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Autor:
Paul Mitchell, G Rivalland, Hui Yu, Fred R. Hirsch, R. Mosher, L Churilov, K Asadi, Christopher J. Rivard, S Heynemann
Publikováno v:
Clinical Lung Cancer. 23:e90-e98
Background NaPi2b is a multi-transmembrane sodium-dependent phosphate transporter expressed at normal levels in several organs, including lung. High expression levels have been reported in various tumours including breast, thyroid, ovarian and non-sm
Autor:
Sebastian F. Schoppmann, Emmanuella Guenova, Gerd Jomrich, Matthias Preusser, Robin Ristl, Dariga Ramazanova, Aysegül Ilhan-Mutlu, Richard Grose, Christina Fassnacht, Dagmar Kollmann, Yi-Chien Tsai
Publikováno v:
European Journal of Surgical Oncology. 48:383-390
The effects of cytotoxic chemotherapy on the expression of programmed cell death 1 (PD-1) and its ligand (PD-L1) in cancer cells and peritumoral cells are unclear. The aim of this study was to investigate the impact of neoadjuvant chemotherapy on PD-
Publikováno v:
Human Pathology. 119:51-58
Oncogenic mutations in the adenomatous polyposis coli (APC)/Wnt signaling pathway are well documented. The FBXW7 gene (F-box and WD repeat domain-containing 7) encodes a member of the ubiquitin-proteasome complex that is more recently described to an
Publikováno v:
European Journal of Surgical Oncology. 48:211-217
Background Microsatellite instability, programmed death-ligand 1 and tumor-infiltrating leukocytes are prognostic biomarkers in colorectal cancer but unknown toward familial adenomatous polyposis. Aim To investigate the prognostic and clinicopatholog
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 148:565-575
Purpose: NRAS plays a pivotal role in progression of various kinds of somatic malignancies; however, the correlation between NRAS and lung adenocarcinoma is less known. We aim to analyze the prognostic value of NRAS expression in lung adenocarcinoma,
Publikováno v:
J Histochem Cytochem
Non-ampullary duodenal adenocarcinoma (DAC) is a rare malignancy. Little information is available concerning the histopathological prognostic factors associated with DAC. Carbonic anhydrases (CAs) are metalloenzymes catalyzing the universal reaction
Publikováno v:
Modern Pathology. 34:1738-1749
Invasive stratified mucin-producing carcinoma (ISMC) is a recently described entity of human papillomavirus (HPV)-associated endocervical adenocarcinoma with phenotypic plasticity and aggressive clinical behavior. To identify the cell of origin of IS
Autor:
Feng Gao, Shirong Huang, Guozhong Liu, Wei Lian, Sheng Zhang, Xiangqun Fan, Yujia Guo, Qicai Liu, Xiaoting Lv, Fadian Ding, Jingwen Wang
Publikováno v:
Oxidative Medicine and Cellular Longevity, Vol 2021 (2021)
Oxidative Medicine and Cellular Longevity
Oxidative Medicine and Cellular Longevity
Calcitonin gene-related peptide (CGRP) plays a diverse and intricate role in chronic low-grade inflammation and is closely related to specific cancers. It includes two subtypes, CALCA (αCGRP) and CALCB (βCGRP), of which αCGRP expression accounts f
Autor:
Mai Iwaya, Tomoyuki Nakajima, Takayuki Watanabe, Yusuke Miyagawa, Yasuhiro Kinugawa, Takeshi Uehara, Takashi Muraki, Yasuhiro Kuraishi, Takeji Umemura
Publikováno v:
Diagnostic Pathology, Vol 16, Iss 1, Pp 1-8 (2021)
Diagnostic Pathology
Diagnostic Pathology
Background Pancreaticobiliary maljunction (PBM) is a condition characterized by chronic inflammation due to refluxed pancreatic juice into the biliary tract that is associated with an elevated risk of biliary tract cancer. DNA double-strand breaks (D
Autor:
Hiroshi Yagi, Yuki Masuda, Taizo Hibi, Naoto Kubota, Hidenori Ojima, Yoko Fujii-Nishimura, Yuta Abe, Masahiro Shinoda, Minoru Kitago, Yasushi Hasegawa, Go Oshima, Yuko Kitagawa, Shutaro Hori, Michiie Sakamoto, Yusuke Takemura
Publikováno v:
Cancer Medicine, Vol 10, Iss 16, Pp 5599-5613 (2021)
Cancer Medicine
Cancer Medicine
Gamma‐synuclein (SNCG) promotes invasive behavior and is reportedly a prognostic factor in a range of cancers. However, its role in biliary tract carcinoma (BTC) remains unknown. Consequently, we investigated the clinicopathological significance an