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Autor:
Cheng Cheng, Yinmei Zhou, Ching-Hon Pui, Matthew M. Klairmont, Tanja A. Gruber, Sima Jeha, John K. Choi, Hiroto Inaba, Yiwei Liu
Publikováno v:
Mod Pathol
Little is known about B-lymphoblastic leukemia (B-ALL) that lacks expression of terminal deoxynucleotidyl transferase (TdT). To address this, we performed the largest study to date of TdT-negative B-ALL using data from St. Jude Total XV and XVI clini
Autor:
Pimjai Niparuck, Pornnapa Police, Phichchapha Noikongdee, Kanchana Siriputtanapong, Nittaya Limsuwanachot, Budsaba Rerkamnuaychoke, Suporn Chuncharunee, Teerapong Siriboonpiputtana
Publikováno v:
Diagnostic Pathology, Vol 16, Iss 1, Pp 1-8 (2021)
Diagnostic Pathology
Diagnostic Pathology
Objectives TP53 mutation is found frequently in therapy related acute myeloid leukemia (AML)/ myelodysplastic syndrome (MDS), AML and MDS patients with monosomy or complex karyotype. However, the prevalence and treatment outcome in TP53 mutated AML/M
Publikováno v:
Patologìâ, Vol 18, Iss 2, Pp 167-173 (2021)
Aim. To stratify hemodynamic phenotypes in children with diabetes mellitus and their frequency, depending on the duration of the disease. Materials and methods. The study involved 72 children suffering from diabetes, aged 10 to 16 years who were divi
Autor:
Mingxiao Li, Weiwei Zhang, Xuzhe Zhao, Chuanwei Yang, Hongyan Chen, Ming Li, Lin Song, Kefu Yu, Xiaohui Ren, Gehong Dong, Haihui Jiang, Yong Cui, Qinghui Zhu
Publikováno v:
Cancer Science
Pyrosequencing (PSQ) represents the golden standard for MGMT promoter status determination. Binary interpretation of results based on the threshold from the average of several CpGs tested would neglect the existence of the “gray zone”. How to def
Autor:
Tomoko Horinouchi, Hiroki Hayashi, Tomohiko Yamamura, Koichi Nakanishi, Asami Takeda, Shinya Ishiko, Toshinori Ueno, China Nagano, Atsushi Kondo, Yuko Shima, Yuya Aoto, Akihito Tanaka, Sadayuki Nagai, Kazumoto Iijima, Masahiro Koizumi, Nana Sakakibara, Naoto Hamano, Kandai Nozu, Norishige Yoshikawa, Masayuki Hara, Takeshi Ninchoji
Publikováno v:
Clinical and Experimental Nephrology. 25(7):779-787
Background Pathological findings in Alport syndrome frequently show mesangial proliferation and sometimes incidental IgA deposition, in addition to unique glomerular basement membrane (GBM) changes including thin basement membrane and/or lamellation.
Autor:
Gang Zheng, Qi Shen, Wei Wang, Lina Shao, Lan Zheng, Ji Yuan, Young L. Kim, Guillermo Garcia-Manero, Yongzhong Yuan, Xiaohui Zhang, Xiaojun Wu, Rong He, L. Jeffrey Medeiros, Yulei Shen, Hong Fang, Sunyi Chi, Mariko Yabe, Sanam Loghavi, Shimin Hu, Peng Wei, Dong Chen, Guiling Tang
Publikováno v:
Modern Pathology. 34:1143-1152
t(6;9)(p22;q34.1)/DEK-NUP214 is a recurrent genetic abnormality that occurs in 1-2% of patients with acute myeloid leukemia (AML), and rarely in myelodysplastic syndrome (MDS). It has been suggested by others that all myeloid neoplasms with t(6;9)/DE
Publikováno v:
Türk Patoloji Dergisi, Vol 37, Iss 2, Pp 145-153 (2021)
Objective Acute Myeloid Leukemia (AML) and Acute Lymphoblastic Leukemia (ALL) are clinically and biologically diverse phenotypic diseases amongst hematological malignancies. The current study objectives were to diagnose and classify cases of AL as pe
Autor:
Anjanie Khimraj, Nora Katabi, Charles A Ghossein, Snjezana Dogan, Bin Xu, Wadad S Mneimneh, Bayan Alzumaili, Shenon Sethi, Ian Ganly
Publikováno v:
Head Neck Pathol
Oral squamous cell carcinoma (OSCC) occasionally occurs in young patients and is likely to be distinct from OSCC in older patients. In this retrospective study, we described the clinicopathologic features and outcome of 150 OSCCs that were diagnosed
Autor:
Hend Abdel-Nabi
Publikováno v:
Pediatric Rheumatology Online Journal, Vol 19, Iss 1, Pp 1-7 (2021)
Pediatric Rheumatology Online Journal
Pediatric Rheumatology Online Journal
BackgroundLupus podocytopathy (LP) is a renal affection described in systemic lupus erythematosus (SLE) patients with nephrotic range proteinuria, characterized by diffuse foot process effacement without immune deposits and glomerular proliferation.
Autor:
Nadir Kadri, Sarah J. Richardson, Lydia Sorokin, Eva Korpos, Sophie Loismann, Clais R. Findeisen, Noel G. Morgan, Alberto Pugliese, Frank Arfuso, George W. Burke, Marika Bogdani
Publikováno v:
Diabetologia
Aims/hypothesis We and others previously reported the presence of tertiary lymphoid organs (TLOs) in the pancreas of NOD mice, where they play a role in the development of type 1 diabetes. Our aims here are to investigate whether TLOs are present in