Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Anna Mae Diehl"'
Autor:
Cynthia D. Guy, Ying Wang, Anna Mae Diehl, Dana Portenier, Dawn Piercy, Matthew J Crowley, Andrea D. Coviello, Anastasia-Stefania Alexopoulos, Ranjan Sudan, Cynthia A. Moylan, Manal F. Abdelmalek, Keri A. Seymour, Ricardo Henao
Publikováno v:
Hepatology (Baltimore, Md.). 74(3)
BACKGROUND AND AIMS Whether glycemic control, as opposed to diabetes status, is associated with the severity of NAFLD is open for study. We aimed to evaluate whether degree of glycemic control in the years preceding liver biopsy predicts the histolog
Autor:
Tinsay A, Woreta, Mark L, Van Natta, Mariana, Lazo, Arunkumar, Krishnan, Brent A, Neuschwander-Tetri, Rohit, Loomba, Anna, Mae Diehl, Manal F, Abdelmalek, Naga, Chalasani, Samer, Gawrieh, Srinivasan, Dasarathy, Raj, Vuppalanchi, Mohammad S, Siddiqui, Kris V, Kowdley, Arthur, McCullough, Norah A, Terrault, Cynthia, Behling, David E, Kleiner, Mark, Fishbein, Paula, Hertel, Laura A, Wilson, Emily P, Mitchell, Laura A, Miriel, Jeanne M, Clark, James, Tonascia, Arun J, Sanyal
Publikováno v:
PLOS ONE. 17:e0266859
Background and aims Management of patients with NASH who are at elevated risk of progressing to complications of cirrhosis (at-risk NASH) would be enhanced by an accurate, noninvasive diagnostic test. The new FAST™ score, a combination of FibroScan
Autor:
Andrea G. Nackley, Wolfgang Liedtke, Anna Mae Diehl, Huiping Ding, Andreas E. Kremer, Johannes Morstein, Ana E. López-Romero, Qian Zeng, Zilong Wang, Ru-Rong Ji, Qiaojuan Zhang, Yong Chen, Xin Zhang, Piotr Milkiewicz, Tony E. Reeves, Sara L. Morales-Lázaro, Jennifer Y. Zhang, Marcin Krawczyk, Tamara Rosenbaum, Mei-Chuan Ko, Frank Lammert, Andrey V. Bortsov, Manal F. Abdelmalek, Michele Yeo, Huanghe Yang, Carlene Moore, Ying-Ai Jin
Publikováno v:
Gastroenterology. 161(1)
Background & Aims Limited understanding of pruritus mechanisms in cholestatic liver diseases hinders development of antipruritic treatments. Previous studies implicated lysophosphatidic acid (LPA) as a potential mediator of cholestatic pruritus. Meth
Autor:
Clemence M, Canivet, Norma, David, Helene, Pailhoriès, Martial, Briand, Cynthia D, Guy, Olivier, Bouchez, Gilles, Hunault, Lionel, Fizanne, Adrien, Lannes, Frederic, Oberti, Isabelle, Fouchard, Paul, Calès, Anna Mae, Diehl, Matthieu, Barret, Jerome, Boursier
Publikováno v:
Alimentary pharmacologytherapeuticsREFERENCES. 53(6)
The reconstruction of metagenome-assembled genomes (MAGs) has emerged as a powerful approach for combining the taxonomic and functional content of microbial populations.To use this new approach to highlight mechanisms linking gut microbiota to NAFLD
Publikováno v:
Nature metabolism. 1(11)
Autor:
Ying Wang, Cynthia D. Guy, Cynthia A. Moylan, Anna Mae Diehl, Catherine F. Howe, Manal F. Abdelmalek, Ricardo Henao, Kara Wegermann
Publikováno v:
Hepatology Communications
Hepatology Communications, Vol 5, Iss 4, Pp 608-617 (2021)
Hepatology Communications, Vol 5, Iss 4, Pp 608-617 (2021)
Identifying patients at higher risk for poor outcomes from nonalcoholic fatty liver disease (NAFLD) remains challenging. Metabolomics, the comprehensive measurement of small molecules in biological samples, has the potential to reveal novel noninvasi
Autor:
Mustafa R. Bashir, David A. Rizzieri, Keith M. Sullivan, Mohammad Chaudhry, Louis F. Diehl, Mitchell E. Horwitz, Ko K. Maung, Kristi Romero, Anna Mae Diehl, Kelly Corbet, Anthony D. Sung, Stefanie Sarantopoulos, Richard D. Lopez, Sendhilnathan Ramalingam, Yi Ren, Cristina Gasparetto, Gwynn D. Long, Sin-Ho Jung, Taewoong Choi, Nelson J. Chao
Publikováno v:
PLoS ONE
PLoS ONE, Vol 15, Iss 9, p e0238824 (2020)
PLoS ONE, Vol 15, Iss 9, p e0238824 (2020)
Allogeneic-HCT (allo-HCT), while potentially curative, can result in significant complications including graft versus host disease (GVHD). Prior studies suggest that metabolic syndrome may be one risk factor for GVHD. We hypothesized that hepatic ste
Autor:
Manal F. Abdelmalek, Richard T. Premont, Jeongeun Hyun, Mustafa R. Bashir, Cynthia A. Moylan, Kuo Du, Satish K. Chitneni, Ricardo Henao, Ayako Suzuki, Ying Wang, Anna Mae Diehl, Susanna Naggie
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 1-21 (2020)
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 1-21 (2020)
Background & Aims Nonalcoholic steatohepatitis (NASH) occurs in the context of aberrant metabolism. Glutaminolysis is required for metabolic reprograming of hepatic stellate cells (HSCs) and liver fibrogenesis in mice. However, it is unclear how chan
Autor:
Rohit, Loomba, Brent A, Neuschwander-Tetri, Arun, Sanyal, Naga, Chalasani, Anna Mae, Diehl, Norah, Terrault, Kris, Kowdley, Srinivasan, Dasarathy, David, Kleiner, Cynthia, Behling, Joel, Lavine, Mark, Van Natta, Michael, Middleton, James, Tonascia, Claude, Sirlin, Tanya, Wolfson
Publikováno v:
Hepatology
BACKGROUND AND AIMS Emerging data from a single-center study suggests that a 30% relative reduction in liver fat content as assessed by magnetic resonance imaging-proton density fat fraction (MRI-PDFF) from baseline may be associated with histologic
Autor:
Elizabeth M. Brunt, Ryan M. Gill, Norah A. Terrault, Patricia Belt, Anna Mae Diehl, Brent A. Neuschwander-Tetri, Srinivasan Dasarathy, Oscar W. Cummings, Matthew M. Yeh, Cynthia Behling, Kris V. Kowdley, Cynthia D. Guy, Arun J. Sanyal, James Tonascia, Laura Wilson, David E. Kleiner, Melissa J. Contos, Rohit Loomba, Naga Chalasani, Joel E. Lavine
Publikováno v:
JAMA Network Open
Key Points Question In patients with nonalcoholic fatty liver disease who are not undergoing specific therapeutic interventions, what factors are associated with progression and regression of hepatic fibrosis? Findings In this cohort study of 446 pat