Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Jens, Bedke"'
Autor:
Toni K, Choueiri, Thomas, Powles, Mauricio, Burotto, Bernard, Escudier, Maria T, Bourlon, Bogdan, Zurawski, Victor M, Oyervides Juárez, James J, Hsieh, Umberto, Basso, Amishi Y, Shah, Cristina, Suárez, Alketa, Hamzaj, Jeffrey C, Goh, Carlos, Barrios, Martin, Richardet, Camillo, Porta, Rubén, Kowalyszyn, Juan P, Feregrino, Jakub, Żołnierek, David, Pook, Elizabeth R, Kessler, Yoshihiko, Tomita, Ryuichi, Mizuno, Jens, Bedke, Joshua, Zhang, Matthew A, Maurer, Burcin, Simsek, Flavia, Ejzykowicz, Gisela M, Schwab, Andrea B, Apolo, Robert J, Motzer, Suresh, Nair
Publikováno v:
New England Journal of Medicine. 384:829-841
The efficacy and safety of nivolumab plus cabozantinib as compared with those of sunitinib in the treatment of previously untreated advanced renal-cell carcinoma are not known.In this phase 3, randomized, open-label trial, we randomly assigned adults
Autor:
Thomas Powles, Piotr Tomczak, Se Hoon Park, Balaji Venugopal, Thomas Ferguson, Stefan N Symeonides, Jaroslav Hajek, Howard Gurney, Yen-Hwa Chang, Jae Lyun Lee, Naveed Sarwar, Antoine Thiery-Vuillemin, Marine Gross-Goupil, Mauricio Mahave, Naomi B Haas, Piotr Sawrycki, Joseph E Burgents, Lei Xu, Kentaro Imai, David I Quinn, Toni K Choueiri, Toni Choueiri, Thomas R. Ferguson, Tzu-Ping Lin, Stefan N. Symeonides, Naomi B. Haas, Howard P. Gurney, Christine Chevreau, John M. Burke, Gurjyot Doshi, Bohuslav Melichar, Delphine Topart, Stephane Oudard, Evgeniy Kopyltsov, Hans-Joerg Hammers, David I. Quinn, Ajjai Alva, Juliana de Janoski Menezes, Adriano Goncalves e Silva, Eric W. Winquist, Alketa Hamzaj, Giuseppe Procopio, Boguslawa Karaszewska, Ewa M. Nowakowska-Zajdel, Boris Y. Alekseev, Rustem A. Gafanov, Adel Izmailov, Andrey Semenov, Sergey G. Afanasyev, Oleg N. Lipatov, Thomas B. Powles, Sandy Srinivas, David McDermott, Samith T. Kochuparambil, Ian D. Davis, Katriina Peltola, Roberto Sabbatini, Jinsoo Chung, Michail I. Shkolnik, Vsevolod B. Matveev, Pablo Gajate Borau, Steven McCune, Thomas E. Hutson, Alejandro Dri, Silvio Correia Sales, Carrie Yeung, Carmen Marcela Alcala Castro, Peter Bostrom, Brigitte Laguerre, Consuelo Buttigliero, Ugo de Giorgi, Eugeniy A. Fomin, Yousef Zakharia, Clara Hwang, Eric A. Singer, Jeffrey T. Yorio, David Waterhouse, Ruben Dario Kowalyszyn, Margarita Sonia Alfie, Eduardo Yanez Ruiz, Tomas Buchler, Krista Kankaanranta, Gianluigi Ferretti, Go Kimura, Kazuo Nishimura, Naoya Masumori, Satoshi Tamada, Haruaki Kato, Hiroshi Kitamura, Iwona Danielewicz, Joanna Wojcik-Tomaszewska, Nuria Sala Gonzalez, Kun-Yuan Chiu, Michael B. Atkins, Elisabeth Heath, Gustavo Adolfo Rojas-Uribe, Manuel Enrique Gonzalez Fernandez, Susan Feyerabend, Sandro Pignata, Kazuyuki Numakura, Bozena Cybulska Stopa, Ruslan Zukov, Miguel Angel Climent Duran, Pablo Jose Maroto Rey, Alvaro Montesa Pino, Chao-Hsiang Chang, Salil Vengalil, Tom S. Waddell, Patrick W. Cobb, Ralph Hauke, Daniel M. Anderson, John Sarantopoulos, Theodore Gourdin, Tian Zhang, Gautam Jayram, Luis Enrique Fein, Carole Harris, Patricia Medeiros Milhomem Beato, Francisco Flores, Angela Estay, Juan Andres Rubiano, Jens Bedke, Stefan Hauser, Andreas Neisius, Jonas Busch, Satoshi Anai, Hiroyuki Tsunemori, Dariusz Sawka, Bozena Sikora-Kupis, Jose Angel Arranz, Ignacio Delgado, Chung-Hsin Chen, Elizabeth Gunderson, Scott Tykodi, Alan Koletsky, Kevin Chen, Manish Agrawal, Diego Lucas Kaen, Juan Pablo Sade, Marcelo Daniel Tatangelo, Francis Parnis, Fernando Maciel Barbosa, Genevieve Faucher, Nayyer Iqbal, Daniele Marceau, Jean-Benoit Paradis, Nawar Hanna, Alejandro Acevedo, Carolina Ibanez, Luis Villanueva, Pedro Pablo Galaz, Isabel Cristina Durango, Ray Manneh, Zdenek - Kral, Petra Holeckova, Heikki Hakkarainen, Hanna Ronkainen, Sophie Abadie-Lacourtoisie, Sophie Tartas, Peter J. Goebell, Marc-Oliver Grimm, Thomas Hoefner, Manfred Wirth, Andrej Panic, Wolfgang Schultze-Seemann, Akira Yokomizo, Ryuichi Mizuno, Hirotsugu Uemura, Masatoshi Eto, Masao Tsujihata, Yoshihisa Matsukawa, Yoji Murakami, Miso Kim, Paul Hamberg, Malgorzata Marczewska-Skrodzka, Cezary Szczylik, Alison C. Humphreys, Peter Jiang, Birendra Kumar, Gary Lu, Arpita Desai, Jose Antonio Karam, George Keogh, Mark Fleming, Juan Jose Zarba, Viviana E. Leiva, Guillermo Ariel Mendez, Samuel J. Harris, Stephen J. Brown, Joao Neif Antonio Junior, Rita de Cassia Costamilan, Roberto Odebrecht Rocha, David Muniz, Leandro Brust, Aly-Khan Lalani, Jeffrey Graham, Michael Levesque, Francisco Orlandi, Rostislav Kotasek, Jean L. Deville, Delphine Borchiellini, Axel Merseburger, Michael Rink, Frederik Roos, Ray McDermott, Masafumi Oyama, Yoshiaki Yamamoto, Yoshihiko Tomita, Yuji Miura, Naomasa Ioritani, Hans Westgeest, Tomasz Kubiatowski, Wieslaw Bal, Regina Girones Sarrio, Julie Rowe, Debra M. Prow, Francis Senecal, Neda Hashemi-Sadraei, Scott W. Cole, Stephan D. Kendall, Donald A. Richards, Ian D. Schnadig, Mukul Gupta
Publikováno v:
2022, ' Pembrolizumab versus placebo as post-nephrectomy adjuvant therapy for clear cell renal cell carcinoma (KEYNOTE-564): 30-month follow-up analysis of a multicentre, randomised, double-blind, placebo-controlled, phase 3 trial ', The Lancet Oncology, vol. 23, no. 9, pp. 1133-1144 . https://doi.org/10.1016/S1470-2045(22)00487-9
Background: The first interim analysis of the KEYNOTE-564 study showed improved disease-free survival with adjuvant pembrolizumab compared with placebo after surgery in patients with clear cell renal cell carcinoma at an increased risk of recurrence.
Publikováno v:
World Journal of Urology
Purpose The 7th TNM classification summarizes renal cell carcinoma (RCC) with perirenal (PFI) and/or sinus fat invasion (SFI) as well as hilar vein involvement (RVI) as pT3a tumors. In this study, we aimed to determine the prognostic value of fat inv
Autor:
Inês Anselmo da Costa, Jörg Hennenlotter, Julian Mayer, Susanne Deininger, Stephan Kruck, Eva Neumann, Niklas Harland, Arnulf Stenzl, Bastian Amend, Giorgio I. Russo, Steffen Rausch, Jens Bedke
Publikováno v:
European Urology Focus. 5:906-911
Background The number of virtual reality (VR) simulators is increasing. The aim of this prospective trial was to determine the benefit of VR cystoscopy (UC) and transurethral bladder tumor resection (TURBT) training in students. Design, setting, and
Autor:
Toni K, Choueiri, Piotr, Tomczak, Se Hoon, Park, Balaji, Venugopal, Thomas, Ferguson, Yen-Hwa, Chang, Jaroslav, Hajek, Stefan N, Symeonides, Jae Lyun, Lee, Naveed, Sarwar, Antoine, Thiery-Vuillemin, Marine, Gross-Goupil, Mauricio, Mahave, Naomi B, Haas, Piotr, Sawrycki, Howard, Gurney, Christine, Chevreau, Bohuslav, Melichar, Evgeniy, Kopyltsov, Ajjai, Alva, John M, Burke, Gurjyot, Doshi, Delphine, Topart, Stephane, Oudard, Hans, Hammers, Hiroshi, Kitamura, Jens, Bedke, Rodolfo F, Perini, Pingye, Zhang, Kentaro, Imai, Jaqueline, Willemann-Rogerio, David I, Quinn, Thomas, Powles, KyungMann, Kim
Publikováno v:
Choueiri, T K, Tomczak, P, Park, S H, Venugopal, B, Ferguson, T, Chang, Y, Hajek, J, Symeonides, S N, Lee, J L, Sarwar, N, Thiery-vuillemin, A, Gross-goupil, M, Mahave, M, Haas, N B, Sawrycki, P, Gurney, H, Chevreau, C, Melichar, B, Kopyltsov, E, Alva, A, Burke, J M, Doshi, G, Topart, D, Oudard, S, Hammers, H, Kitamura, H, Bedke, J, Perini, R F, Zhang, P, Imai, K, Willemann-rogerio, J, Quinn, D I & Powles, T 2021, ' Adjuvant Pembrolizumab after Nephrectomy in Renal-Cell Carcinoma ', New England Journal of Medicine, vol. 385, no. 8, pp. 683-694 . https://doi.org/10.1056/NEJMoa2106391
Patients with renal-cell carcinoma who undergo nephrectomy have no options for adjuvant therapy to reduce the risk of recurrence that have high levels of supporting evidence.In a double-blind, phase 3 trial, we randomly assigned, in a 1:1 ratio, pati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d551e4fc79d83dc49b7978a45e00010
https://www.pure.ed.ac.uk/ws/files/223344949/nejmoa2106391.pdf
https://www.pure.ed.ac.uk/ws/files/223344949/nejmoa2106391.pdf
Autor:
Jens Bedke, Judith Wahrheit, Marcus Scharpf, Anna Reustle, Matthias Schwab, Elke Schaeffeler, Abbas Agaimy, Arndt Hartmann, Verena Klumpp, Steffen Rausch, Arnulf Stenzl, Stefan Winter, Pascale Fisel, Florian Büttner, Falko Fend, Jörg Hennenlotter, Denise Sonntag, Stephan Kruck
Publikováno v:
European Urology Focus. 5:608-618
Background Renal cell carcinoma (RCC) consists of prognostic distinct subtypes derived from different cells of origin (eg, clear cell RCC [ccRCC], papillary RCC [papRCC], and chromophobe RCC [chRCC]). ccRCC is characterized by lipid accumulation and
Autor:
Steffen Rausch, Jörg Hennenlotter, Elke Schaeffeler, Matthias Schwab, Stephan Kruck, Falko Fend, Peter Klaiber, Eva Neumann, Jens Bedke, Kathleen Freitag, Arnulf Stenzl, Marcus Scharpf
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 145:1835-1843
Based on the observation of beneficial effects on cancer metabolism, microenvironment, or VEGF-signaling, several non-anticancer drugs have been discussed as useful in renal cell carcinoma (RCC). In the present study, we investigated the prognostic i
Autor:
Arnulf Stenzl, Konstantin Nikolaou, Marius Horger, Stephan Kruck, Wolfgang M. Thaiss, Jens Bedke, Sascha Kaufmann, Daniel Spira
Publikováno v:
World Journal of Urology. 37:1339-1346
To prospectively characterize computed tomography (CT)-indeterminate renal masses (CTIRM) using acoustic radiation force impulse (ARFI) elastography and contrast-enhanced ultrasound (CEUS) and to correlate quantitative imaging findings with histopath
Autor:
Jens Bedke, Oliver Rick, Heinrich Recken, Hans Ulrich Schmelz, Stefan Schweyer, Stefanie Seeling, Susanne Krege, Timur Ohloff, Sabine Kliesch, Thorsten Diemer, Johannes Classen, K. Oechsle, Christoph Oing, Christian Ruf, Julia Heinzelbecker, Matthias Gockel, Ulrich Otto, Maike de Wit, Christian Wittekind, Stefanie Schmidt, Rainer Souchon, Marko Kornmann, Arndt-Christian Müller, Renate Pichler, Anja Lorch, Friedemann Zengerling, Glen Kristiansen, Roger Zillmann, Jörg Kotzerke, Clemens Aigner, Axel Heidenreich, Peter Albers, Christian Winter, Carsten Bokemeyer, Walter Albrecht, Sascha Kaufmann, David Pfister, Mark Schrader, Thomas Hermanns, Bernt Göckel-Beining, Heinz Schmidberger, Yvonne Rudolph, Kathleen Herkommer, Dirk Beyersdorff, Klaus-Peter Dieckmann, Doris Wilborn, Anette Dieing, Oliver W. Hakenberg, Jonas Busch, Matthias Beintker, Dirk-Henrik Zermann, Joachim Schirren
Publikováno v:
Urol Int
Objectives: We developed the first German evidence- and consensus-based clinical guideline on diagnosis, treatment, and follow-up of germ cell tumours (GCT) of the testes in adult patients. We present the guideline content in 2 separate publications.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13b2bdc5a099705fb1243250f4b4fa6f
https://europepmc.org/articles/PMC8006578/
https://europepmc.org/articles/PMC8006578/
Autor:
Rainer Souchon, Anja Lorch, Oliver W. Hakenberg, Renate Pichler, Oliver Rick, Jonas Busch, Matthias Beintker, Stefanie Schmidt, Heinz Schmidberger, Kathleen Herkommer, Joachim Schirren, Dirk Beyersdorff, Klaus-Peter Dieckmann, Christoph Oing, Julia Heinzelbecker, Johannes Classen, Susanne Krege, Timur Ohloff, Stefan Schweyer, Ulrich Otto, Glen Kristiansen, Sabine Kliesch, Jörg Kotzerke, Heinrich Recken, Christian Winter, Stefanie Seeling, Doris Wilborn, Christian Wittekind, Peter Albers, Christian Ruf, Hans Ulrich Schmelz, Matthias Gockel, Walter Albrecht, Thomas Hermanns, Maike de Wit, Bernt Göckel-Beining, Thorsten Diemer, Arndt-Christian Müller, K. Oechsle, David Pfister, Dirk-Henrik Zermann, Roger Zillmann, Marko Kornmann, Axel Heidenreich, Clemens Aigner, Friedemann Zengerling, Carsten Bokemeyer, Sascha Kaufmann, Mark Schrader, Anette Dieing, Yvonne Rudolph, Jens Bedke
Publikováno v:
Urol Int
Introduction: This is the first German evidence- and consensus-based clinical guideline on diagnosis, treatment, and follow-up on germ cell tumours (GCTs) of the testis in adult patients. We present the guideline content in two publications. Part I c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0535ed018011c9aac4a56476eaf496ef
https://mediatum.ub.tum.de/1638010
https://mediatum.ub.tum.de/1638010