Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Christoph Walz"'
Autor:
Razieh Khoshnevisan, Roya Sherkat, Katrin Schröder, Franziska Moll, Michael W. Anderson, Christoph Walz, Scott B. Snapper, Sebastian Hollizeck, Alireza Andalib, Meino Rohlfs, Daniel Kotlarz, Sierra Anderson, Christoph Klein, Abbas Rezaei, David Illig, Peyman Adibi, S. Koletzko, Stephen Babcock, Benjamin Marquardt, Jay R. Thiagarajah, Aleixo M. Muise
Publikováno v:
Inflamm Bowel Dis
Background Genetic defects of pediatric-onset inflammatory bowel disease (IBD) provide critical insights into molecular factors controlling intestinal homeostasis. NOX1 has been recently recognized as a major source of reactive oxygen species (ROS) i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d048923cbf3022224f45efb31758b0f
https://europepmc.org/articles/PMC7365810/
https://europepmc.org/articles/PMC7365810/
Autor:
Anne K. Klenk, Christoph Klein, Irene Schmid, Michael H. Albert, Fabian Hauck, Sibylle Koletzko, Bernd H. Belohradsky, Christoph Walz, Horst von Bernuth, Philip Bufler
Publikováno v:
Journal of Crohn's and Colitis. 10:112-115
Background and Aims: X-linked chronic granulomatous disease [X-CGD] due to hemizygous mutations in CYBB is characterised by invasive bacterial and fungal infections and granulomatous inflammation. Inflammatory bowel disease [IBD] is an additional or
Autor:
Franziska Ruëff, Christoph Walz, Karl Sotlar, Roswitha Kerler, Sabina Berezowska, Hans-Peter Horny, Michael J. Flaig, Torsten Haferlach, Manuela Krokowski, Karina Petat-Dutter
Publikováno v:
Modern Pathology. 27:19-29
Adult-onset urticaria pigmentosa/mastocytosis in the skin almost always persists throughout life. The prevalence of systemic mastocytosis in such patients is not precisely known. Bone marrow biopsies from 59 patients with mastocytosis in the skin and
Autor:
Martina Teichmann, Torsten Haferlach, Mohamad Jawhar, Andreas Reiter, Manja Meggendorfer, Peter Valent, Georgia Metzgeroth, Vera Grossmann, Andreas Hochhaus, Nicholas C.P. Cross, Alice Fabarius, Christoph Walz, Hans-Peter Horny, Susanne Schnittger, Philipp Erben, Alexander Kohlmann, Thomas Ernst, Markus Pfirrmann, Juliana Schwaab, Karl Sotlar, Wolf-Karsten Hofmann
Publikováno v:
Blood. 122:2460-2466
To explore mechanisms contributing to the clinical heterogeneity of systemic mastocytosis (SM) and to suboptimal responses to diverse therapies, we analyzed 39 KIT D816V mutated patients with indolent SM (n = 10), smoldering SM (n = 2), SM with assoc
Autor:
Jürgen Mix, Philipp Erben, Francesco del Valle, Jelena Reinhard, Nicholas C.P. Cross, Darko Gosenca, Claudia Haferlach, Georgia Metzgeroth, Thomas Ernst, Andreas Reiter, Joannah Score, Andreas Hochhaus, Martin Müller, Christoph Walz
Publikováno v:
Haematologica. 95:738-744
Background Rapid identification of diverse fusion genes with involvement of PDGFRA or PDGFRB in eosinophilia-associated myeloproliferative neoplasms is essential for adequate clinical management but is complicated by the multitude and heterogeneity o
Autor:
David Grimwade, Riidiger Hehlmann, Christoph Walz, Claudia Haferlach, Philipp Erben, Annette Schmitt-Graeff, Alice Fabarius, Helena Popp, Andreas Reiter, Georgia Metzgeroth, Susanne Schnittger, Nicholas C.P. Cross, Andreas Hochhaus
Publikováno v:
British Journal of Haematology. 143:707-715
This study evaluated the efficacy and safety of imatinib in chronic eosinophilic leukaemia (CEL, n = 23) and hypereosinophilic syndrome (HES, n = 13). In CEL with FIP1L1-PDGFRA (n = 16) or various PDGFRB fusion genes (n = 5), complete haematological
The t(8;9)(p22;p24) Is a Recurrent Abnormality in Chronic and Acute Leukemia that Fuses PCM1 to JAK2
Autor:
Nick Telford, Rüdiger Hehlmann, Andreas Reiter, Brigitte Schlegelberger, Ute Berger, Danny Vanstraelen, Cornelia Rudolph, Hans-Jochem Kolb, Ilona Blau, Shilani Aruliah, John A Yin, Christoph Walz, Peter C Taylor, Helen F Barker, Claudia Schoch, Aisling O'Driscoll, Ann E. Watmore, Andreas Hochhaus, Nicholas C.P. Cross, Andrew Chase, Fabio Benedetti
Publikováno v:
Cancer Research. 65:2662-2667
We have identified a t(8;9)(p21-23;p23-24) in seven male patients (mean age 50, range 32-74) with diverse hematologic malignancies and clinical outcomes: atypical chronic myeloid leukemia/chronic eosinophilic leukemia (n = 5), secondary acute myeloid
Autor:
Andreas Hochhaus, Elisabeth Märker-Hermann, Andreas Reiter, Christoph Walz, Heidi Bauer, Norbert Frickhofen, Bernd Jung
Publikováno v:
Annals of Hematology. 83:477-480
Many cases of hypereosinophilia, formerly classified as hypereosinophilic syndrome, can now be characterized as chronic eosinophilic leukemia (CEL) based on the demonstration of characteristic genetic markers indicating clonality of hematopoiesis. He
Autor:
S. Mousset, Wolf-K. Hofmann, Christoph Walz, Nicholas C.P. Cross, T. Klippstein, Andreas Hochhaus, Georgia Metzgeroth, Martina Teichmann, Helen J. Martin, Andreas Reiter, Philipp Erben
Publikováno v:
Leukemia. 26:162-164
Limited clinical activity of nilotinib and sorafenib in FIP1L1-PDGFRA positive chronic eosinophilic leukemia with imatinib-resistant T674I mutation
Autor:
Eva Maria Putz, Peter Valent, Angelika Berger, Matthias Mayerhofer, Karl Sotlar, Konrad Hoetzenecker, Veronika Sexl, Karoline V. Gleixner, Andreas Reiter, Christoph Walz, Sabine Cerny-Reiterer, Georg Greiner, Gregor Hoermann, Katharina Blatt, Leonhard Müllauer, Harald Herrmann
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28(8)
Advanced systemic mastocytosis (SM) is an aggressive hematopoietic neoplasm with poor prognosis and short survival times. So far, no curative therapy is available for affected patients. We have identified the cell surface antigen CD52 (CAMPATH-1) as