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Autor:
Anna Wall, Herve Ghesquieres, Viola Poeschel, Jesse G. Dixon, Hervé Tilly, Marita Ziepert, Amy S. Ruppert, Qian Shi, David Cunningham, Norbert Schmitz, Christopher R. Flowers, Corinne Haioun, Jocelyne Flament, Gilles Salles
Great heterogeneity in survival exists for patients newly diagnosed with diffuse large B-cell lymphoma (DLBCL). Three scoring systems incorporating simple clinical parameters (age, lactate dehydrogenase, number/sites of involvement, stage, performanc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86b84f2887e4b5caa58b54159bae05ed
Autor:
Hongseok Yun, Seung Hong Choi, Ka Young Lim, Seung-Ki Kim, Yumi Shim, Tae Min Kim, Jin-Woo Park, Hyunhee Kim, Jeongwan Kang, Sung Hye Park, Chul-Kee Park, Kwanghoon Lee, Jae Kyung Won
Publikováno v:
Laboratory Investigation; a Journal of Technical Methods and Pathology
Mismatch repair-deficient (MMRD) brain tumors are rare among primary brain tumors and can be induced by germline or sporadic mutations. Here, we report 13 MMRD-associated (9 sporadic and 4 Lynch syndrome) primary brain tumors to determine clinicopath
Autor:
Shanmuganathan Chandrakasan, Holly Edington, Manar Abdalgani, Jack J. Bleesing, Suhag Parikh, Michael H. White, Satheesh Chonat, Sunita Park, Sharat Chandra, Deepak Kumar, Michael Briones, Lisa Kobrynski, Sampath Prahalad, Carolyn M. Bennett, Rebecca A. Marsh, Laura Lucas, Athena Liza Russell, Sara H Graciaa, Kiran Patel, Edmund K. Waller, Chengyu Prince
Publikováno v:
Blood
Pediatric Evans syndrome (pES) is increasingly identified as the presenting manifestation of several inborn errors of immunity. Despite an improved understanding of genetic defects in pES, the underlying immunobiology of pES is poorly defined, and ch
Autor:
Bernard Ng, Henrique Bittencourt, Jacob Rozmus, Kimberly A. Kasow, Benjamin Oshrine, Michael A. Pulsipher, Anna B. Pawlowska, David A. Jacobsohn, Kirk R. Schultz, Victor Lewis, Ramon I. Klein Geltink, Madeline Lauener, Sayeh Abdossamadi, Joseph H. Chewning, Tal Schechter, Carrie L. Kitko, Geoffrey D.E. Cuvelier, Gail Megason, Sung Won Choi, Andrew C. Harris, Elena Ostroumov, Don W. Coulter, Amina Kariminia, Michael Joyce, Monica Bhatia, Eneida R. Nemecek, Emi Caywood, Anita Lawitschka, Divya Subburaj, Sandhya Kharbanda
Publikováno v:
Blood. 139:287-299
Chronic graft-versus-host disease (cGVHD) is the most common cause for non-relapse mortality postallogeneic hematopoietic stem cell transplant (HSCT). However, there are no well-defined biomarkers for cGVHD or late acute GVHD (aGVHD). This study is a
Autor:
Megumu Fujihara, Noriaki Yoshida, Ritsu Sakata, Kiyohiko Mabuchi, Dale L. Preston, Kotaro Ozasa
Publikováno v:
Blood
Epidemiological data have provided limited and inconsistent evidence on the relationship between radiation exposure and lymphoid neoplasms. We classified 553 lymphoid neoplasm cases diagnosed between 1950 and 1994 in the Life Span Study cohort of ato
Autor:
Gerard Dijkstra, Marijn C. Visschedijk, Remco J. Renken, Henk J. Buikema, Marco R. de Groot, Jacco J de Haan, Mathilde Jalving, Gursah Kats-Ugurlu, Sara Hone Lopez
Publikováno v:
Virchows Archiv
Virchows Archiv : an International Journal of Pathology, 479(6), 1119-1129. SPRINGER
Virchows Archiv : an International Journal of Pathology, 479(6), 1119-1129. SPRINGER
Colitis is a common, but poorly understood, adverse event of immune checkpoint inhibitors that are standard-of-care for an expanding range of cancer types. This explorative study aimed to describe the immune infiltrates in the colon from individuals
Autor:
Karen T Elvers, Maia Kavanagh Williamson, Massimo Caputo, Darryl J. Hill, Paolo Madeddu, Andrew D. Davidson, Elisa Avolio, Imre Berger, Rachel Milligan, Kapil Gupta, David T Arnold, Michele Carrabba, Fergus Hamilton, Rebecca R. Foster, Kathleen M Gillespie, Monica Gamez, Antonio Paolo Beltrami
Publikováno v:
Avolio, E, Carrabba, M, Milligan, R, Kavanagh Williamson, M, Beltrami, A P, Gupta, K, Elvers, K T, Gamez, M, Foster, R R, Gillespie, K M, Hamilton, F W, Arnold, D T, Berger, I, Davidson, A D, Hill, D J, Caputo, M & Madeddu, P R 2021, ' The SARS-CoV-2 Spike protein disrupts human cardiac pericytes function through CD147-receptor-mediated signalling : a potential non-infective mechanism of COVID-19 microvascular disease ', Clinical Science, vol. 135, no. 24, CS20210735, pp. 2667-2689 . https://doi.org/10.1042/CS20210735
Severe coronavirus disease 2019 (COVID-19) manifests as a life-threatening microvascular syndrome. The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses the Spike (S) protein to engage with its receptors and infect host cells. To date
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Scientific Reports
Scientific Reports
In human gliomas, anti-tumor T cell responses are inhibited through induction of local and systemic immunosuppression. Immune checkpoint blockade is proving to be a success in several types of cancers. However, many studies reported that the treatmen
Autor:
Endre Kálmán, Nikoletta Nagy, András L. Kovács, Leila Youssefian, Sarolta Kárpáti, Jouni Uitto, Amir Hossein Saeidian, Ágnes Kinyó, Péter Degrell, Hassan Vahidnezhad, Rolland Gyulai
Publikováno v:
Journal of Investigative Dermatology. 141:2752-2756
Autor:
Zhigang Tian, Xiaokun Shen, Rui Sun, Chuang Guo, Binqing Fu, Haiming Wei, Jiabin Li, Dongyao Wang, Ying Ye, Junfei Zhang, Yanyan Liu
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 6, Iss 1, Pp 1-13 (2021)
Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy
Patients with chronic hepatitis B (CHB) undergoing interferon (IFN)-α-based therapies often exhibit a poor HBeAg serological response. Thus, there is an unmet need for new therapies aimed at CHB. This study comprised two clinical trials, including 1