Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Ena Wang"'
Autor:
Yuri Kotliarov, Nancy F. Hensel, Jinguo Chen, Catherine M. Bollard, Neal S. Young, J. Joseph Melenhorst, Kazushi Tanimoto, Minoo Battiwalla, Foo Cheung, A. John Barrett, Angelique Biancotto, Sawa Ito, Mattias Carlsten, Ena Wang, Zhi Xie, Shira Perl, Keyvan Keyvanfar, Pawel Muranski, Paula Schum, Thomas E. Hughes, Matthew J. Olnes, Francesco M. Marincola
Publikováno v:
Molecular Therapy. 22:1388-1395
Low-dose interleukin-2 (IL-2) expands regulatory T cells (Tregs) and natural killer (NK) cells after stem cell transplantation (SCT) and may reduce graft-versus-host disease (GVHD). We hypothesized that ultra-low dose (ULD) IL-2 could serve as an imm
Autor:
Yingdong Zhao, William W. Grosh, Geoffrey R. Weiss, Ena Wang, Craig L. Slingluff, Hui Liu, Kimberly A. Chianese-Bullock, Francesco M. Marincola
Publikováno v:
Clinical Cancer Research. 17:7440-7450
Purpose: We have previously shown that within tumors, recombinant interleukin-2 (rIL-2, aldesleukin) consistently activates tumor-associated macrophages and upregulates IFN-stimulated genes while inducing minimal migration, activation, or proliferati
Autor:
Monica C. Panelli, Dae Won Kim, Seunghee Kim-Schulze, David F. Stroncek, Marianna Sabatino, Ena Wang, Gail DeRaffele, Zoltan Pos, Francesco M. Marincola, Bret Taback, Howard L. Kaufman
Publikováno v:
Journal of Clinical Oncology. 27:2645-2652
Purpose High-dose interleukin-2 (IL-2) induces durable therapeutic responses in a small subset of patients with metastatic melanoma and renal cell carcinoma, but simple pretreatment predictors of response have not been identified. Patients and Method
Autor:
Shira Perl, Angelique Biancotto, J. Christopher Fuchs, Marc Langweiler, Abigail Wank, Wendell Cook, Ena Wang, Pradeep K. Dagur, J. Philip McCoy, Matthew J. Olnes
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 12, p e76091 (2013)
PLoS ONE, Vol 8, Iss 12, p e76091 (2013)
Background Cytokines are humoral molecules that elicit regulatory function in immunologic pathways. The level and type of cytokine production has become critical in distinguishing physiologic from pathologic immune conditions. Cytokine profiling has
Autor:
Davide Bedognetti, Qiuzhen Liu, Tara L Spivey, S. A. Rosenberg, Lorenzo Uccellini, Yingdong Zhao, Maria Libera Ascierto, M. E. Dudley, Mario Roberto Sertoli, V. De Giorgi, Michele Sommariva, Ena Wang, Lucia Gemma Delogu, Francesco M. Marincola, Richard Simon, Sara Tomei
Publikováno v:
British Journal of Cancer
Background: Adoptive therapy with tumour-infiltrating lymphocytes (TILs) induces durable complete responses (CR) in ∼20% of patients with metastatic melanoma. The recruitment of T cells through CXCR3/CCR5 chemokine ligands is critical for immune-me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50ad0079034a467b24ffb9e34e76831c
http://hdl.handle.net/11567/799008
http://hdl.handle.net/11567/799008
Autor:
Francesco M. Marincola, John R. Wunderlich, Justin Jeffries, Monica C. Panelli, Ena Wang, Arnold Mixon, Steven A. Rosenberg
Publikováno v:
Journal of immunotherapy (Hagerstown, Md. : 1997). 23(4)
Dendritic cells (DCs) have been shown to enhance anti-tumor immune responses in several preclinical models. Furthermore, DC-like function can be elicited from peripheral blood monocytes cultured in vitro with interleukin-4 and granulocyte-macrophage