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Autor:
Daniel Moj, Nicola Ammer, Babette Aicher, Jan-Georg Wojtyniak, Thorsten Lehr, Michael Teifel, Herbert Sindermann, Hannah Britz, Nina Hanke
Zoptarelin doxorubicin is a fusion molecule of the chemotherapeutic doxorubicin and a luteinizing hormone-releasing hormone receptor (LHRHR) agonist, designed for drug targeting to LHRHR positive tumors. The aim of this study was to establish a physi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28c5e9a18956370d7aca5ee1061fd910
Publikováno v:
Alcohol. 98:19-24
This research investigated variations in alcohol consumption by socioeconomic factors and hypertensive status in South Korean adults, aged ≥19 years. This is a secondary data analysis using the Korea National Health and Nutrition Examination Survey
Autor:
Junaid Khan, Rufi Shaikh
Publikováno v:
Alcohol. 97:23-30
Purpose of the study: Alcohol use is the third leading risk factor for premature mortality. India is one of the largest markets for alcoholic beverages. Existing research in India is localized to specific settings lacking national generalizability. T
Autor:
Maria Ospina, Bruce P. Lanphear, Kimberly Yolton, Zana Percy, Yingying Xu, Antonia M. Calafat, Kim N. Dietrich, Kim M. Cecil, Joseph M. Braun, Aimin Chen, Ann M. Vuong, Changchun Xie
Publikováno v:
Neurotoxicology
Many environmental chemicals are being identified as suspected neurotoxicants based on the findings of both experimental and epidemiological studies. Organophosphate esters (OPEs), which are among the chemicals that have replaced neurotoxic polybromi
Publikováno v:
Human & Experimental Toxicology. 40:S583-S592
Introduction The present study was undertaken to investigate the prognostic value of the frontal QRS-T angle associated with adverse cardiac outcomes in patients with carbon monoxide (CO) poisoning in early stages in the emergency department. Materia
Autor:
Nancy Chan, Jiuping Ji, Antoinette R. Tan, Janice M. Mehnert, Alice P. Chen, Jan H. Beumer, Mansi Shah, Joseph Aisner, Murugesan Gounder, Jyoti Malhotra, Rebecca A. Moss, Yong Lin, Brian F. Kiesel, Hongxia Lin, Mark N. Stein, Michael P. Kane
Publikováno v:
Cancer Chemother Pharmacol
Purpose Veliparib (V), an oral poly(ADP-ribose) polymerase (PARP) inhibitor, potentiates effects of alkylating agents and topoisomerase inhibitors in preclinical tumor models. We conducted a phase I trial of V with iv cyclophosphamide (C) and V plus
Autor:
Raphael Teipel, Susanne Quick, Stephan Richter, Holger Knoth, Theresa Kretschmann, Frank Kroschinsky, Christoph Röllig, Ekaterina Balaian, Nael Alakel, Martin Bornhäuser, Sandra Heuschkel, Malte von Bonin, Simone von Bonin
Publikováno v:
Cancer Chemotherapy and Pharmacology
Purpose High-dose methotrexate (HDMTX)-associated acute kidney injury with delayed MTX clearance has been linked to an excess in MTX-induced toxicities. Glucarpidase is a recombinant enzyme that rapidly hydrolyzes MTX into non-toxic metabolites. The
Autor:
John I. Anetor, Opeyemi A Adetunji, Nnodimele O. S. Atulomah, Osahon S Usiobeigbe, Nnenna L. Nwobi, Joseph C. Nwobi, Esther Ngozi Adejumo
Publikováno v:
Toxicology and Industrial Health. 37:705-713
Lead is an occupational toxicant and a recognised health threat particularly in developing countries. Hence, this study explored the interaction of blood lead level (BLL), a conventional marker of lead exposure, with indices of calcium metabolism and
Autor:
Marc A. Schuckit, Tom L. Smith
Publikováno v:
Alcoholism, clinical and experimental research, vol 45, iss 10
Background Diagnostic and Statistical Manual (DSM) alcohol use disorder (AUD) criteria are written in broad enough terms to apply to diverse populations. The current analyses evaluate whether the endorsement of criteria changes with increasing age in
Autor:
Guang Jia, Tiancheng Wang, Changmao Long, Pai Zheng, Shanfa Yu, Fangda Peng, Chunguang Ding, Tian Chen, Guiping Hu, Zekang Su, Yali Zhang
Publikováno v:
Toxicology Letters. 349:92-100
Hexavalent chromium (Cr(VI)) compound is considered as a common environmental and occupational pollutant due to widespread application in industry and agriculture. Cr(VI) as a carcinogen poses a serious threat to human health and the underlying mecha