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Publikováno v:
Clinical Breast Cancer. 22:170-177
Background Accurate assessment of the axillary lymph nodes (aLNs) in breast cancer patients is essential for prognosis and treatment planning. Current radiological staging of nodal metastasis has poor accuracy. This study aimed to investigate the mac
Autor:
Shingo Yamamoto, Yusuke Yamada, Yoshie Yoshikawa, Akihiro Kanematsu, Mitsuru Emi, Yukako Nakanishi-Shinkai, Karel de Groot, Tomoko Hashimoto-Tamaoki, Jan Smout, Suvi Savola, Michio Nojima, Lilit Atanesyan, Masaki Ohmuraya
Publikováno v:
Cancer Science
Precise quantification of copy‐number alterations (CNAs) in a tumor genome is difficult. We have applied a comprehensive copy‐number analysis method, digital multiplex ligation‐dependent probe amplification (digitalMLPA), for targeted gene copy
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-13 (2021)
BMC Cancer
BMC Cancer
Background Lymph node metastasis (LNM) status is an important prognostic factor that strongly influences the treatment decision of early gastric cancer (EGC). This study aimed to evaluate the pattern and clinical significance of LNM in EGC. Methods A
Autor:
Minhua Zheng, Yiming Miao, Zhuoqing Xu, Yaping Zong, Wenqing Feng, Yuchen Zhang, Zifeng Xu, Ai-Guo Lu, Jingkun Zhao, Wenchang Li, Han Gao
Publikováno v:
International Journal of Cancer. 150:509-520
Platelets promote tumor growth and metastasis in several tumor types. Recent research has found platelets can extravasate and infiltrate into the tumor stroma and interact with the tumor microenvironment. The prognostic role of platelet infiltration
Autor:
Atanas Ignatov, Piotr Czapiewski, Thomas Kalinski, Willi Pieper, Norbert Nass, Johannes Haybaeck
Publikováno v:
Cancer Biomarkers. 32:161-173
BACKGROUND: Neuronatin (NNAT) determined by immunohistochemistry is a negative prognostic biomarker for breast cancer, independent of the major clinicopathological markers. OBJECTIVE: Here, we investigated whether NNAT is also a predictive biomarker
Autor:
Arjun Sahgal, Umberto Ricardi, Hanbo Chen, Matthew Foote, Tithi Biswas, Kristin J. Redmond, Roi Dagan, Xuguang Chen, Darby Erler, Alexander V. Louie, Serena Badellino, Ian Poon
Publikováno v:
Cancer Medicine, Vol 10, Iss 18, Pp 6189-6198 (2021)
Cancer Medicine
Cancer Medicine
Background Stereotactic body radiotherapy (SBRT) is increasingly used to treat oligometastatic disease (OMD), but the effect of metastasis timing on patient outcomes remains uncertain. Methods An international database of patients with OMD treated wi
Autor:
Tetsuya Ikemoto, Shinichiro Yamada, Yu Saito, Mitsuo Shimada, Yuji Morine, Kazunori Tokuda, Masaaki Nishi, Katsuki Miyazaki
Publikováno v:
Anticancer Research. 41:4637-4644
Background/aim The aim of this study was to investigate frailty as a prognostic factor in patients with colorectal liver metastasis undergoing hepatectomy. Patients and methods Eighty-seven patients who underwent hepatectomy at our institution were e
Autor:
Xiaoxuan Sun, Yaojun Peng, Juan Yang, Qiyan Wu, Dong Zhang, Huan Wang, Qi Chen, Jing Zhao, Gaowa Sharen, Fan Yin
Publikováno v:
FEBS Open Bio, Vol 11, Iss 9, Pp 2490-2506 (2021)
FEBS Open Bio
FEBS Open Bio
The accumulation of various genetic and epigenetic changes in colonic epithelial cells has been identified as one of the fundamental processes that drive the initiation and progression of colorectal cancer (CRC). This study aimed to explore functiona
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-10 (2021)
BMC Cancer
BMC Cancer
Objective The main aim of this study was to ascertain the effectiveness of ultrasound-guided fine needle aspiration cytology (US-FNAC) in the diagnosis of para-aortic lymph node (PALN) metastasis in uterine cervical cancer and to establish its potent
Publikováno v:
Cancer Medicine, Vol 10, Iss 16, Pp 5545-5556 (2021)
Cancer Medicine
Cancer Medicine
Epigenetic regulation is important for cancer tumor metastasis and progression, including lung and liver cancer. However, the mechanism of epigenetic regulation in liver cancer leaves much to be discussed. According to a previous study, p300/CBP‐as