Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Rudolph L. Leibel"'
Autor:
Xiao Fan, Wendy K. Chung, Emily Breidbart, Rudolph L. Leibel, Jiancheng Guo, Patricia Lanzano, Charles A. LeDuc, Liyong Deng
Publikováno v:
J Pediatr Endocrinol Metab
Objectives There have been few large-scale studies utilizing exome sequencing for genetically undiagnosed maturity onset diabetes of the young (MODY), a monogenic form of diabetes that is under-recognized. We describe a cohort of 160 individuals with
Autor:
Rudolph L. Leibel, Steven R. Smith, Eric Ravussin, Juen Guo, Kevin D. Hall, Laurel S. Mayer, B. Timothy Walsh, Michael Rosenbaum, Marc L. Reitman
Publikováno v:
Obesity (Silver Spring, Md.)
Objective The objective of this study was to measure changes in glucose, lipid, and inflammation parameters after transitioning from a baseline diet (BD) to an isocaloric ketogenic diet (KD). Methods Glucose homeostasis, lipid homeostasis, and inflam
Autor:
Alpana P. Shukla, Elizabeth Shane, Rochelle L. Goldsmith, Wei Shen, Martica Heaner, Michael Rosenbaum, Elinor Naor, Rudolph L. Leibel, Louis J. Aronne, P. Christian Schulze
Publikováno v:
Obesity (Silver Spring, Md.)
Objective The objective of this study is to determine whether resistance training is similarly effective in reducing skeletal muscle efficiency and increasing strength in weight-reduced and maximal weight subjects. Methods This study examined the eff
Autor:
Robin Freyberg, Jeffrey A. Lieberman, Zachary Freyberg, Ignacio Contreras, Rudolph L. Leibel, Michael Rosenbaum, Utpal B. Pajvani, Laurel E.S. Mayer, Jacob S. Ballon
Publikováno v:
Journal of Psychopharmacology. 32:533-540
Second generation antipsychotics are prescribed for an increasing number of psychiatric conditions, despite variable associations with weight gain, dyslipidemia, and impaired glucose tolerance. The mechanism(s) of the apparent causal relationships be
Autor:
Mary K. Askren, Vidhi Tyagi, Susan J. Melhorn, Mary Rosalynn B. De Leon, Mario Kratz, Rudolph L. Leibel, Tyler A. Bosch, Wendy K. Chung, Thomas J. Grabowski, Mary F. Webb, Ellen A. Schur
Publikováno v:
The American Journal of Clinical Nutrition. 107:145-154
BACKGROUND: Variants in the first intron of the fat mass and obesity-associated (FTO) gene increase obesity risk. People with “high-risk” FTO genotypes exhibit preference for high-fat foods, reduced satiety responsiveness, and greater food intake
Autor:
Jingwei Cai, Qi Yan Ang, Michael Rosenbaum, Kevin D. Hall, Yuan Tian, Vaibhav Upadhyay, Rudolph L. Leibel, Margaret Alexander, Peter J. Turnbaugh, Eric Ravussin, Andrew D. Patterson, Eric Verdin, John C. Newman, Jessie A. Turnbaugh
Publikováno v:
Cell
Cell, vol 181, iss 6
Cell, vol 181, iss 6
Very low-carbohydrate, high-fat ketogenic diets (KDs) induce a pronounced shift in metabolic fuel utilization that elevates circulating ketone bodies; however, the consequences of these compounds for host-microbiome interactions remain unknown. Here,
Autor:
Michael Rosenbaum, Anne White, Rudolph L. Leibel, Richard M. Smiley, Sharon L. Wardlaw, Kana Meece, Gabrielle Page-Wilson
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 309:E458-E465
Leptin and its neuronal targets, which produce proopiomelanocortin (POMC) and agouti-related protein (AgRP), regulate energy balance. This study characterized leptin, POMC, and AgRP in the cerebrospinal fluid (CSF) of 47 healthy human subjects, 23 le
Autor:
Dympna Gallagher, Rochelle L. Goldsmith, Rudolph L. Leibel, Kenneth M. Baldwin, Michael Rosenbaum, Richard M. Smiley, Fadia Haddad
Publikováno v:
American journal of physiology. Endocrinology and metabolism. 315(5)
Subjects maintaining a ≥10% dietary weight loss exhibit decreased circulating concentrations of bioactive thyroid hormones and increased skeletal muscle work efficiency largely due to increased expression of more-efficient myosin heavy chain (MHC)
Publikováno v:
The American Journal of Clinical Nutrition. 100:996-1002
Background: The high prevalence of obesity has called attention to the near-intractable problem of sustained weight reduction and its underlying mechanisms. With diet-induced weight loss, achieved body weight is closely related to initial body weight
Autor:
Nianjun Liu, Rudolph L. Leibel, David B. Allison, Peng Li, Wan-Yu Lin, Hemant K. Tiwari, Nengjun Yi, Wendy K. Chung
Publikováno v:
International journal of obesity (2005)
Obesity, which is frequently associated with diabetes, hypertension and cardiovascular diseases, is primarily the result of a net excess of caloric intake over energy expenditure. Human obesity is highly heritable, but the specific genes mediating su