Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ben Goldacre"'
Autor:
Elsie M F Horne, William J Hulme, Ruth H Keogh, Tom M Palmer, Elizabeth J Williamson, Edward P K Parker, Amelia Green, Venexia Walker, Alex J Walker, Helen Curtis, Louis Fisher, Brian MacKenna, Richard Croker, Lisa Hopcroft, Robin Y Park, Jon Massey, Jessica Morley, Amir Mehrkar, Sebastian Bacon, David Evans, Peter Inglesby, Caroline E Morton, George Hickman, Simon Davy, Tom Ward, Iain Dillingham, Ben Goldacre, Miguel A Hernán, Jonathan A C Sterne
Publikováno v:
Horne, E M F, Hulme, W J, Keogh, R H, Palmer, T M, Williamson, E J, Parker, E PK, Green, A, Walker, V M, Walker, A J, Curtis, H J, Fisher, L, MacKenna, B, Croker, R, Hopcroft, L EM, Park, R Y, Massey, J, Morley, J, Mehrkar, A, Bacon, S, Evans, D, Inglesby, P, Morton, C E, Hickman, G, Davy, S, Ward, T, Dillingham, I, Goldacre, B, Hernán, M A & Sterne, J A C 2022, ' Waning effectiveness of BNT162b2 and ChAdOx1 covid-19 vaccines over six months since second dose : OpenSAFELY cohort study using linked electronic health records ', BMJ, vol. 378, e071249, pp. e071249 . https://doi.org/10.1136/bmj-2022-071249
ObjectiveTo estimate waning of covid-19 vaccine effectiveness over six months after second dose.DesignCohort study, approved by NHS England.SettingLinked primary care, hospital, and covid-19 records within the OpenSAFELY-TPP database.ParticipantsAdul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::007b75d62e6f5cb06fdfcf3a21f3818f
https://researchonline.lshtm.ac.uk/id/eprint/4667149/1/Horne_etal_2022_Waning-effectiveness-of-bnt162b2-and.pdf
https://researchonline.lshtm.ac.uk/id/eprint/4667149/1/Horne_etal_2022_Waning-effectiveness-of-bnt162b2-and.pdf
Autor:
Laurie A. Tomlinson, Chris Bates, Seb Bacon, Elizabeth A. Williamson, Amir Mehrkar, Krishnan Bhaskaran, Henry Drysdale, Richard Croker, Liam Smeeth, Angel Y S Wong, William J Hulme, Rosalind M Eggo, Jonathan Cockburn, Ben Goldacre, Stephen J. W. Evans, Caroline E Morton, Helen J Curtis, Peter Inglesby, Sam Harper, John Parry, Frank Hester, Anna Schultze, Helen Mcdonald, Christopher T Rentsch, Kevin Wing, Alex J Walker, Ian J. Douglas, Harriet Forbes, David M. Evans, Rohini Mathur, Brian MacKenna, Jeremy P Brown
Publikováno v:
Annals of the Rheumatic Diseases
Wong, AY, MacKenna, B, Morton, CE, Schultze, A, Walker, AJ, Bhaskaran, K, Brown, JP, Rentsch, CT, Williamson, E, Drysdale, H, Croker, R, Bacon, S, Hulme, W & Collaborative, OAFELY 2021, ' Use of non-steroidal anti-inflammatory drugs and risk of death from COVID-19 : an OpenSAFELY cohort analysis based on two cohorts ', Annals of the Rheumatic Diseases, vol. 80, no. 7, pp. 943-951 . https://doi.org/10.1136/annrheumdis-2020-219517
Wong, A Y S, MacKenna, B, Morton, C E, Schultze, A, Walker, A J, Bhaskaran, K, Brown, J P, Rentsch, C T, Williamson, E, Drysdale, H, Croker, R, Bacon, S, Hulme, W, Bates, C, Curtis, H J, Mehrkar, A, Evans, D, Inglesby, P, Cockburn, J, McDonald, H I, Tomlinson, L, Mathur, R, Wing, K, Forbes, H, Eggo, R M, Parry, J, Hester, F, Harper, S, Evans, S J W, Smeeth, L, Douglas, I J & Goldacre, B 2021, ' Use of non-steroidal anti-inflammatory drugs and risk of death from COVID-19 : An OpenSAFELY cohort analysis based on two cohorts ', Annals of the Rheumatic Diseases, vol. 80, no. 7, pp. 943-951 . https://doi.org/10.1136/annrheumdis-2020-219517
Wong, AY, MacKenna, B, Morton, CE, Schultze, A, Walker, AJ, Bhaskaran, K, Brown, JP, Rentsch, CT, Williamson, E, Drysdale, H, Croker, R, Bacon, S, Hulme, W & Collaborative, OAFELY 2021, ' Use of non-steroidal anti-inflammatory drugs and risk of death from COVID-19 : an OpenSAFELY cohort analysis based on two cohorts ', Annals of the Rheumatic Diseases, vol. 80, no. 7, pp. 943-951 . https://doi.org/10.1136/annrheumdis-2020-219517
Wong, A Y S, MacKenna, B, Morton, C E, Schultze, A, Walker, A J, Bhaskaran, K, Brown, J P, Rentsch, C T, Williamson, E, Drysdale, H, Croker, R, Bacon, S, Hulme, W, Bates, C, Curtis, H J, Mehrkar, A, Evans, D, Inglesby, P, Cockburn, J, McDonald, H I, Tomlinson, L, Mathur, R, Wing, K, Forbes, H, Eggo, R M, Parry, J, Hester, F, Harper, S, Evans, S J W, Smeeth, L, Douglas, I J & Goldacre, B 2021, ' Use of non-steroidal anti-inflammatory drugs and risk of death from COVID-19 : An OpenSAFELY cohort analysis based on two cohorts ', Annals of the Rheumatic Diseases, vol. 80, no. 7, pp. 943-951 . https://doi.org/10.1136/annrheumdis-2020-219517
Objectives To assess the association between routinely prescribed non-steroidal anti-inflammatory drugs (NSAIDs) and deaths from COVID-19 using OpenSAFELY, a secure analytical platform.Methods We conducted two cohort studies from 1 March to 14 June 2
Autor:
The OpenSAFELY Collaborative, Angel Y. S. Wong, Laurie A. Tomlinson, Jeremy P. Brown, William Elson, Alex J. Walker, Anna Schultze, Caroline E. Morton, David Evans, Peter Inglesby, Brian MacKenna, Krishnan Bhaskaran, Christopher T. Rentsch, Emma Powell, Elizabeth Williamson, Richard Croker, Seb Bacon, William Hulme, Chris Bates, Helen J. Curtis, Amir Mehrkar, Jonathan Cockburn, Helen I. McDonald, Rohini Mathur, Kevin Wing, Harriet Forbes, Rosalind M. Eggo, Stephen J. W. Evans, Liam Smeeth, Ben Goldacre, Ian J. Douglas
Publikováno v:
Journal of Hematology & Oncology
Wong, A Y S, Tomlinson, L A, Brown, J P, Elson, W, Walker, A J, Schultze, A, Morton, C E, Evans, D, Inglesby, P, MacKenna, B, Bhaskaran, K, Rentsch, C T, Powell, E, Williamson, E, Croker, R, Bacon, S, Hulme, W, Bates, C, Curtis, H J, Mehrkar, A, Cockburn, J, McDonald, H I, Mathur, R, Wing, K, Forbes, H, Eggo, R M, Evans, S J W, Smeeth, L & Goldacre, B & Douglas, I J 2021, ' Association between warfarin and COVID-19-related outcomes compared with direct oral anticoagulants : population-based cohort study ', Journal of Hematology and Oncology, vol. 14, no. 1, 172 . https://doi.org/10.1186/s13045-021-01185-0
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-10 (2021)
Wong, A Y S, Tomlinson, L A, Brown, J P, Elson, W, Walker, A J, Schultze, A, Morton, C E, Evans, D, Inglesby, P, MacKenna, B, Bhaskaran, K, Rentsch, C T, Powell, E, Williamson, E, Croker, R, Bacon, S, Hulme, W, Bates, C, Curtis, H J, Mehrkar, A, Cockburn, J, McDonald, H I, Mathur, R, Wing, K, Forbes, H, Eggo, R M, Evans, S J W, Smeeth, L & Goldacre, B & Douglas, I J 2021, ' Association between warfarin and COVID-19-related outcomes compared with direct oral anticoagulants : population-based cohort study ', Journal of Hematology and Oncology, vol. 14, no. 1, 172 . https://doi.org/10.1186/s13045-021-01185-0
Journal of Hematology & Oncology, Vol 14, Iss 1, Pp 1-10 (2021)
Background Thromboembolism has been reported as a consequence of severe COVID-19. Although warfarin is a commonly used anticoagulant, it acts by antagonising vitamin K, which is low in patients with severe COVID-19. To date, the clinical evidence on
Autor:
Bang Zheng, Amelia C A Green, John Tazare, Helen J Curtis, Louis Fisher, Linda Nab, Anna Schultze, Viyaasan Mahalingasivam, Edward P K Parker, William J Hulme, Sebastian C J Bacon, Nicholas J DeVito, Christopher Bates, David Evans, Peter Inglesby, Henry Drysdale, Simon Davy, Jonathan Cockburn, Caroline E Morton, George Hickman, Tom Ward, Rebecca M Smith, John Parry, Frank Hester, Sam Harper, Amir Mehrkar, Rosalind M Eggo, Alex J Walker, Stephen J W Evans, Ian J Douglas, Brian MacKenna, Ben Goldacre, Laurie A Tomlinson
Publikováno v:
BMJ. :e071932
Objective To compare the effectiveness of sotrovimab (a neutralising monoclonal antibody) with molnupiravir (an antiviral) in preventing severe outcomes of covid-19 in adult patients infected with SARS-CoV-2 in the community and at high risk of sever
Autor:
Amir Mehrkar, Nishi Chaturvedi, Rosalind M Eggo, William J Hulme, Helen Mcdonald, David G. Harrison, Nicholas J DeVito, Caroline E Morton, Jonathan Cockburn, Henry Drysdale, Rohini Mathur, Helen J Curtis, Stephen J. W. Evans, Peter Inglesby, Harriet Forbes, Angel Y S Wong, Richard Croker, Kamlesh Khunti, John Parry, Krishnan Bhaskaran, Liam Smeeth, Ian J. Douglas, Seb Bacon, Christopher M. Bates, Richard Grieve, David M. Evans, Brian MacKenna, Frank Hester, Christopher T Rentsch, Alex J Walker, Kevin Wing, Laurie A. Tomlinson, Elizabeth A. Williamson, Kathy Rowan, Ben Goldacre, Sam Harper, Anna Schultze
Publikováno v:
Mathur, R, Rentsch, C T, Morton, C E, Hulme, W J, Schultze, A, MacKenna, B, Eggo, R M, Bhaskaran, K, Wong, A Y S, Williamson, E J, Forbes, H, Wing, K, McDonald, H I, Bates, C, Bacon, S, Walker, A J, Evans, D, Inglesby, P, Mehrkar, A, Curtis, H J, DeVito, N J, Croker, R, Drysdale, H, Cockburn, J, Parry, J, Hester, F, Harper, S, Douglas, I J, Tomlinson, L, Evans, S J W, Grieve, R, Harrison, D, Rowan, K, Khunti, K, Chaturvedi, N & Smeeth, L & Goldacre, B 2021, ' Ethnic differences in SARS-CoV-2 infection and COVID-19-related hospitalisation, intensive care unit admission, and death in 17 million adults in England : an observational cohort study using the OpenSAFELY platform ', The Lancet, vol. 397, no. 10286, pp. 1711-1724 . https://doi.org/10.1016/S0140-6736(21)00634-6
MedRxiv
Lancet (London, England)
MedRxiv
Lancet (London, England)
BackgroundCOVID-19 has disproportionately affected minority ethnic populations in the UK. Our aim was to quantify ethnic differences in SARS-CoV-2 infection and COVID-19 outcomes during the first and second waves of the COVID-19 pandemic in England.M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0653ae8385d4322336b2631ea8b30340
https://www.pure.ed.ac.uk/ws/files/313286385/Ethnic_differences_in_SARS_CoV_2_infection_and_COVID_19_related_hospitalisation_intensive_care_unit_admission_and_death_in_17_million_adults_in_England.pdf
https://www.pure.ed.ac.uk/ws/files/313286385/Ethnic_differences_in_SARS_CoV_2_infection_and_COVID_19_related_hospitalisation_intensive_care_unit_admission_and_death_in_17_million_adults_in_England.pdf
Autor:
Henry Drysdale, Kevin Wing, Chris Bates, Frank Hester, Robert McManus, Amir Mehrkar, Brian MacKenna, Liam Smeeth, Ben Goldacre, Nicholas J DeVito, Christopher T Rentsch, Harriet Forbes, Alex J Walker, Rosalind M Eggo, William J Hulme, John Parry, David M. Evans, Stephen J. W. Evans, Jonathan Cockburn, Richard Croker, Helen J Curtis, Anna Schultze, Peter Inglesby, Angel Y S Wong, Krishnan Bhaskaran, Laurie A. Tomlinson, Seb Bacon, Helen Mcdonald, Elizabeth A. Williamson, Ian J. Douglas, Caroline E Morton, Caroline Minassian, Rohini Mathur, Sam Harper, Jeremy P Brown
Publikováno v:
Forbes, H, Morton, C E, Bacon, S, McDonald, H I, Minassian, C, Brown, J P, Rentsch, C T, Mathur, R, Schultze, A, Devito, N J, MacKenna, B, Hulme, W J, Croker, R, Walker, A J, Williamson, E J, Bates, C, Mehrkar, A, Curtis, H J, Evans, D, Wing, K, Inglesby, P, Drysdale, H, Wong, A Y S, Cockburn, J, McManus, R, Parry, J, Hester, F, Harper, S, Douglas, I J, Smeeth, L, Evans, S J W, Bhaskaran, K, Eggo, R M, Goldacre, B & Tomlinson, L A 2021, ' Association between living with children and outcomes from covid-19 : OpenSAFELY cohort study of 12 million adults in England ', The BMJ, vol. 372, n628 . https://doi.org/10.1136/bmj.n628
The BMJ
The BMJ
Objective To investigate whether risk of infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and outcomes of coronavirus disease 2019 (covid-19) differed between adults living with and without children during the first two wav
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af54e5a65536a5f5ffa012ad4870b9db
https://hdl.handle.net/20.500.11820/d939cf2c-1c48-4b7e-85de-e9c1954ad5ad
https://hdl.handle.net/20.500.11820/d939cf2c-1c48-4b7e-85de-e9c1954ad5ad
Autor:
Mary Ramsay, Laurie A. Tomlinson, Amir Mehrkar, Elizabeth A. Williamson, Dave Evans, Caroline Minassian, Rosalind M Eggo, Ben Goldacre, Chris Bates, Sam Harper, John Tazare, Stephen J. W. Evans, Simon Davy, Helen J Curtis, Peter Inglesby, Anna Schultze, Rohini Mathur, Frank Hester, Jonathan Cockburn, Brian MacKenna, Caroline E Morton, Christopher T Rentsch, Alex J Walker, Richard Croker, Liam Smeeth, Krishnan Bhaskaran, William J Hulme, Angel Y S Wong, Hannah Kuper, Ian J. Douglas, Kevin Wing, Harriet Forbes, Sebastian Bacon, Helen Mcdonald, John Parry, Emily Nightingale
Publikováno v:
The BMJ
Williamson, E J, McDonald, H I, Bhaskaran, K, Walker, A J, Bacon, S, Davy, S, Schultze, A, Tomlinson, L, Bates, C, Ramsay, M, Curtis, H J, Forbes, H, Wing, K, Minassian, C, Tazare, J, Morton, C E, Nightingale, E, Mehrkar, A, Evans, D, Inglesby, P, MacKenna, B, Cockburn, J, Rentsch, C T, Mathur, R, Wong, A Y S, Eggo, R M, Hulme, W, Croker, R, Parry, J, Hester, F, Harper, S, Douglas, I J, Evans, S J W, Smeeth, L, Goldacre, B & Kuper, H 2021, ' Risks of covid-19 hospital admission and death for people with learning disability : Population based cohort study using the OpenSAFELY platform ', The BMJ, vol. 374, n1592 . https://doi.org/10.1136/bmj.n1592
Williamson, E J, McDonald, H I, Bhaskaran, K, Walker, A J, Bacon, S, Davy, S, Schultze, A, Tomlinson, L, Bates, C, Ramsay, M, Curtis, H J, Forbes, H, Wing, K, Minassian, C, Tazare, J, Morton, C E, Nightingale, E, Mehrkar, A, Evans, D, Inglesby, P, MacKenna, B, Cockburn, J, Rentsch, C T, Mathur, R, Wong, A Y S, Eggo, R M, Hulme, W, Croker, R, Parry, J, Hester, F, Harper, S, Douglas, I J, Evans, S J W, Smeeth, L, Goldacre, B & Kuper, H 2021, ' Risks of covid-19 hospital admission and death for people with learning disability : Population based cohort study using the OpenSAFELY platform ', The BMJ, vol. 374, n1592 . https://doi.org/10.1136/bmj.n1592
Objective To assess the association between learning disability and risk of hospital admission and death from covid-19 in England among adults and children. Design Population based cohort study on behalf of NHS England using the OpenSAFELY platform.
Autor:
Paul Little, Clare Bankhead, Carl Heneghan, FD Richard Hobbs, Ben Goldacre, Jeffrey K Aronson, Chris Salisbury, Rafael Perera, Sarah Stevens, Jack W. O’Sullivan
Publikováno v:
O'Sullivan, J W, Stevens, S, Hobbs, F D R, Salisbury, C, Little, P, Goldacre, B, Bankhead, C, Aronson, J K, Perera, R & Heneghan, C 2018, ' Temporal trends in use of tests in UK primary care, 2000-15 : retrospective analysis of 250 million tests ', BMJ, vol. 363, k4666 . https://doi.org/10.1136/bmj.k4666
The BMJ
The BMJ
Objectives To assess the temporal change in test use in UK primary care and to identify tests with the greatest increase in use. Design Retrospective cohort study. Setting UK primary care. Participants All patients registered to UK General Practices