Zobrazeno 1 - 10
of 3 219
pro vyhledávání: ''
Autor:
Shunsuke Kimura, Lindsey Montefiori, Ilaria Iacobucci, Yaqi Zhao, Qingsong Gao, Elisabeth M. Paietta, Claudia Haferlach, A. Douglas Laird, Paul E. Mead, Zhaohui Gu, Wendy Stock, Mark Litzow, Jacob M. Rowe, Selina M. Luger, Stephen P. Hunger, Georgina L. Ryland, Breon Schmidt, Paul G. Ekert, Alicia Oshlack, Sean M. Grimmond, Jacqueline Rehn, James Breen, David Yeung, Deborah L. White, Ibrahim Aldoss, Elias J. Jabbour, Ching-Hon Pui, Manja Meggendorfer, Wencke Walter, Wolfgang Kern, Torsten Haferlach, Samuel Brady, Jinghui Zhang, Kathryn G. Roberts, Piers Blombery, Charles G. Mullighan
Publikováno v:
Blood
Transcriptome sequencing has identified multiple subtypes of B-progenitor acute lymphoblastic leukemia (B-ALL) of prognostic significance, but a minority of cases lack a known genetic driver. Here, we used integrated whole-genome (WGS) and -transcrip
Autor:
Lena Muckenthaler, Oriana Marques, Silvia Colucci, Joachim Kunz, Piotr Fabrowski, Thomas Bast, Sandro Altamura, Britta Höchsmann, Hubert Schrezenmeier, Monika Langlotz, Paulina Richter-Pechanska, Tobias Rausch, Nicole Hofmeister-Mielke, Nikolas Gunkel, Matthias W. Hentze, Andreas E. Kulozik, Martina U. Muckenthaler
Publikováno v:
Blood. 139:1418-1422
Muckenthaler et al describe a novel form of hemochromatosis caused by a constitutional PIGA mutation in 3 children with associated neurologic dysfunction. Hemochromatosis results from decreased hepcidin, which is regulated by HFE, hemojuvelin (HJV),
Autor:
Anna Wall, Herve Ghesquieres, Viola Poeschel, Jesse G. Dixon, Hervé Tilly, Marita Ziepert, Amy S. Ruppert, Qian Shi, David Cunningham, Norbert Schmitz, Christopher R. Flowers, Corinne Haioun, Jocelyne Flament, Gilles Salles
Great heterogeneity in survival exists for patients newly diagnosed with diffuse large B-cell lymphoma (DLBCL). Three scoring systems incorporating simple clinical parameters (age, lactate dehydrogenase, number/sites of involvement, stage, performanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b84f2887e4b5caa58b54159bae05ed
Autor:
Shanmuganathan Chandrakasan, Holly Edington, Manar Abdalgani, Jack J. Bleesing, Suhag Parikh, Michael H. White, Satheesh Chonat, Sunita Park, Sharat Chandra, Deepak Kumar, Michael Briones, Lisa Kobrynski, Sampath Prahalad, Carolyn M. Bennett, Rebecca A. Marsh, Laura Lucas, Athena Liza Russell, Sara H Graciaa, Kiran Patel, Edmund K. Waller, Chengyu Prince
Publikováno v:
Blood
Pediatric Evans syndrome (pES) is increasingly identified as the presenting manifestation of several inborn errors of immunity. Despite an improved understanding of genetic defects in pES, the underlying immunobiology of pES is poorly defined, and ch
Autor:
Bernard Ng, Henrique Bittencourt, Jacob Rozmus, Kimberly A. Kasow, Benjamin Oshrine, Michael A. Pulsipher, Anna B. Pawlowska, David A. Jacobsohn, Kirk R. Schultz, Victor Lewis, Ramon I. Klein Geltink, Madeline Lauener, Sayeh Abdossamadi, Joseph H. Chewning, Tal Schechter, Carrie L. Kitko, Geoffrey D.E. Cuvelier, Gail Megason, Sung Won Choi, Andrew C. Harris, Elena Ostroumov, Don W. Coulter, Amina Kariminia, Michael Joyce, Monica Bhatia, Eneida R. Nemecek, Emi Caywood, Anita Lawitschka, Divya Subburaj, Sandhya Kharbanda
Publikováno v:
Blood. 139:287-299
Chronic graft-versus-host disease (cGVHD) is the most common cause for non-relapse mortality postallogeneic hematopoietic stem cell transplant (HSCT). However, there are no well-defined biomarkers for cGVHD or late acute GVHD (aGVHD). This study is a
Autor:
Megumu Fujihara, Noriaki Yoshida, Ritsu Sakata, Kiyohiko Mabuchi, Dale L. Preston, Kotaro Ozasa
Publikováno v:
Blood
Epidemiological data have provided limited and inconsistent evidence on the relationship between radiation exposure and lymphoid neoplasms. We classified 553 lymphoid neoplasm cases diagnosed between 1950 and 1994 in the Life Span Study cohort of ato
Autor:
Laura Pardo, Alan S. Gamis, Michael R. Loken, Lisa Eidenschink Brodersen, E. Anders Kolb, William G. Woods, Jenny L. Smith, Todd Cooper, Tiffany A. Hylkema, Todd A. Alonzo, Richard Aplenc, Rhonda E. Ries, Katherine Tarlock, Yi-Cheng Wang, Amanda R. Leonti, Robert B. Gerbing, Soheil Meshinchi, Adam J. Lamble
Publikováno v:
Blood
Biallelic CEBPA mutations are associated with favorable outcomes in acute myeloid leukemia (AML). We evaluated the clinical and biologic implications of CEBPA-basic leucine zipper (CEBPA-bZip) mutations in children and young adults with newly diagnos
Autor:
Marie Robin, Liesbeth C. de Wreede, Eric Padron, Katerina Bakunina, Pierre Fenaux, Linda Koster, Aziz Nazha, Dietrich W. Beelen, Raajit K. Rampal, Katja Sockel, Rami S. Komrokji, Nico Gagelmann, Dirk-Jan Eikema, Aleksandar Radujkovic, Jürgen Finke, Victoria Potter, Sally B. Killick, Faezeh Legrand, Eric Solary, Angus Broom, Guillermo Garcia-Manero, Vittorio Rizzoli, Patrick Hayden, Mrinal M. Patnaik, Francesco Onida, Ibrahim Yakoub-Agha, Raphael Itzykson
Publikováno v:
Blood, 140(12), 1408-1418. AMER SOC HEMATOLOGY
To determine the survival benefit of allogeneic hematopoietic cell transplantation (allo-HCT) in chronic myelomonocytic leukemias (CMML), we assembled a retrospective cohort of CMML patients 18-70 years old diagnosed between 2000 and 2014 from an int
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63de466d5e61bdb9ee22dd9315c2f65c
https://hdl.handle.net/1887/3564265
https://hdl.handle.net/1887/3564265
Autor:
Kazuyoshi Hosomichi, Yoshitaka Zaimoku, Takamasa Katagiri, Kohei Hosokawa, Takeshi Yoroidaka, Ken Ishiyama, Hiroyuki Takamatsu, Atsushi Tajima, Hirohito Yamazaki, Shinji Nakao, Tatsuya Imi, Mikoto Tanabe, Mai Anh Thi Nguyen, Dung Cao Tran, Fumihiro Azuma, Ryota Urushihara, Noriaki Tsuji, Hiroki Mizumaki, Hiroyuki Maruyama, Seishi Ogawa
Publikováno v:
Blood. 137:3576-3580
Autor:
Tao Wang, Helen E. Heslop, Stephen Gottschalk, Bambi Grilley, Rammurti T. Kamble, Carlos A. Ramos, Ann M. Leen, Meng-Fen Wu, Malcolm K. Brenner, Robert A. Krance, Catherine Robertson, Manik Kuvalekar, Jasleen K. Randhawa, Spyridoula Vasileiou, Adrian P. Gee, Suhasini Lulla, Juan F. Vera, Betty Chung, Ayumi Watanabe, Premal Lulla, Ifigeneia Tzannou, Swati Naik, LaQuisa Hill, George Carrum
Publikováno v:
Blood
Relapse after allogeneic hematopoietic stem cell transplantation (HCT) is the leading cause of death in patients with acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS). Infusion of unselected donor lymphocytes (DLIs) enhances the graft-v