no. 7, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Coleman, J R I, Peyrot, W J, Purves, K L, Davis, K A S, Rayner, C, Choi, S W, Hübel, C, Gaspar, H A, Kan, C, Van der Auwera, S, Adams, M J, Lyall, D M, Choi, K W, Wray, N R, Ripke, S, Mattheisen, M, Trzaskowski, M, Byrne, E M, Abdellaoui, A, Adams, M J, Agerbo, E, Air, T M, Andlauer, T F M, Bacanu, S A, Bækvad-Hansen, M, Beekman, A T F, Bigdeli, T B, Binder, E B, Bryois, J, Buttenschøn, H N, Bybjerg-Grauholm, J, Cai, N, Castelao, E, Christensen, J H, Clarke, T K, Coleman, J R I, Colodro-Conde, L, Couvy-Duchesne, B, Craddock, N, Crawford, G E, Davies, G, Deary, I J, Degenhardt, F, Derks, E M, Hansen, C S, Hansen, T F, Pedersen, C B, Pedersen, M G, Nordentoft, M, Werge, T & on the behalf of Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Molecular psychiatry, 25(7), 1430-1446. Nature Publishing Group
Coleman, J R I, Breen, G, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium, Abdellaoui, A, Dolan, C V, Hottenga, J J, Mbarek, H, Middeldorp, C M, Nivard, M G, Willemsen, G, Boomsma, D I, de Geus, E J C, Beekman, A T F, Jansen, R, Milaneschi, Y, Smit, J H, W J H Penninx, B & Posthuma, D 2020, ' Genome-wide gene-environment analyses of major depressive disorder and reported lifetime traumatic experiences in UK Biobank ', Molecular Psychiatry, vol. 25, no. 7, pp. 1430-1446 . https://doi.org/10.1038/s41380-019-0546-6
Molecular psychiatry, vol. 25, no. 7, pp. 1430-1446
Depression is more frequent among individuals exposed to traumatic events. Both trauma exposure and depression are heritable. However, the relationship between these traits, including the role of genetic risk factors, is complex and poorly understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d4991e162bcb17808a3531fcc7d64b1
https://research.vu.nl/ws/files/121748816/Genomewide_geneenvironment_analyses_of_major_depressive_disorder_and_reported_lifetime_traumatic_experiences_in_UK_Biobank.pdf
https://research.vu.nl/ws/files/121748816/Genomewide_geneenvironment_analyses_of_major_depressive_disorder_and_reported_lifetime_traumatic_experiences_in_UK_Biobank.pdf
Autor:
Traylor, Matthew, Rutten-Jacobs, Loes CA, Thijs, Vincent, Holliday, Elizabeth G, Levi, Chris, Bevan, Steve, Malik, Rainer, Boncoraglio, Giorgio, Sudlow, Cathie, Rothwell, Peter M, Dichgans, Martin, Markus, Hugh S
Publikováno v:
Traylor, M S, Rutten-Jacobs, L C A, Thijs, V, Holliday, E G, Levi, C, Bevan, S, Malik, R, Boncoraglio, G B, Sudlow, C, Rothwell, P M, Dichgans, M & Markus, H S 2016, ' Genetic Associations With White Matter Hyperintensities Confer Risk of Lacunar Stroke ', Stroke .
Stroke; a Journal of Cerebral Circulation
Stroke; a Journal of Cerebral Circulation
Supplemental Digital Content is available in the text.
Background and Purpose— White matter hyperintensities (WMH) are increased in patients with lacunar stroke. Whether this is because of shared pathogenesis remains unknown. Using genetic dat
Background and Purpose— White matter hyperintensities (WMH) are increased in patients with lacunar stroke. Whether this is because of shared pathogenesis remains unknown. Using genetic dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::ebe46fec4bd39aa4523418a371564815
https://ora.ox.ac.uk/objects/uuid:b45ac896-0578-4eab-ad42-429536eced81
https://ora.ox.ac.uk/objects/uuid:b45ac896-0578-4eab-ad42-429536eced81
Autor:
Rutten-Jacobs, Loes C.A., Tozer, Daniel J., Duering, Marco, Malik, Rainer, Dichgans, Martin, Markus, Hugh S., Traylor, Matthew
Publikováno v:
Stroke 49(6), 1340-1347 (2018). doi:10.1161/STROKEAHA.118.020811
Stroke
Stroke
Supplemental Digital Content is available in the text.
Background and Purpose— Structural integrity of the white matter is a marker of cerebral small vessel disease, which is the major cause of vascular dementia and a quarter of all strokes. G
Background and Purpose— Structural integrity of the white matter is a marker of cerebral small vessel disease, which is the major cause of vascular dementia and a quarter of all strokes. G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::136cb45313d6590827a99e7dcc48c7b7
https://pub.dzne.de/record/139973
https://pub.dzne.de/record/139973
Autor:
Rutten-Jacobs, Loes Ca, Larsson, Susanna C, Malik, Rainer, Rannikmäe, Kristiina, MEGASTROKE Consortium, International Stroke Genetics Consortium, Sudlow, Cathie L, Dichgans, Martin, Markus, Hugh S, Traylor, Matthew
OBJECTIVE: To evaluate the associations of a polygenic risk score and healthy lifestyle with incident stroke. DESIGN: Prospective population based cohort study. SETTING: UK Biobank Study, UK. PARTICIPANTS: 306 473 men and women, aged 40-73 years, rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5741c6ecd215d1fa6644c44f09126fe
Autor:
Rutten-Jacobs, Loes Ca, Larsson, Susanna C, Malik, Rainer, Rannikmäe, Kristiina, MEGASTROKE consortium, International Stroke Genetics Consortium, Sudlow, Cathie L, Dichgans, Martin, Markus, Hugh S, Traylor, Matthew
Publikováno v:
The BMJ
The BMJ 363, k4168 (2018). doi:10.1136/bmj.k4168
The BMJ 363, k4168 (2018). doi:10.1136/bmj.k4168
Objective To evaluate the associations of a polygenic risk score and healthy lifestyle with incident stroke. Design Prospective population based cohort study. Setting UK Biobank Study, UK. Participants 306 473 men and women, aged 40-73 years, recruit
Autor:
Traylor, Matthew, Malik, Rainer, Nalls, Mike A, Cotlarciuc, Ioana, Radmanesh, Farid, Thorleifsson, Gudmar, Hanscombe, Ken B, Langefeld, Carl, Saleheen, Danish, Rost, Natalia S, Yet, Idil, Spector, Tim D, Bell, Jordana T, Hannon, Eilis, Mill, Jonathan, Chauhan, Ganesh, Debette, Stephanie, Bis, Joshua C, Longstreth, WT, Ikram, M Arfan, Launer, Lenore J, Seshadri, Sudha, METASTROKE, UK Young Lacunar DNA Study, NINDS Stroke Genetics Network, Neurology Working Group of the CHARGE Consortium, Hamilton-Bruce, Monica Anne, Jimenez-Conde, Jordi, Cole, John W, Schmidt, Reinhold, Słowik, Agnieszka, Lemmens, Robin, Lindgren, Arne, Melander, Olle, Grewal, Raji P, Sacco, Ralph L, Rundek, Tatjana, Rexrode, Kathryn, Arnett, Donna K, Johnson, Julie A, Benavente, Oscar R, Wasssertheil-Smoller, Sylvia, Lee, Jin-Moo, Pulit, Sara L, Wong, Quenna, Rich, Stephen S, de Bakker, Paul IW, McArdle, Patrick F, Woo, Daniel, Anderson, Christopher D, Xu, Huichun, Heitsch, Laura, Fornage, Myriam, Jern, Christina, Stefansson, Kari, Thorsteinsdottir, Unnur, Gretarsdottir, Solveig, Lewis, Cathryn M, Sharma, Pankaj, Sudlow, Cathie LM, Rothwell, Peter M, Boncoraglio, Giorgio B, Thijs, Vincent, Levi, Chris, Meschia, James F, Rosand, Jonathan, Kittner, Steven J, Mitchell, Braxton D, Dichgans, Martin, Worrall, Bradford B, Markus, Hugh S, International Stroke Genetics Consortium
OBJECTIVE: Genome-wide association studies (GWAS) have been successful at identifying associations with stroke and stroke subtypes, but have not yet identified any associations solely with small vessel stroke (SVS). SVS comprises one quarter of all i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______109::450df6492f38208db975b8dd021cb554
https://www.repository.cam.ac.uk/handle/1810/262766
https://www.repository.cam.ac.uk/handle/1810/262766
Autor:
Van Hemert, Albert M., Porteous, David J., O'Donovan, Michael C., McIntosh, Andrew M., Lewis, Glyn, Hayward, Caroline, Traylor, Matthew, Thomson, Pippa A., Tansey, Katherine E., Smith, Daniel J., Owen, Michael J., O'Reilly, Paul F., McGuffin, Peter, Marchini, Jonathan, MacIntyre, Donald J., Kretzschmar, Warren W., Hall, Lynsey S., Gaspar, Helena A., Escott-Price, Valentina, Eley, Thalia C., Deary, Ian J., Davies, Gail, Craddock, Nick, Coleman, Jonathan R.I., Clarke, Toni-Kim, Cai, Na, Blackwood, Douglas H.R., Adams, Mark J., Rivera, Margarita, Mullins, Niamh, Lewis, Cathryn, Kan, Carol, Dehghan, Abbas, Breen, Gerome, Sullivan, Patrick F., Borglum, Anders D., Levinson, Douglas F., Werge, Thomas, Weissman, Myrna M., Volzke, Henry, Uher, Rudolf, Tiemeier, Henning, Stefansson, Kari, Smoller, Jordan W., Schulze, Thomas G., Schaefer, Catherine, Potash, James B., Trubetskoy, Vassily, Treutlein, Jens, Thorgeirsson, Thorgeir E., Thompson, Wesley, Teismann, Henning, Steinberg, Stacy, Stefansson, Hreinn, Smit, Johannes H., Sinnamon, Grant C.B., Sigurdsson, Engilbert, Shyn, Stanley I., Shi, Jianxin, Shen, Ling, Schulte, Eva C., Schoevers, Robert, Mirza, Saira Saeed, Riley, Brien P., Rice, John P., Qvist, Per, Quiroz, Jorge A., Posthuma, Danielle, Pettersson, Erik, Peterson, Roseann E., Pedersen, Marianne Giortz, Pedersen, Carsten Bocker, Painter, Jodie N., Oskarsson, Hogni, Nyholt, Dale R., Nivard, Michel G., Ng, Bernard, Mostafavi, Sara, Montgomery, Grant W., Mondimore, Francis M., Milani, Lili, Mihailov, Evelin, Middeldorp, Christel M., Mehta, Divya, Medland, Sarah E., McGrath, Patrick, Mbarek, Hamdi, Maier, Wolfgang, Maier, Robert M., MacKinnon, Dean F., Lind, Penelope A., Li, Yihan, Kutalik, Zoltan, Krogh, Jesper, Kraft, Julia, Kohane, Isaac S., Knowles, James A., Jorgenson, Eric, Jansen, Rick, Ising, Marcus, Hougaard, David M., Hottenga, Jouke-Jan, Horn, Carsten, Hoffmann, Per, Hickie, Ian B., Herms, Stefan, Hansen, Thomas F., Hansen, Christine Soholm, Grove, Jakob, Gordon, Scott D., Goes, Fernando S., Frank, Josef, Finucane, Hilary K., Kiadeh, Farnush Farhadi Hassan, Dunn, Erin C., Dolan, Conor V., Direk, Nese, Derks, Eske M., Degenhardt, Franziska, Crawford, Gregory E., Couvy-Duchesne, Baptiste, Colodro-Conde, Lucia, Christensen, Jane Hvarregaard, Castelao, Enrique, Bybjerg-Grauholm, Jonas, Buttenschon, Henriette N., Bryois, Julien, Bigdeli, Tim B., Beekman, Aartjan T.F., Bakvad-Hansen, Marie, Bacanu, Silviu-Alin, Andlauer, Till F.M., Air, Tracy M., Agerbo, Esben, Abdellaoui, Abdel, Byrne, Enda M., Mattheisen, Manuel, Ripke, Stephan, Penninx, Brenda W.J.H., Boomsma, Dorret I., Wray, Naomi R., Van Der Auwera, Sandra, Teumer, Alexander, Strohmaier, Jana, Streit, Fabian, Rietschel, Marcella, Preisig, Martin, Pistis, Giorgio, Nauck, Matthias, Homuth, Georg, Grabe, Hans J., Forstner, Andreas J., Baune, Bernhard T., Peyrot, Wouter J., Lamers, Femke, Milaneschi, Yuri, Gill, Michael, Binder, Elisabeth B., Trzaskowski, Maciej, Perlis, Roy H., Pedersen, Nancy L., Paciga, Sara A., Nothen, Markus M., Nordentoft, Merete, Muller-Myhsok, Bertram, Mortensen, Preben Bo, Mors, Ole, Metspalu, Andres, Martin, Nicholas G., Magnusson, Patrik K., Madden, Pamela A.F., Lucae, Susanne, Li, Qingqin S., Kloiber, Stefan, Kendler, Kenneth S., Heath, Andrew C., Hamilton, Steven P., Esko, Tonu, Domschke, Katharina, Domenici, Enrico, DePaulo, J. Raymond, De Geus, E.J.C., Dannlowski, Udo, Cichon, Sven, Arolt, Volker, Zhang, Futao, Yang, Jian, Xi, Hualin S., Wu, Yang, Witt, Stephanie H., Willemsen, Gonneke, Wellmann, Jurgen, Weinsheimer, Shantel Marie, Webb, Bradley T., Wang, Yunpeng, Visscher, Peter M., Viktorin, Alexander, Umbricht, Daniel, Uitterlinden, Andre G., Berger, Klaus
Publikováno v:
Milaneschi, Y, Lamers, F, Peyrot, W J, Baune, B T, Breen, G, Dehghan, A, Forstner, A J, Grabe, H J, Homuth, G, Kan, C, Lewis, C, Mullins, N, Nauck, M, Pistis, G, Preisig, M, Rivera, M, Rietschel, M, Streit, F, Strohmaier, J, Teumer, A, Van der Auwera, S, Wray, N R, Boomsma, D I, Penninx, B W J H & CHARGE Inflammation Working Group and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2017, ' Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations ', J A M A Psychiatry, vol. 74, no. 12, pp. 1214-1225 . https://doi.org/10.1001/jamapsychiatry.2017.3016
Milaneschi, Y, Lamers, F, Peyrot, W J, Baune, B T, Breen, G, Dehghan, A, Forstner, A J, Grabe, H J, Homuth, G, Kan, C, Lewis, C, Mullins, N, Nauck, M, Pistis, G, Preisig, M, Rivera, M, Rietschel, M, Streit, F, Strohmaier, J, Teumer, A, Van der Auwera, S, Wray, N R, Boomsma, D I, Penninx, B W J H & CHARGE Inflammation Working Group and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2017, ' Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations ', JAMA Psychiatry, vol. 74, no. 12, pp. 1214-1225 . https://doi.org/10.1001/jamapsychiatry.2017.3016
JAMA psychiatry
2017, ' Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations ', JAMA Psychiatry . https://doi.org/10.1001/jamapsychiatry.2017.3016
JAMA Psychiatry, 74(12), 1214-1225. American Medical Association
Milaneschi, Y, Lamers, F, Peyrot, W J, Baune, B T, Breen, G, Dehghan, A, Forstner, A J, Grabe, H J, Homuth, G, Kan, C, Lewis, C M, Mullins, N, Nauck, M, Pistis, G, Preisig, M, Rivera, M, Rietschel, M, Streit, F, Strohmaier, J, Teumer, A, Van der Auwera, S, Wray, N R, Boomsma, D I, Penninx, B W J H & CHARGE Inflammation Working Group and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2017, ' Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations ', JAMA Psychiatry, vol. 74, no. 12, pp. 1214-1225 . https://doi.org/10.1001/jamapsychiatry.2017.3016
Milaneschi, Y, Lamers, F, Peyrot, W J, Baune, B T, Breen, G, Dehghan, A, Forstner, A J, Grabe, H J, Homuth, G, Kan, C, Lewis, C, Mullins, N, Nauck, M, Pistis, G, Preisig, M, Rivera, M, Rietschel, M, Streit, F, Strohmaier, J, Teumer, A, Van der Auwera, S, Wray, N R, Boomsma, D I, Penninx, B W J H & CHARGE Inflammation Working Group and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2017, ' Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations ', JAMA Psychiatry, vol. 74, no. 12, pp. 1214-1225 . https://doi.org/10.1001/jamapsychiatry.2017.3016
JAMA psychiatry
2017, ' Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations ', JAMA Psychiatry . https://doi.org/10.1001/jamapsychiatry.2017.3016
JAMA Psychiatry, 74(12), 1214-1225. American Medical Association
Milaneschi, Y, Lamers, F, Peyrot, W J, Baune, B T, Breen, G, Dehghan, A, Forstner, A J, Grabe, H J, Homuth, G, Kan, C, Lewis, C M, Mullins, N, Nauck, M, Pistis, G, Preisig, M, Rivera, M, Rietschel, M, Streit, F, Strohmaier, J, Teumer, A, Van der Auwera, S, Wray, N R, Boomsma, D I, Penninx, B W J H & CHARGE Inflammation Working Group and the Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium 2017, ' Genetic Association of Major Depression With Atypical Features and Obesity-Related Immunometabolic Dysregulations ', JAMA Psychiatry, vol. 74, no. 12, pp. 1214-1225 . https://doi.org/10.1001/jamapsychiatry.2017.3016
© 2017 American Medical Association. All rights reserved.IMPORTANCE The association between major depressive disorder (MDD) and obesitymay stem from shared immunometabolic mechanisms particularly evident in MDD with atypical features, characterized
OBJECTIVE We investigated whether oxidative phosphorylation (OXPHOS) abnormalities were associated with lacunar stroke, hypothesizing that these would be more strongly associated in patients with multiple lacunar infarcts and leukoaraiosis (LA). METH
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::717b41177b1cca553b76e5efb368b6d4
https://www.repository.cam.ac.uk/handle/1810/252835
https://www.repository.cam.ac.uk/handle/1810/252835