Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Jane L. Grogan"'
Autor:
Ann Herman, Priscilla Horn, John C. Davis, Meina T. Tang, Carolyn Offutt, J Abraham Simon, Frank Hsieh, Michael J. Townsend, William P Kennedy, Jane L. Grogan
Publikováno v:
Arthritis Research & Therapy
Tumor necrosis factor (TNF) and, possibly, lymphotoxin alpha (LTα) signaling contribute to inflammation and rheumatoid arthritis (RA) pathogenesis. Pateclizumab (anti-lymphotoxin- alpha; MLTA3698A) is a humanized monoclonal antibody that blocks and
Autor:
David W. Dunne, Colin M. Fitzsimmons, T. J. Stewart, Karl F. Hoffmann, Jane L. Grogan, Maria Yazdanbakhsh
Publikováno v:
Parasite Immunology. 26:371-376
In Schistosoma mansoni and S. japonicum infection, the 22.6 kDa tegumental antigens Sm22.6 and Sj22.6 are principal targets for the human IgE response, and levels of IgE to Sm22.6 have been correlated with resistance to re-infection after chemotherap
Publikováno v:
The Journal of Infectious Diseases. 176:1344-1350
Specific IgG4 and IgE responses to adult worm antigen (AWA) and soluble egg antigen (SEA) were examined in 37 subjects from an area in which schistosomiasis is endemic, who were previously infected with Schistosoma haematobium and who became reinfect
Publikováno v:
European Journal of Immunology. 26:1365-1370
Cellular immune responses to schistosomal antigens were examined in 110 Schistosoma haematobium-infected individuals before and 5 weeks after treatment with praziquantel. Chemotherapy resulted in significant decrease in worm load as measured by egg o
Publikováno v:
The Journal of infectious diseases. 177(5)
Antigen-specific cellular immune responses were examined in persons previously infected with Schistosoma haematobium and who were, 2 years after chemotherapy, either free from infection (n = 17) or reinfected (n = 20). Proliferation to adult worm ant
Autor:
Hossam Ghoneim, Jane L. Grogan, André M. Deelder, Maria Yazdanbakhsh, Peter Rotmans, Mo-Quen Klinkert
Publikováno v:
Parasite immunology. 19(5)
Human schistosome infections are chronic in nature and elevated IgG4 levels are associated with length of exposure. To examine how structure, localization and dynamics of exposure of a protein to the immune system can affect antibody isotype expressi
Autor:
Maria Yazdanbakhsh, Jane L. Grogan, Wolfram G. Metzger, Benjamin Mordmüller, Peter G. Kremsner, A.M. Deelder, G.J. van Dam
Publikováno v:
The Journal of infectious diseases. 173(5)
Specific IgG4 and IgE responses and polyclonal cytokine profiles were studied in 110 Schistosoma haematobium-infected persons before and 5 weeks after chemotherapy. Pretreatment IgG4 responses to soluble egg antigen (SEA) correlated with intensity of