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Autor:
Janos Szederjesi, László Kóbori, Ioan Jung, Decebal Fodor, Haruhiko Sugimura, Simona Gurzu, Rita Szodorai, Cornelia Braicu
Publikováno v:
Histochemistry and Cell Biology. 156:377-390
In hepatocellular carcinomas (HCCs), the role of the cell surface protein V-set and immunoglobulin domain containing 1 (VSIG1), which is known as a specific marker of the gastric mucosa and testis, has not yet been determined. We examined VSIG1 immun
Autor:
Junyi Ye, Shanai Song, Haiwei Du, Zhou Zhang, Haiyan Li, Ning Liu, Zimin Liu, Xiaoxiao Li, Lu Zhang, Mingpeng Shi
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose The identification of HER2 overexpression in a subset of gastric adenocarcinoma (GA) patients represents a significant step forward in unveiling the molecular complexity of this disease. The predictive and prognostic value of HER2 amplificati
Autor:
Kenichi Urakami, Takashi Sugino, Keiichi Fujiya, Takeshi Nagashima, Kenichi Nakamura, Keiichi Ohshima, Yasuto Akiyama, Yasuhiro Tsubosa, Ken Yamaguchi, Yuko Kitagawa, Masakuni Serizawa, Daisuke Aizawa, Masanori Terashima, Keiichi Hatakeyama
Publikováno v:
Gastric Cancer. 24:341-351
Resection for hepatic recurrence after gastrectomy in patients with gastric cancer may be curative; however, the prediction of hepatic recurrence remains intractable. Therefore, we aimed to explore predictive markers for hepatic recurrence in gastric
Autor:
Laura Lehtinen, Raija Ristamäki, Vanina D. Heuser, Annika Ålgars, Eva-Maria Birkman, Olli Carpén, Naziha Mansuri, Minnamaija Lintunen, Jari Sundström
Publikováno v:
Virchows Archiv
While host immune response is likely to be important for the prognosis of gastric cancer patients, detailed information on the T lymphocyte infiltration in different gastric cancer subtypes is lacking. Here, we studied the presence of CD3, CD8, and F
Autor:
Ki-Chul Hwang, Sang Woo Kim, Jung-Won Choi, Seongtae Jeong, Woon Yong Jung, Yong Chan Lee, Yu Jin Kim
Publikováno v:
International Journal of Medical Sciences
In our previous study, we identified three miRNAs (hsa-miR-421, hsa-miR-29b-1-5p, and hsa-miR-27b-5p) with two mRNAs (FBXO11 and CREBZF) that might play an important role in the development of gastric adenocarcinoma (GAC) from premalignant adenomas.
Autor:
Go Eun Bae, Min-Kyung Yeo, Kyung-Hee Kim, Sang-Il Lee, Tae Hee Lee, In Sun Kwon, Ju Seok Kim, Chaeuk Chung, Dahye Lee
Publikováno v:
Anticancer Research. 39:6711-6722
Background/aim Autophagy is a cellular mechanism that recycles cellular components to maintain homeostasis. To investigate the clinical implication of autophagy in gastric cancer, the autophagy markers with autophagosome formation, LC3B and selective
Autor:
Masoud Sotoudeh, Ramin Shakeri, Mahmood Naderi, Sanford M. Dawsey, Naser Ahmadbeigi, Bahareh Sharififard
Publikováno v:
Cancer Immunol Immunother
BACKGROUND. Despite the promise of immunotherapy for gastric adenocarcinoma, choices for the selection of effective antigenic targets are very limited. Previously published data and our own in-house computational analysis have suggested that ANTXR1 i
Autor:
Rosine Guimbaud, Carlos Gomez-Roca, Laurent Mineur, Thomas Aparicio, Emmanuelle Samalin, Gilles Vassal, Jannick Selves, Christelle De La Fouchardiere, Paul Arthur Haineaux, Yves Menu, Florence Mary, Alain Gratet, Nathalie Cozic, N. Colignon, Jérôme Edouard Plaza, Laetitia Johnson, Frédéric Legrand, Emeline Meriaux, Thierry Lecomte
Publikováno v:
Targeted Oncology
Targeted Oncology, 2021, ⟨10.1007/s11523-021-00811-8⟩
Targeted Oncology, Springer Verlag (Germany), 2021, ⟨10.1007/s11523-021-00811-8⟩
Targeted Oncology, 2021, ⟨10.1007/s11523-021-00811-8⟩
Targeted Oncology, Springer Verlag (Germany), 2021, ⟨10.1007/s11523-021-00811-8⟩
Background The AcSé-crizotinib program provides extensive screening of crizotinib-targeted genomic alteration in several malignancies. We here report the results in patients with esogastric MET-amplified adenocarcinomas. Objective The objective of t
Publikováno v:
American Journal of Clinical Pathology. 152:517-526
Objectives Our goal was to assess the expression of histone acetyltransferase binding to origin recognition complex 1 (HBO1) in gastric cancer and the effect on prognosis for the patients. Methods We used quantitative reverse transcription polymerase
Publikováno v:
Am J Surg Pathol
BACKGROUND: Immune checkpoint inhibition is effective in a subset of patients with advanced gastric cancer. Genomic profiling has revealed the heterogeneity of gastric adenocarcinomas, but the immune microenvironment and predictors of immunotherapy r