Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Wayne B. Anderson"'
Publikováno v:
Experimental Cell Research. 129:466-469
Hormonal responsiveness of the adenylate cyclase system of cultured F9 teratocarcinoma cells was investigated. Of numerous hormones tested only calcitonin, (−)isoproterenol, and prostaglandin E1, stimulate F9 adenylate cyclase activity. Of the acti
Autor:
M.Olivia Pinkett, Wayne B. Anderson
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 714:337-343
Incubation of crude normal rat kidney membranes with activated cholera toxin in the presence of GTP, ATP and NAD+ results in a 10–20-fold stimulation of adenylate cyclase activity. Optimal choleragen activation of the cyclase is shown to be depende
Publikováno v:
Biochemical and Biophysical Research Communications. 90:1159-1165
Summary A rat kidney cortex lysosomal protease [Strewler, G. J., Manganiello, V. C. and Vaughan, M. (1977) J. Biol. Chem. 253, 390–394] which activates cyclic nucleotide phosphodiesterases has been shown to potentiate adenylate cyclase activity in
Publikováno v:
Journal of Cellular Physiology. 109:453-459
Teratocarcinoma cells in culture offer an in vitro system for studying certain aspects of embryonic differentiation. To gain some insight into regulatory systems that might be operative during early development, we have characterized the alterations
Publikováno v:
Journal of Biological Chemistry. 255:7716-7721
Publikováno v:
Proceedings of the National Academy of Sciences. 70:3802-3805
To investigate how cell population density influences the intracellular concentration of cyclic AMP we have measured adenylate cyclase and cyclic AMP phosphodiesterase activities and cyclic AMP levels at various stages of cell density in normal rat-k
Publikováno v:
Experimental Cell Research. 120:47-53
The addition of the somatomedin-like growth factor Multiplication Stimulatory Activity (MSA) to intact chick embryo fibroblasts (CEF) in culture does not decrease the basal intracellular pool of cAMP. As a more sensitive means of determining a possib
Publikováno v:
Journal of Biological Chemistry. 249:7041-7048
The activity of the enzyme adenylate cyclase has been determined in normal rat kidney (NRK) cells and NRK cells transformed by either the Kirsten sarcoma virus (Ki-SV) or the Moloney sarcoma virus (Mo-SV). The specific activity of the NRK enzyme incr
Publikováno v:
Biochemical and Biophysical Research Communications. 52:1293-1299
Chick embryo fibroblasts (CEF) transformed by the Schmidt-Ruppin strain of Rous sarcoma virus (RSV-SR) have decreased adenylate cyclase activity. In cells infected by a temperature-sensitive mutant of this virus (RSV-SR-T5), enzyme activity is near n
Publikováno v:
Journal of Biological Chemistry. 254:5588-5590
The ability of prostaglandin E1 (PGE1) and cholera toxin to increase cyclic AMP levels is potentiated 6-fold when normal rat kidney (NRK) cells are treated with picolinic acid or histidinol, or grown in isoleucine-deficient medium. The response to (-