Zobrazeno 1 - 10
of 88
pro vyhledávání: '"Roger J. Packer"'
Autor:
Craig Erker, Adam Lane, Brooklyn Chaney, Sarah Leary, Jane E Minturn, Ute Bartels, Roger J Packer, Kathleen Dorris, Nicholas G Gottardo, Katherine E Warren, Alberto Broniscer, Mark W Kieran, Xiaoting Zhu, Peter White, Phillip J Dexheimer, Katie Black, Anthony Asher, Mariko DeWire, Jordan R Hansford, Sridharan Gururangan, Javad Nazarian, David S Ziegler, Eric Sandler, Allison Bartlett, Stewart Goldman, Chie-Schin Shih, Tim Hassall, Hetal Dholaria, Pratiti Bandopadhayay, Yvan Samson, Michelle Monje, Paul G Fisher, Andrew Dodgshun, Sarah Parkin, Murali Chintagumpala, Karen Tsui, David Gass, Valerie Larouche, Emmett Broxson, Mercedes Garcia Lombardi, Stacie Shiqi Wang, Jie Ma, Cynthia Hawkins, Dima Hamideh, Lars Wagner, Carl Koschmann, Christine Fuller, Rachid Drissi, Blaise V Jones, James Leach, Maryam Fouladi
Publikováno v:
Neuro Oncol
BackgroundDiffuse intrinsic pontine gliomas (DIPG) generally occur in young school-age children, although can occur in adolescents and young adults. The purpose of this study was to describe clinical, radiological, pathologic, and molecular character
Autor:
Javad Nazarian, Krutika S. Gaonkar, Naomi E. Rance, Cassie Kline, Maria-Magdalena Georgescu, Roger J. Packer, Maria I Almira-Suarez, Adam C. Resnick, Erin R. Bonner, Madhuri Kambhampati, Mojca Stampar, Sabine Mueller, Angela Waanders, Karim Saoud, Sridevi Yadavilli, Eshini Panditharatna, Yong Kim, Augustine Eze, Lindsay Kilburn, Jamila Gittens, Sulgi Lee, Courtney L. Johnson, Miriam Bornhorst, Lauren Hancock, Eugene Hwang, Brian R. Rood, Cheng-Ying Ho
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Scientific Reports
Scientific Reports
Children diagnosed with brain tumors have the lowest overall survival of all pediatric cancers. Recent molecular studies have resulted in the discovery of recurrent driver mutations in many pediatric brain tumors. However, despite these molecular adv
Autor:
Jaishri O. Blakeley, Cynthia Hawkins, Fausto J. Rodriguez, Stefan M. Pfister, Uri Tabori, Brian R. Rood, Antonio Iavarone, Roger J. Packer, Eric Bouffet, Tobey J. MacDonald, Stephen Albert Johnston, David T.W. Jones, Lindsay Kilburn, David H. Gutmann, Michael Fisher, Eugene Hwang, Yuan Zhu, Vijay Ramaswamy, Jason Fangusaro
Publikováno v:
Neuro-Oncology
Gliomas are the most common primary central nervous system tumors occurring in children and adults with neurofibromatosis type 1 (NF1). Over the past decade, discoveries of the molecular basis of low-grade gliomas (LGGs) have led to new approaches fo
Autor:
Catherine A. Billups, Timothy N. Booth, Paul A. Northcott, Stephanie M. Perkins, Jeff M. Michalski, Roger J. Packer, Karin M. Muraszko, Yimei Li, Kristina K. Hardy, Paul Colte, Yuanyuan Han, Rahul Kumar, Kyle S. Smith, Anna J. Janss, L. Gilbert Vezina, Nancy J. Tarbell, Leanne Embry, Maryam Fouladi, Peter C. Burger, Ian F. Pollack, Joel M. Cherlow, Johnnie K. Bass, Amar Gajjar, Patricia Cullen, Thomas J. Fitzgerald, Scott L. Pomeroy, Thomas E. Merchant, Jennifer Hadley
Publikováno v:
J Clin Oncol
PURPOSE Children with average-risk medulloblastoma (MB) experience survival rates of ≥ 80% at the expense of adverse consequences of treatment. Efforts to mitigate these effects include deintensification of craniospinal irradiation (CSI) dose and v
Autor:
Chie Emoto, Nathan Robison, Brigitte C. Widemann, Brian Weiss, Stewart Goldman, Jeffrey C. Allen, James H. Tonsgard, Alexander A. Vinks, Nancy Ratner, Michael Fisher, Jaishri O. Blakeley, Bruce R. Korf, Pamela L. Wolters, Coretta Thomas Robinson, Lloyd J. Edwards, Eva Dombi, Elizabeth K. Schorry, Scott R. Plotkin, Tsuyoshi Fukuda, Gary Cutter, Roger J. Packer
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 39(7)
PURPOSE Patients with neurofibromatosis type 1 (NF1) frequently develop plexiform neurofibromas (PNs), which can cause significant morbidity. We performed a phase II trial of the MAPK/ERK kinase inhibitor, mirdametinib (PD-0325901), in patients with
Autor:
Konstantin Okonechnikov, Charles G. Eberhart, Roger E. McLendon, Ian F. Pollack, Stefan M. Pfister, Kyle S. Smith, Shin Jung, Noriyuki Kijima, Alexandre Vasiljevic, Karisa C. Schreck, Oksana Absalyamova, Paul A. Northcott, Daniela Pretti da Cunha Tirapelli, Rajeev Vibhakar, Sarah Leary, Olga Zheludkova, Kay K.W. Li, Lakshmikirupa Sundaresan, Seung-Ki Kim, Hallie Coltin, Jaume Mora, Erwin G. Van Meir, Wiesława Grajkowska, Marcel Kool, Daniel W. Fults, Pim J. French, Caterina Giannini, Andreas von Deimling, Jennifer A. Chan, Andrey Golanov, Linda M. Liau, Scott Raskin, Michael D. Taylor, Joshua B. Rubin, Cécile Faure-Conter, Roger J. Packer, Luca Massimi, William A. Weiss, Peter Hauser, Andrey Korshunov, Lola B. Chambless, Patryk Skowron, Carlos Gilberto Carlotti, Vijay Ramaswamy, Marie Lise C. van Veelen, Marina Ryzhova, Damian Stichel, Nalin Gupta, Johan M. Kros
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Acta Neuropathologica, 142(5), 859-871. Springer-Verlag
ACTA NEUROPATHOLOGICA
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Universidade de São Paulo (USP)
instacron:USP
Acta Neuropathologica, 142(5), 859-871. Springer-Verlag
ACTA NEUROPATHOLOGICA
r-FSJD. Repositorio Institucional de Producción Científica de la Fundació Sant Joan de Déu
instname
Medulloblastoma, a common pediatric malignant central nervous system tumour, represent a small proportion of brain tumours in adults. Previously it has been shown that in adults, Sonic Hedgehog (SHH)-activated tumours predominate, with Wingless-type
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea6782957c4dce01ebe543e58d4aa048
Autor:
Nicole J. Ullrich, Stewart Goldman, Jeffrey C. Allen, Mark W. Kieran, Nathan Robison, Sanjay P. Prabhu, David H. Gutmann, Michael Fisher, Bruce R. Korf, David Viskochil, Roger J. Packer, John P. Perentesis
Publikováno v:
Pediatric Blood & Cancer. 68
Data for visual acuity (VA) after treatment of neurofibromatosis type 1-associated optic pathway gliomas (NF1-OPGs) are limited. We retrospectively collected VA, converted to logMAR, before and after targeted therapy with everolimus for NF1-OPG, and
Autor:
Matthias A. Karajannis, Jian Campian, Jaishri O. Blakeley, Michael Fisher, Gary Cutter, Roger J. Packer, Coretta Thomas, Tena Rosser, D. Wade Clapp, Scott R. Plotkin, Bruce R. Korf, Nicole J. Ullrich, Jeffrey C. Allen, Alona Muzikansky, James H. Tonsgard, Dan G. Duda
PURPOSE Bevacizumab treatment at 7.5 mg/kg every 3 weeks results in improved hearing in approximately 35%-40% of patients with neurofibromatosis type 2 (NF2) and progressive vestibular schwannomas (VSs). However, the optimal dose is unknown. In this
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91cb26c3d5b3d9662c99dc49e14b3af8
https://europepmc.org/articles/PMC7098833/
https://europepmc.org/articles/PMC7098833/
Autor:
David A. Solomon, Lindsay Kilburn, Cassie Kline, Anu Banerjee, Javad Nazarian, Payal Jain, Bo Zhang, Nathalene Truffaux, Joanna J. Phillips, Michael D. Prados, Sara A. Byron, Alison Roos, Kellie J. Nazemi, Sara Nasser, Sabine Mueller, Winnie S. Liang, Yuankun Zhu, Angela J. Waanders, John G. Kuhn, Michael E. Berens, Suresh N. Magge, John R. Crawford, Annette M. Molinaro, Roger J. Packer, Eshini Panditharatna, Adam C. Resnick, Nalin Gupta, Claudia Petritsch
Publikováno v:
International journal of cancer, vol 145, iss 7
Mueller, Sabine; Jain, Payal; Liang, Winnie S; Kilburn, Lindsay; Kline, Cassie; Gupta, Nalin; et al.(2019). A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium.. International journal of cancer. doi: 10.1002/ijc.32258. UCSF: Retrieved from: http://www.escholarship.org/uc/item/9b60x2n8
Mueller, Sabine; Jain, Payal; Liang, Winnie S; Kilburn, Lindsay; Kline, Cassie; Gupta, Nalin; et al.(2019). A pilot precision medicine trial for children with diffuse intrinsic pontine glioma-PNOC003: A report from the Pacific Pediatric Neuro-Oncology Consortium.. International journal of cancer. doi: 10.1002/ijc.32258. UCSF: Retrieved from: http://www.escholarship.org/uc/item/9b60x2n8
This clinical trial evaluated whether whole exome sequencing (WES) and RNA sequencing (RNAseq) of paired normal and tumor tissues could be incorporated into a personalized treatment plan for newly diagnosed patients (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2414e794b14e0994f75da1266c15d7d7
https://escholarship.org/uc/item/9b60x2n8
https://escholarship.org/uc/item/9b60x2n8
Autor:
Nicole J. Ullrich, Allison A. King, Leslie L. Robison, Kimberly Whelan, Roger J. Packer, Joseph P. Neglia, Kristy Seidel, Kevin R. Krull, Elizabeth Wells, Gregory T. Armstrong, Marilyn Stovall, Wendy M. Leisenring, Kevin C. Oeffinger, Charles A. Sklar, Lisa Diller
Publikováno v:
Neuro-Oncology. 20:132-142
Background Survivors of childhood central nervous system (CNS) tumors experience high rates of treatment-related neurologic sequelae. Whether survivors continue to be at increased risk for new events as they age is unknown. Methods Adverse neurologic