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Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 23, Iss 6, Pp 584-593 (2021)
Neoplasia (New York, N.Y.)
Neoplasia (New York, N.Y.)
The most prevalent histological type of non-small cell lung cancer (NSCLC) is adenocarcinoma. The WHO classifies this tumor into subtypes according to the predominant growth pattern such as lepidic, acinar, papillary, solid or micropapillary, each ha
Targeting CXCR2 inhibits the progression of lung cancer and promotes therapeutic effect of cisplatin
Autor:
Yuan Cheng, Xuejiao Han, Qingfang Li, Fei Mo, Xiawei Wei, Yuquan Wei, Houhui Shi, Siyuan Chen
Publikováno v:
Molecular Cancer, Vol 20, Iss 1, Pp 1-21 (2021)
Molecular Cancer
Molecular Cancer
Background Drug-resistance and severe side effects of chemotherapeutic agents result in unsatisfied survival of patients with lung cancer. CXCLs/CXCR2 axis plays an important role in progression of cancer including lung cancer. However, the specific
Autor:
Audrey J. Lazenby, Chandrakanth Are, Lynette M. Smith, Michael G. Brattain, Premila D. Leiphrakpam
Publikováno v:
Journal of Surgical Oncology. 123:1764-1772
OBJECTIVES To evaluate the relationship between stathmin expression and clinical outcome in colorectal cancer (CRC). BACKGROUND Stathmin is a phosphoprotein involved in the regulation of microtubule dynamics and integration of intracellular signaling
Autor:
Kenichi Urakami, Takashi Sugino, Keiichi Fujiya, Takeshi Nagashima, Kenichi Nakamura, Keiichi Ohshima, Yasuto Akiyama, Yasuhiro Tsubosa, Ken Yamaguchi, Yuko Kitagawa, Masakuni Serizawa, Daisuke Aizawa, Masanori Terashima, Keiichi Hatakeyama
Publikováno v:
Gastric Cancer. 24:341-351
Resection for hepatic recurrence after gastrectomy in patients with gastric cancer may be curative; however, the prediction of hepatic recurrence remains intractable. Therefore, we aimed to explore predictive markers for hepatic recurrence in gastric
Autor:
Laura Lehtinen, Raija Ristamäki, Vanina D. Heuser, Annika Ålgars, Eva-Maria Birkman, Olli Carpén, Naziha Mansuri, Minnamaija Lintunen, Jari Sundström
Publikováno v:
Virchows Archiv
While host immune response is likely to be important for the prognosis of gastric cancer patients, detailed information on the T lymphocyte infiltration in different gastric cancer subtypes is lacking. Here, we studied the presence of CD3, CD8, and F
Autor:
Lei Fang, Shiqing Wang, Zhuoshi Li, Tao Guo, Qiang Xie, Wenzhi Liu, Fengzhou Li, Shilei Zhao, Chundong Gu
Publikováno v:
Human Cell. 33:1252-1263
The significance of the polypeptide N-acetyl-galactosaminyl transferase-3 (GalNAc-T3) and mucin 1 (MUC1) in solitary pulmonary adenocarcinoma (SPA) initially diagnosed as malignant solitary pulmonary nodule (≤ 3 cm), especially as a combined predic
Autor:
Hakan Alakus, Alexander Quaas, Reinhard Buettner, Christiane J. Bruns, Wolfgang Schröder, Max Krämer, Florian Gebauer, Heike Loeser, Philipp Lohneis, Martin Thelen, Hans A. Schlößer, Thomas Zander
Publikováno v:
Journal of Cancer Research and Clinical Oncology
Purpose Lymphocyte activation gene-3 (LAG3) is an immunosuppressive checkpoint molecule expressed on T cells. The frequency and distribution of LAG3 expression in oesophageal adenocarcinoma (EAC) is unknown. Aim of the study was the evaluation and di
BMI-1 promotes invasion and metastasis in endometrial adenocarcinoma and is a poor prognostic factor
Publikováno v:
Oncology Reports
Endometrial adenocarcinoma is one of the most common types of gynecological malignancies and its incidence and mortality rates are increasing. Due to tumor recurrence and metastasis, the overall five‑year survival rate of patients with endometrial
Autor:
Ki-Chul Hwang, Sang Woo Kim, Jung-Won Choi, Seongtae Jeong, Woon Yong Jung, Yong Chan Lee, Yu Jin Kim
Publikováno v:
International Journal of Medical Sciences
In our previous study, we identified three miRNAs (hsa-miR-421, hsa-miR-29b-1-5p, and hsa-miR-27b-5p) with two mRNAs (FBXO11 and CREBZF) that might play an important role in the development of gastric adenocarcinoma (GAC) from premalignant adenomas.
Autor:
Xiaoguang Yu, Zheng-Yuan Jiang, Wei Wang, Chi Liu, Xiulan Zheng, Rongjun Cui, Yujia Pan, Jialin Fan, Jiebing Tang, Jia-Hui Wan, Yu-Cui Lin
Publikováno v:
Cancer Medicine, Vol 8, Iss 14, Pp 6358-6369 (2019)
Cancer Medicine
Cancer Medicine
Background As an oncogene, long noncoding RNA metastasis‐associated lung adenocarcinoma transcript 1 (MALAT1) can promote tumor metastasis. Hyperexpression of MALAT1 has been observed in many malignant tumors, including hepatocellular carcinoma (HC