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Autor:
Ulrich Gatzemeier, Michael Boyer, Paolo Paoletti, Salih Emri, Christian Manegold, Claude Denham, Nicholas J. Vogelzang, James J. Rusthoven, James T. Symanowski, Clet Niyikiza, E. Kaukel, Pierre Ruffié
Publikováno v:
Journal of Clinical Oncology. 41:2125-2133
PURPOSE Patients with malignant pleural mesothelioma, a rapidly progressing malignancy with a median survival time of 6 to 9 months, have previously responded poorly to chemotherapy. We conducted a phase III trial to determine whether treatment with
Autor:
Lajos Pusztai, Gabriel N. Hortobagyi, Bryan T. Hennessy, Massimo Cristofanilli, Chafika Mazouni, Fabrice Andre, Attila Tordai, W. Fraser Symmans, Cornelia Liedtke, Marjorie C. Green, Ana M. Gonzalez-Angulo, Kenneth R. Hess, Jaime A. Mejia
Publikováno v:
Journal of Clinical Oncology. 41:1809-1815
PURPOSE Triple-negative breast cancer (TNBC) is defined by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER-2) expression. In this study, we compared response to neoadjuvant chemotherap
Publikováno v:
Journal of Clinical Oncology. 41:1331-1338
PURPOSE Immunohistochemistry (IHC) is a newer technique for assessing the estrogen receptor (ER) status of breast cancers, with the potential to overcome many of the shortcomings associated with the traditional ligand-binding assay (LBA). The purpose
Autor:
Adriana Garduño-Alanis, Lizbeth Morales-González, Angélica Ángeles-Llerenas, José Zaim Delgado-Ramírez, Carolina Ortega-Olvera, Gabriela Torres-Mejía
Publikováno v:
Cancer Causes & Control. 33:1355-1361
The delay in the time (in calendar days) from the delivery of mammography results to histopathological breast cancer (BC) diagnosis could be associated with more advanced clinical stages, a worse prognosis and higher mortality. Therefore, we assessed
Autor:
Christian Lang, Felix Egger, Mir Alireza Hoda, Alessandro Saeed Querner, Bence Ferencz, Victor Lungu, Robert Szegedi, Levente Bogyo, Klara Torok, Felicitas Oberndorfer, Thomas Klikovits, Anna Schwendenwein, Kristiina Boettiger, Ferenc Renyi-Vamos, Konrad Hoetzenecker, Karin Schelch, Zsolt Megyesfalvi, Balazs Dome
Publikováno v:
Lung Cancer. 169:40-46
The prognostic value of lymphocyte-to-monocyte ratio (LMR) has already been evaluated in a wide range of malignancies including patients with non-surgically managed small cell lung cancer (SCLC). However, the impact of LMR on survival in surgically t
Autor:
David M. O'Malley, Maryna Neffa, Bradley J. Monk, Tamar Melkadze, Marilyn Huang, Anna Kryzhanivska, Iurie Bulat, Tarek M. Meniawy, Andrea Bagameri, Edward W. Wang, Bernard Doger de Speville Uribe, Roberto Hegg, Waldo Ortuzar Feliu, Marek Ancukiewicz, Iwona Lugowska
Publikováno v:
Journal of clinical oncology : official journal of the American Society of Clinical Oncology. 40(7)
PURPOSE Balstilimab (antiprogrammed death-1) and zalifrelimab (anticytotoxic T-lymphocyte–associated antigen-4) are two new checkpoint inhibitors emerging as promising investigational agents for the treatment of advanced cervical cancer. This phase
Autor:
Jana Käthe Striefler, Maren Schmiester, Franziska Brandes, Anne Dörr, Stefan Pahl, David Kaul, Daniel Rau, Eva‐Maria Dobrindt, Georgios Koulaxouzidis, Lars Bullinger, Sven Märdian, Anne Flörcken
Publikováno v:
Cancer Medicine. 11:3213-3225
BACKGROUND: Ewing family of tumors (EFT) is rarely diagnosed in patients (pts) over the age of 18 years (years), and data on the clinical course and the outcome of adult EFT pts is sparse. METHODS: In this retrospective analysis, we summarize our exp
Autor:
Zhouwei Zhan, Xiaojie Wang, Jiami Yu, Jingxian Zheng, Yi Zeng, Mingyao Sun, Li Peng, Zengqing Guo, Bijuan Chen
Publikováno v:
Future Oncology. 18:1259-1271
Objective: To investigate the efficacy and safety of intraperitoneal administration of recombinant human endostatin in gastric cancer with malignant ascites. Methods: Clinical data of 90 patients (37 in an Endostar® combined with cisplatin group and
Publikováno v:
Anticancer Research. 42:1301-1306
Background/aim: Functional and bioinformatic studies provide strong evidence that long non-coding RNAs (lncRNAs) can alter the molecular mechanisms of cancer through their interactions with DNA, RNAs, and proteins. This study aimed to evaluate the ro
Autor:
Shuai Liu, Ruikun Li, Qiufang Liu, Dazheng Sun, Hongxing Yang, Herong Pan, Lisheng Wang, Shaoli Song
Publikováno v:
Cancer Biomarkers. 33:249-259
BACKGROUND: To explore an effective predictive model based on PET/CT radiomics for the prognosis of early-stage uterine cervical squamous cancer. METHODS: Preoperative PET/CT data were collected from 201 uterine cervical squamous cancer patients with