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pro vyhledávání: '"Katrina Sweeney"'
Autor:
Gunnel Halldén, Celina Costas, Eva Yanover, Virginie Adam, Nicholas R. Lemoine, Daniel Öberg, Katrina Sweeney
Publikováno v:
Clinical Cancer Research. 16:541-553
Purpose: Replication-selective oncolytic adenoviruses are a promising class of tumor-targeting agents with proven safety in hundreds of patients. However, clinical responses have been limited and viral mutants with higher potency are needed. Here, we
Autor:
Daniel Öberg, Enrique Miranda, Nicholas R. Lemoine, Gunnel Halldén, Katrina Sweeney, Derek Davies, Stephan Leitner
Publikováno v:
Clinical Cancer Research. 15:1730-1740
Purpose: Pancreatic adenocarcinoma is a rapidly progressive malignancy that is highly resistant to current chemotherapeutic modalities and almost uniformly fatal. We show that a novel targeting strategy combining oncolytic adenoviral mutants with the