Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Tarja Laitinen"'
Autor:
Erik Melén, Göran Pershagen, Sara Bruce, Josef Riedler, Cecilia M. Lindgren, Fredrik Nyberg, Gert Doekes, Roger Lauener, Marianne van Hage-Hamsten, Michael Kabesch, Annika Scheynius, Juha Kere, Magnus Wickman, Tarja Laitinen
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 171:1089-1095
Allergic diseases are influenced by both genes and environment. A 70-kb haplotype block in the G protein-coupled receptor for asthma susceptibility gene (GPR154; alias GPRA) on chromosome 7p was recently identified to influence susceptibility to asth
Autor:
Siri Lehtonen, P Koistinen, Juha Kere, Tarja Laitinen, Sakari Kakko, Vesa Ollikainen, Markku J. Savolainen, V L Kinnula
Publikováno v:
Europe PubMed Central
University of Helsinki
University of Helsinki
Background: Functional polymorphisms in the genes encoding superoxide dismutases (SOD)—that is, superoxide scavenging antioxidant enzymes—may play an important role in the development of inflammatory airway diseases such as asthma. Methods: The a
Autor:
Jaakko Kaprio, Torsten Winter, Markku Koskenvuo, Tarja Laitinen, Lauri A. Laitinen, Maija Räsänen
Publikováno v:
Twin Research. 4:392-399
Previous studies have suggested that perinatal factors influence the risk for asthma but population studies on perinatal factors and risk for hay fever are few. We studied the effect of perinatal factors on the risk for hay fever among adolescent twi
Autor:
Tarja Laitinen, Kathleen C. Barnes, Hong Chen, Matthias Wjst, Paul Burton, William O.C.M. Cookson, John W. Holloway, Robert C. Elston, Lyle J. Palmer, Klaus A. Deichmann, Kevin B. Jacobs
Publikováno v:
Hum. Mol. Genet. 10, 891-899 (2001)
Asthma is a common, complex human disease. Gene discovery in asthma has been complicated by substantial etiological heterogeneity, the possibility of genes of small effect and the concomitant requirement for large sample sizes. Linkage to asthma phen
Real-world clinical data identifies gender-related profiles in chronic obstructive pulmonary disease
Autor:
L. Tammilehto, Maritta Kilpeläinen, Henna Kupiainen, Tari Haahtela, Tarja Laitinen, Ari Lindqvist, Vuokko L. Kinnula, U Hodgson
Publikováno v:
COPD. 6(4)
This study aims to compare diagnostic and clinical outcomes of Chronic Obstructive Pulmonary Disease (COPD) from the gender perspective using retrospective health care data and patient reported outcomes in a real-world setting. An electronic database
Autor:
Nung Rudarakanchana, Markku Kupari, Nicholas W. Morrell, Marja Sankelo, Rachel E. Harrison, Richard C. Trembath, Rajiv D. Machado, Tarja Laitinen, Maija Halme, Anne Räisänen-Sokolowski, Juha Kere, Morgan Dixon, Julia A. Flanagan, Hannu Puolijoki, Outi Elomaa
Publikováno v:
Human mutation. 26(2)
In a nationwide study, we identified a total of 59 patients diagnosed with primary pulmonary hypertension (PPH) in Finland between the years 1987 and 1999. These data support a minimum estimate for a PPH population prevalence of 5.8 cases/million wit
Autor:
Sari Suomela, Erna Snellman, Jaakko Karvonen, Timo Reunala, Seija-Liisa Karvonen, Tarja Laitinen, Tutta Uurasmaa, Kati Asumalahti, Juha Kere, Christer T. Jansén, Ulpu Saarialho-Kere, Päivi Lahermo, Raija Itkonen-Vatjus
Publikováno v:
The Journal of investigative dermatology. 121(4)
The major susceptibility locus for psoriasis, PSORS1, resides on chromosome 6p and includes the candidate genes HLA-C, HCR, and CDSN. Based on a nationwide collection of psoriasis patients and genotyping for the PSORS1 susceptibility haplotype, we se
Publikováno v:
Europe PubMed Central
Linkage (genotypic) data from the 5q31-33 candidate region for asthma were contributed to Genetic Analysis Workshop 12 by members of the International Consortium on Asthma Genetics (COAG). Data came from five independent studies sampled from five cou
Autor:
Tarja Laitinen, Maija Mäntyjärvi
Publikováno v:
Journal of cataract and refractive surgery. 27(2)
Purpose To define normal values for the Pelli-Robson contrast sensitivity test in different age groups. Setting University Eye Clinic of Kuopio, Kuopio, Finland. Methods Contrast sensitivity was measured with the Pelli-Robson contrast sensitivity tes
Autor:
Raija Itkonen-Vatjus, Tarja Laitinen, Juha Kere, Marja-Liisa Lokki, Kati Asumalahti, Sari Suomela, Erna Snellman, Ulpu Saarialho-Kere
Publikováno v:
Human molecular genetics. 9(10)
A susceptibility gene for psoriasis, a chronic skin disorder, resides in chromosome 6p near the HLA-C locus. Sequencing of the region has allowed the identification of a new gene, HCR. We found that HCR is highly polymorphic with at least 12 coding v