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Publikováno v:
Cochrane Database Syst Rev
The Cochrane Library
The Cochrane Library
Inhaled antibiotics are commonly used to treat persistent airway infection with Pseudomonas aeruginosa that contributes to lung damage in people with cystic fibrosis. Current guidelines recommend inhaled tobramycin for individuals with cystic fibrosi
Publikováno v:
BMJ case reports. 14(8)
Nitrous oxide (NO) is an inhalant that has become increasingly popular as a recreational drug. While it is presumed to be harmless, a number of adverse effects of NO have been described. We discuss the case of a 24-year-old man with no medical histor
Autor:
Chiara Finocchiaro, Simona Toscano, Salvatore Lo Fermo, Francesco Patti, Enrico Millefiorini, Eleonora Sgarlata, Clara Grazia Chisari
Publikováno v:
Current Neuropharmacology. 20:1978-1987
Background: Progressive Multifocal Leukoencephalopathy (PML) is an opportunistic infection caused by John Cunningham virus (JCV) reactivation, potentially associated with natalizumab (NTZ) treatment for Multiple Sclerosis (MS). The anti-JCV antibodie
Autor:
Lesley A. Inker, Hiddo J.L. Heerspink, Tord Rikte, Shira Perl, Sapphire investigators, Tom Greene, Vlado Perkovic, Magnus K. Bjursell, Fredrik Erlandsson, Robert Terkeltaub, Austin G. Stack
Publikováno v:
Nephrology Dialysis Transplantation, 37(8), 1461-1471. Oxford University Press
Background Verinurad is a human uric acid (UA) transporter (URAT1) inhibitor known to decrease serum UA (sUA) levels and that may reduce albuminuria. In a Phase 2a study (NCT03118739), treatment with verinurad + febuxostat lowered urine albumin-to-cr
Autor:
Michelle G. Pedler, Jeffrey L. Olson, Joshua L. Morgenstern, Anthony A. Jones, Divneet Mandair
Publikováno v:
RETINAL Cases & Brief Reports. 16:515-519
To present a case of idiopathic retinal vasculitis, aneurysms, and neuroretinitis syndrome that was successfully managed with serial intravitreal aflibercept injections.Ophthalmic imaging and visual acuity were used to monitor disease state and track
Publikováno v:
Exp Clin Psychopharmacol
Experimental and clinical psychopharmacology, vol 30, iss 3
Experimental and clinical psychopharmacology, vol 30, iss 3
Research on nicotine metabolism has primarily focused on white adults. This study examined associations between nicotine metabolism, tobacco use, and demographic characteristics among Alaska Native adults who smoke cigarettes. Participants (N = 244)
Autor:
Martijn Gerritsen, Marek Rajzer, Giovambattista Desideri, Cristina Giannattasio, Anne-Kathrin Tausche, Claudio Borghi, Michael T. Nurmohamed
Publikováno v:
European Heart Journal-Cardiovascular Pharmacotherapy, 8(3), 236-242. Oxford University Press
Desideri, G, Rajzer, M, Gerritsen, M, Nurmohamed, M T, Giannattasio, C, Tausche, A-K & Borghi, C 2022, ' Effects of intensive urate lowering therapy with febuxostat in comparison with allopurinol on pulse wave velocity in patients with gout and increased cardiovascular risk : the FORWARD study ', European heart journal. Cardiovascular pharmacotherapy, vol. 8, no. 3, pp. 236-242 . https://doi.org/10.1093/ehjcvp/pvaa144
European heart journal. Cardiovascular pharmacotherapy, 8(3), 236-242. Oxford University Press
Desideri, G, Rajzer, M, Gerritsen, M, Nurmohamed, M T, Giannattasio, C, Tausche, A-K & Borghi, C 2022, ' Effects of intensive urate lowering therapy with febuxostat in comparison with allopurinol on pulse wave velocity in patients with gout and increased cardiovascular risk : the FORWARD study ', European heart journal. Cardiovascular pharmacotherapy, vol. 8, no. 3, pp. 236-242 . https://doi.org/10.1093/ehjcvp/pvaa144
European heart journal. Cardiovascular pharmacotherapy, 8(3), 236-242. Oxford University Press
Aims Hyperuricaemia and gout are strongly related with traditional cardiovascular risk factors and vascular damage. This study aimed to assess whether febuxostat and allopurinol could differently influence carotid-femoral pulse wave velocity (cfPWV)
Publikováno v:
BMJ Case Rep
A previously healthy postpartum 33-year-old woman was admitted at the emergency department after two episodes of syncope. In the waiting room, she collapsed, ventricular fibrillation was detected, and she was reanimated by electric cardioversion. At
Autor:
Keijiro Sato, Hidetoshi Satomi, Toshimitsu Ueki, Hikaru Kobayashi, Mayumi Ueno, Yuki Hiroshima, Naoaki Ichikawa, Masahiko Sumi
Publikováno v:
Internal Medicine. 61:1225-1230
Two adult patients with acute leukemia developed transplantation-associated microangiopathy (TAM) related to graft-versus-host disease (GVHD). Both patients were resistant to standard therapy for TAM and GVHD, which led to markedly elevated serum tot
Autor:
Rajendra P. Singh, Kimberly K. Adkison, Mark Baker, Ridhi Parasrampuria, Allen Wolstenholme, Mark Davies, Nicola Sewell, Cindy Brothers, Ann M. Buchanan
Publikováno v:
Pediatric Infectious Disease Journal. 41:230-237
BACKGROUND The World Health Organization (WHO) 2019 antiretroviral treatment guidelines recommend use of optimal treatment regimens in all populations. Dolutegravir-based regimens are the preferred first-line and second-line treatment in infants and