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Autor:
Qing Cao, Najla El Jurdi, Daniel J. Weisdorf, Veronika Bachanova, Joseph Maakaron, Mukta Arora, Brian C. Betts, Erica D. Warlick, Shernan G. Holtan, Claudio G. Brunstein, Timothy D. Gauntner, Fiona He
Publikováno v:
Transplantation and Cellular Therapy. 28:88-95
Background : Higher CD34 cell dose is associated with improved engraftment after peripheral blood allogeneic hematopoietic stem cell transplantation (alloHCT), but may also increase the risk of long-term complications, such as graft-versus-host disea
Autor:
Shoji Koga, Yutaka Horiguchi
Publikováno v:
Journal of Cellular and Molecular Medicine
Majority of current treatment strategies against erectile dysfunction (ED) has been consisted of only a supportive care to sustain enough erection during a sexual intercourse. In this study, we investigated whether the cultured conditioned medium of
Autor:
Chenfang Wu, Fang Wu, Siye Zhang, Yanjun Zhong, Chao Wu, Guobao Wu, Bo Yu, Shangjie Wu, Guyi Wang, Quan Zhang
Publikováno v:
Journal of Cellular and Molecular Medicine
This study aims to evaluate the effect of non‐alcoholic fatty liver disease (NAFLD) on the susceptibility and consequences of coronavirus disease 2019 (COVID‐19). We retrospectively collected data from 218 adult COVID‐19 patients who showed no
Autor:
Steen Buntzen, Moustapha Kassem, Michaela Tencerova, Helene Tarri Hougaard, Bodil Ginnerup Pedersen, Lilli Lundby, Stig Norderval
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-12 (2021)
Tencerova, M, Lundby, L, Buntzen, S, Norderval, S, Hougaard, H T, Pedersen, B G & Kassem, M 2021, ' Molecular differences of adipose-derived mesenchymal stem cells between non-responders and responders in treatment of transphincteric perianal fistulas ', Stem Cell Research & Therapy, vol. 12, 586 . https://doi.org/10.1186/s13287-021-02644-8
Tencerova, M, Lundby, L, Buntzen, S, Norderval, S, Hougaard, H T, Pedersen, B G & Kassem, M 2021, ' Molecular differences of adipose-derived mesenchymal stem cells between non-responders and responders in treatment of transphincteric perianal fistulas ', Stem Cell Research and Therapy, vol. 12, 586 . https://doi.org/10.1186/s13287-021-02644-8
Stem Cell Research & Therapy
Tencerova, M, Lundby, L, Buntzen, S, Norderval, S, Hougaard, H T, Pedersen, B G & Kassem, M 2021, ' Molecular differences of adipose-derived mesenchymal stem cells between non-responders and responders in treatment of transphincteric perianal fistulas ', Stem Cell Research & Therapy, vol. 12, 586 . https://doi.org/10.1186/s13287-021-02644-8
Tencerova, M, Lundby, L, Buntzen, S, Norderval, S, Hougaard, H T, Pedersen, B G & Kassem, M 2021, ' Molecular differences of adipose-derived mesenchymal stem cells between non-responders and responders in treatment of transphincteric perianal fistulas ', Stem Cell Research and Therapy, vol. 12, 586 . https://doi.org/10.1186/s13287-021-02644-8
Stem Cell Research & Therapy
Background Injection of autologous adipose tissue (AT) has recently been demonstrated to be an effective and safe treatment for anal fistulas. AT mesenchymal stem cells (AT-MSCs) mediate the healing process, but the relationship between molecular cha
Autor:
Maryam Salimi, Mohammad Mahdi Majidi, Elham Roshandel, Sarvenaz Samadi Kochaksaraei, Abbas Hajifathali, Farshid Alaeddini, Sepide Kazemi, Nasser Aghdami, Behnam Sadeghi, Olle Ringdén, Ali Pirsalehi, Hoda Sadrosadat, Ghazaleh Sankanian
Publikováno v:
Journal of Cellular and Molecular Medicine
Acute respiratory distress syndrome (ARDS) is the most common cause of death in COVID‐19 patients. The cytokine storm is the main driver of the severity and magnitude of ARDS. Placenta‐derived decidua stromal cells (DSCs) have a stronger immunosu
Autor:
Seongho Kim, Abhinav Deol, Dipenkumar Modi, Lois Ayash, Joseph P. Uberti, Voravit Ratanatharathorn, Kyle Kondrat
Publikováno v:
Transplantation and Cellular Therapy. 27:760-767
Limited information is available on the efficacy of post-transplantation cyclophosphamide (PTcy) or thymoglobulin for graft-versus-host disease (GVHD) prophylaxis in mismatched unrelated donor (MMUD) transplants. We retrospectively compared outcomes
Autor:
Sofie Vinther Skriver, Tahmina Khawajazada, Nicoline Løkken, John Vissing, Jesper Helbo Storgaard
Publikováno v:
Løkken, N, Skriver, S V, Khawajazada, T, Storgaard, J H & Vissing, J 2021, ' Plasma lactate responses during and after submaximal handgrip exercise are not diagnostically helpful in mitochondrial myopathy ', Mitochondrion, vol. 60, pp. 21-26 . https://doi.org/10.1016/j.mito.2021.07.002
Introduction/background Mitochondrial myopathy (MM) encompasses a clinical heterogenous group of patients that can be difficult to diagnose. The aim of this study was to investigate if changes in plasma lactate concentration during a 6-minute submaxi
Autor:
Xinghe Wang, Lu Qi, Chen Liu, Jincan Liu, Haihong Bai, Yu Wang, Chengquan Han, Pu Li, Chunpu Lei, Long Liu, Yinjian Sun
Publikováno v:
Journal of Cellular and Molecular Medicine
The study evaluated the safety, tolerability, pharmacokinetics (PK) and anti‐drug antibody (ADA) of the recombinant human thymosin β4 (NL005) for single and multiple intravenous injections in healthy subjects. Seven cohorts, with 54 healthy subjec
Autor:
Yasushi Onishi, Takanori Ohta, Makoto Onizuka, Naoyuki Uchida, Nobuaki Nakano, Takeshi Kobayashi, Yoshinobu Kanda, Yoshiko Atsuta, Jun Aoki, Shuichi Ota, Hikaru Kobayashi, Yukiyasu Ozawa, Takahiro Fukuda, Yuta Katayama, Takaaki Konuma
Publikováno v:
Transplantation and Cellular Therapy. 27:671-678
Background : Most patients of myelodysplastic syndrome (MDS) require red blood cell (RBC) and/or platelet transfusion during their disease courses, which could cause an increased risk of iron overload and alloimmunization. However, it remains less cl
Autor:
Xiangyang Zhu, Megan M. Ostlie, Kyra L. Jordan, Sabena M. Conley, Nattawat Klomjit, Lilach O. Lerman, Amir Lerman
Publikováno v:
Journal of Cellular and Molecular Medicine
Immune‐modulatory properties of adipose tissue‐derived mesenchymal stem/stromal cells (MSCs) might be susceptible to metabolic disturbances. We hypothesized that the immune‐modulatory function of MSCs might be blunted in obese human subjects. M