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Autor:
Yan Yuan, Zhifan Zeng, Rong-Zhen Li, Weiwei Xiao, Hui Chang, Qiaoxuan Wang, Yuanhong Gao, Wei-Hao Xie
Publikováno v:
Cancer Medicine, Vol 11, Iss 1, Pp 117-127 (2022)
Cancer Medicine
Cancer Medicine
Background Anal squamous cell carcinoma (ASCC) is a rare malignant tumor with increasing incidence. The goal of our study was to analyze the treatment outcome and prognostic factors of ASCC in South China in the past half‐century. Methods This stud
Autor:
Tina Pesaran, Jeffrey N. Weitzel, Clarice R. Weinberg, Chi Gao, Susan L. Neuhausen, Eric C. Polley, Alpa V. Patel, Christopher A. Haiman, Christine B. Ambrosone, Celine M. Vachon, Hongyan Huang, Sara Lindstrom, Julie R. Palmer, Esther M. John, Jill S. Dolinsky, Leslie Bernstein, Rohan Gnanaolivu, Allison W. Kurian, Steven N. Hart, Holly LaDuca, Hoda Anton-Culver, Janet E. Olson, Chunling Hu, Amal Yussuf, Song Yao, Nicole L. Larson, Peter Kraft, Jie Na, Fergus J. Couch, Nicholas J. Boddicker, Elena Martinez, Amy Trentham-Dietz, Siddhartha Yadav, Paul W. Auer, Dale R Sandler, Elizabeth C. Chao, Susan M. Domchek, Rachid Karam, Katherine L. Nathanson, James V. Lacey, Jack A. Taylor, David E. Goldgar
Publikováno v:
J Clin Oncol
PURPOSE To determine the contribution of germline pathogenic variants (PVs) in hereditary cancer testing panel genes to invasive lobular carcinoma (ILC) of the breast. MATERIALS AND METHODS The study included 2,999 women with ILC from a population-ba
Autor:
Zahra Madjd, Mahdieh Razmi, Sima Saki, Elham Kalantari, Leili Saeednejad Zanjani, Monireh Mohsenzadegan, Fahimeh Fattahi, Maryam Abolhasani
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 148:609-631
Melanoma-associated antigen A2 (MAGE-A2) is a member of the cancer-testis antigen family differentially overexpressed in a variety of malignancies and is associated with tumor development. However, clinical significance and prognostic value of MAGE-A
Autor:
Shannon Gallagher, Jeffrey N. Weitzel, Eric Rosenthal, Placede Tshiaba, Danna F. Grear, Jerry S. Lanchbury, Judy Garber, Susanne Wagner, Benjamin B. Roa, Wade Hedegard, Kathryn Dalton, Mark E. Robson, Johnathan M. Lancaster, Alexander Gutin, Allison W. Kurian, Susan M. Domchek, Elisha Hughes, Thaddeus Judkins, Carol A. Adami, Stephanie Meek
Publikováno v:
JCO Precision Oncology
PURPOSE Screening and prevention decisions for women at increased risk of developing breast cancer depend on genetic and clinical factors to estimate risk and select appropriate interventions. Integration of polygenic risk into clinical breast cancer
Autor:
Zhidan Zhang, Kaidi Song, Guangyu Sun, Baolin Tang, Meijuan Tu, Wen Yao, Xiaoyu Zhu, Tianzhong Pan, Liangquan Geng, Zimin Sun, Huilan Liu, Xiang Wan, Peng Ding, Yue Wu, Ping Qiang
Publikováno v:
Hematological Oncology. 40:83-92
Prolonged isolated thrombocytopenia (PIT) is a common complication after umbilical cord blood transplantation (UCBT). However, data on PIT prediction and impacts on transplantation outcomes for UCBT patients are rare. We retrospectively analyzed 244
Autor:
Andrew Wishart, M. Iqbal Parker, Pauline J. van der Watt, Jonathan M. Blackburn, Virna D. Leaner, Nelson C. Soares, Michael O. Okpara
Publikováno v:
International Journal of Cancer. 150:347-361
Previous studies have identified increased expression of members of the nuclear transport protein family in cancer cells. Recently, certain nuclear transport proteins have been reported to be secreted by cells and found in the serum. The aims of our
Autor:
Seock-Ah Im, Jee Hyun Kim, Jin-Young Jang, Do-Youn Oh, Sae-Won Han, Yung-Jue Bang, Sung W. Ha, Sun Whe Kim, Jihyun Kwon, Eui Kyu Chie, Jae Sung Kim, Tae-You Kim, Kyung-Hun Lee
Publikováno v:
Cancer Research and Treatment : Official Journal of Korean Cancer Association
Purpose Despite curative resection, the 5-year survival for patients with resectable pancreatic cancer is less than 20%. Recurrence occurs both locally and at distant sites and effective multimodality adjuvant treatment is needed.Materials and Method
Autor:
Nassim Djebli, Pierre-Olivier Tremblay, Vincent Buchheit, Mario González-Sales, Guillaume Bonnefois, Georgina Meneses-Lorente, Francois Mercier, Nicolas Frey
Publikováno v:
Cancer Chemotherapy and Pharmacology. 88:997-1007
Entrectinib (ROZLYTREK®) is a CNS-active, potent, and selective inhibitor of ROS1, TRK A/B/C, and ALK kinase activity. It was recently approved for the treatment of ROS1-positive non-small cell lung cancer and NTRK gene fusion-positive solid tumors.
Publikováno v:
International Journal of Cancer. 150:18-27
H. pylori (H. pylori) infection is considered the leading cause of gastric cancer. Gastric cancer is currently a common cancer with high incidence and mortality rates, but it is expected that the incidence rate will gradually decrease as the H. pylor
Autor:
Xavier Quantin, Nicolas Girard, Marylise Ginoux, Luc Thiberville, Benjamin Besse, Christelle Clément-Duchêne, P.A. Thomas, P. Mordant, Angela Botticella, C. Le Pechoux, J. Khalifa, Eric Pichon, Thierry Jo Molina, F. Le Tinier, Youssef Oulkhouir, Mallorie Kerjouan, Clémence Basse, Pierre Emmanuel Falcoz, F. Thillays, Virginie Westeel
Publikováno v:
Clinical Lung Cancer
Clinical Lung Cancer, Elsevier, 2021, ⟨10.1016/j.cllc.2021.01.020⟩
Clinical Lung Cancer, Elsevier, 2021, ⟨10.1016/j.cllc.2021.01.020⟩
Introduction Thymomas are rare intrathoracic malignancies that may be aggressive and difficult to treat. Knowledge and level of evidence for treatment strategies are mainly based on retrospective studies or expert opinion. Currently there is no stron