Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Islam, M. D."'
Autor:
Sadakane K; Department of Bioinformatics, Graduate School of Engineering Soka University, 1-236 Tangi-cho, Hachioji, Tokyo, Japan., Alrazi IMD; Department of Bioinformatics, Graduate School of Engineering Soka University, 1-236 Tangi-cho, Hachioji, Tokyo, Japan., Maruta S; Department of Bioinformatics, Graduate School of Engineering Soka University, 1-236 Tangi-cho, Hachioji, Tokyo, Japan.
Publikováno v:
Journal of biochemistry [J Biochem] 2018 Oct 01; Vol. 164 (4), pp. 295-301.
Autor:
Olaposi I Omotuyi, Shinsaku Maruta, Ayodele O. Kolawole, Islam M D Alrazi, Olusola Olalekan Elekofehinti, Takayuki Miyanishi, Tomisin H Ogunwa
Publikováno v:
Journal of biochemistry. 170(5)
Mitotic kinesin Eg5 remains a validated target in antimitotic therapy because of its essential role in the formation and maintenance of bipolar mitotic spindles. Although numerous Eg5 inhibitors of synthetic origin are known, only a few inhibitors de
Publikováno v:
Journal of biochemistry. 170(2)
The mitotic kinesin Eg5 is a plus-end directed homotetrameric molecular motor essential for the formation of bipolar spindles during cell division. Kinesin Eg5 is overexpressed in cancer cells and hence considered as a target for cancer therapy; the
Publikováno v:
Journal of biochemistry. 164(4)
Mitotic kinesin Eg5 plays an important physiological role in cell division. Several small-molecule inhibitors of Eg5 are the focus of cancer therapies. Azobenzene is a photochromic compound exhibiting cis-trans isomerization upon ultraviolet (UV) and