Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Tetsuya Hosooka"'
Autor:
Kei Yoshino, Yuko Nabatame, Masakazu Shinohara, Kazuhiro Nomura, Yoshitake Hayashi, Kaku Matsugi, Wataru Ogawa, Kanji Yamaguchi, Hiroshi Sakaue, Tsutomu Sasaki, Sho Matsui, Tadahiro Kitamura, Yusei Hosokawa, Takehiko Yokomizo, Yoshikazu Tamori, Jun Nakae, Domenico Accili, Tetsuya Hosooka, Masato Kasuga, Chikako Aoki, Yoko Senga, Susumu Seino, Masashi Kuroda, Yoshito Itoh
Publikováno v:
Proceedings of the National Academy of Sciences. 117:11674-11684
Although adipocytes are major targets of insulin, the influence of impaired insulin action in adipocytes on metabolic homeostasis remains unclear. We here show that adipocyte-specific PDK1 (3'-phosphoinositide-dependent kinase 1)-deficient (A-PDK1KO)
Autor:
Wataru Ogawa, Tetsuya Hosooka
Publikováno v:
Diabetes. 67
Although adipocytes are major targets of insulin, the influence of impaired insulin action in adipocytes on metabolic homeostasis has been unclear. To provide insight into the role of insulin action in adipocytes, we generated mice that lack 3'-phosp
Publikováno v:
Journal of Diabetes Investigation
Insulin resistance, a key feature of type 2 diabetes, contributes to a variety of pathological conditions including dyslipidemia, hypertension, atherosclerosis, cognitive disorders and cancer. Obesity, defined as increased lipid deposition in adipose