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Autor:
Lajos Pusztai, Gabriel N. Hortobagyi, Bryan T. Hennessy, Massimo Cristofanilli, Chafika Mazouni, Fabrice Andre, Attila Tordai, W. Fraser Symmans, Cornelia Liedtke, Marjorie C. Green, Ana M. Gonzalez-Angulo, Kenneth R. Hess, Jaime A. Mejia
Publikováno v:
Journal of Clinical Oncology. 41:1809-1815
PURPOSE Triple-negative breast cancer (TNBC) is defined by the lack of estrogen receptor (ER), progesterone receptor (PR), and human epidermal growth factor receptor 2 (HER-2) expression. In this study, we compared response to neoadjuvant chemotherap
A Systematic Comparison of Overall Survival Between Men and Women With Triple Negative Breast Cancer
Autor:
Mohammad Muhsin Chisti, Swechchha Silwal, Geetha Krishnamoorthy, Siddhartha Yadav, Sumeet Kumar Yadav
Publikováno v:
Clinical Breast Cancer. 22:161-169
Introduction Triple-negative breast cancer (TNBC) in men is very rare. The clinical characteristics, prognostic factors, and overall survival of men with TNBC have not been characterized. Methods The study population consisted of men and women with a
Publikováno v:
BMC Cancer, Vol 22, Iss 1, Pp 1-9 (2022)
BMC Cancer
BMC Cancer
Background It is estimated that breast cancer (BC) incidence, especially that of early-stage breast cancer cases continues to rise due to increased universal screening. Breast-conserving surgery (BCS) is the main intervention for early-stage BC. Lymp
Autor:
Henriette Christgen, Laura Bollmann, Mieke Raap, Rachel Wuerstlein, Bahriye Aktas, Ronald E. Kates, Ulrike Nitz, Ulrich Lehmann, Monika Graeser, Oleg Gluz, Michael Braun, Hans Kreipe, Sherko Kuemmel, Claudia Schumacher, Matthias Christgen, Malte Gronewold, Stephan Bartels, Nadia Harbeck, Eva-Maria Grischke, Christine Eulenburg, Isabel Grote, Kerstin Luedtke-Heckenkamp, Leonie Kandt
Publikováno v:
Cancer Medicine, Vol 10, Iss 23, Pp 8581-8594 (2021)
Cancer Medicine
Cancer Medicine
Background Whereas the genomic landscape of endocrine‐resistant breast cancer has been intensely characterized in previously treated cases with local or distant recurrence, comparably little is known about genomic alterations conveying primary non
Autor:
Linu Abraham Jacob, M C Suresh Babu, Smitha Saldanha, L K Rajeev, A H Rudresha, K N Lokesh, Usha Amirtham, A. Thottian, D. Lokanatha, Shina Goyal
Publikováno v:
Breast Disease. 41:115-121
BACKGROUND: The present era of individualized treatment for breast cancer is influenced by the initial disease status including the anatomical extent, grade, and receptor status. An accurate preoperative staging is the basis of treatment planning and
Publikováno v:
Molecular Biology Reports. 49:531-537
Signal recognition particle (SRP) promotes co-translational translocation of the proteins through or into the endoplasmic reticulum membrane and it also has elongation arrest function. SRP9 is one of the six protein subunits of SRP and functions in e
Publikováno v:
Int J Cancer
High nut consumption is associated with reduced total and certain cause-specific mortality in general populations. However, its association with cancer outcomes among long-term breast cancer survivors remains unknown. We examined the associations of
Autor:
Christoph Röcken, HM Behrens, F. W. Schäfer, L.-J. Kramp, M. van Mackelenbergh, Micaela Mathiak
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Background We explored the hypothesis that high-quality standards in diagnostic mammography can lead to an early diagnosis of breast cancers and identifies at risk populations outside screening programs. The histopathological features and distributio
Publikováno v:
Clinical Breast Cancer. 21:e611-e617
Purpose : The breast-conserving surgery (BCS) rate of breast cancer patients in China is much lower than that in Europe and the United States. This study aims to identify factors affecting the choice of surgical modality following neoadjuvant chemoth
Publikováno v:
FEBS Open Bio, Vol 11, Iss 9, Pp 2586-2599 (2021)
FEBS Open Bio
FEBS Open Bio
Butyrophilin 3A1 (BTN3A1), a major histocompatibility complex‐associated gene that encodes a membrane protein with two extracellular immunoglobulin domains and an intracellular B30.2 domain, is critical in T‐cell activation and adaptive immune re