Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Anne Vekhoff"'
Autor:
Pierre Fenaux, Anne Vekhoff, A Sadoun, Arnaud Pigneux, L. Degos, N. Gratecos, Jean-Pierre Vilque, Xavier Thomas, T de Revel, Claude Gardin, Agnes Buzyn, P Naccache, Philippe Travade, Françoise Huguet, Nathalie Fegueux, Frédéric Maloisel, J.Y. Cahn, Christian Berthou, Christine Chomienne, Catherine Cordonnier, Oumedaly Reman, Agnès Guerci, P Kotoucek, Aspasia Stamatoullas, Hervé Dombret
Publikováno v:
Leukemia. 14:1006-1013
The purpose of this study was to assess the safety and efficacy of stem cell transplantation (SCT) mainly autologous SCT as consolidation therapy in APL patients who relapsed and achieved a second complete remission (CR2). Fifty adult patients with a
Autor:
Jean-Francois Lambert, Christine Chomienne, Laurent Degos, Bruno Cassinat, Bruno Quesnel, Nobert Vey, E. Deconinck, Sylvie Chevret, Stéphane de Botton, Xavier Thomas, Arnaud Pigneux, Anne Vekhoff, Thierry Lamy, Agnès Guerci-Bresler, Hervé Dombret, Emmanuel Raffoux, Bruno Lioure, Pierre Fenaux, Augustin Ferrant, Lionel Ades, Françoise Huguet
Publikováno v:
American journal of hematology. 88(7)
All-trans retinoic acid (ATRA) combined to anthracycline-based chemotherapy is the reference treatment of acute promyelocytic leukemia (APL). Whereas, in high-risk patients, cytarabine (AraC) is often considered useful in combination with anthracycli
Autor:
Jean-Yves Cahn, Françoise Huguet, Miguel A. Sanz, Norbert Ifrah, Stéphane de Botton, Thierry Lamy, Thomas Pabst, Edo Vellenga, Pierre Fenaux, Consuelo Rayon, Juan Bergua, Patrice Chevallier, Lionel Ades, Sandrine Meyer-Monard, Anne-Marie Stoppa, Hervé Dombret, Arnaud Pigneux, Pau Montesinos, Sylvie Chevret, Silvia Negri, Anne Vekhoff, Xavier Thomas, Dominique Bron, Agnès Guerci, Laurent Degos, Emmanuel Raffoux, Augustin Ferrant, Javier de la Serna, Ricardo Parody
Publikováno v:
Blood, 111(3), 1078-1084. AMER SOC HEMATOLOGY
All-trans retinoic acid (ATRA) plus anthracycline chemotherapy is the reference treatment of newly diagnosed acute promyelocytic leukemia (APL), whereas the role of cytosine arabinoside (AraC) remains disputed. We performed a joint analysis of patien
Autor:
Anne Vekhoff, Lionel Ades, Xavier Thomas, Anne-Marie Stoppa, Agnès Guerci, Laurent Degos, Eric Deconinck, Sandrine Meyer-Monard, Pierre Fenaux, Frédéric Maloisel, Emmanuel Raffoux, Hervé Dombret, Stéphane de Botton, Nathalie Fegueux, Christine Chomienne, Arnaud Pigneux, Augustin Ferrant, Thierry Lamy, Sylvie Chevret, Françoise Rigal-Huguet
Publikováno v:
Journal of Clinical Oncology
Journal of Clinical Oncology, American Society of Clinical Oncology, 2006, 24 (36), pp.5703-10. ⟨10.1200/JCO.2006.08.1596⟩
Journal of Clinical Oncology, American Society of Clinical Oncology, 2006, 24 (36), pp.5703-10. ⟨10.1200/JCO.2006.08.1596⟩
Purpose Several phase II studies have suggested that cytarabine (AraC) was not required in the treatment of newly diagnosed acute promyelocytic leukemia (APL) patients receiving all-trans-retinoic acid (ATRA), an anthracycline, and maintenance therap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::747a3d981583ca7a9c88c8bfc3210362
https://www.hal.inserm.fr/inserm-00473473
https://www.hal.inserm.fr/inserm-00473473
Autor:
Thierry Lamy, Agnès Guerci, Nathalie Fegueux, Anne Vekhoff, Miguel A. Sanz, Emmanuel Raffoux, Xavier Thomas, S. de Botton, J M Cayuela, F. Rigal-Huguet, Bruno Cassinat, Pierre Fenaux, A. Ferrand, Hervé Dombret, Sandrine Meyer-Monard, Sylvie Chevret, Arnaud Pigneux, Christine Chomienne, Anne-Marie Stoppa, C Callens
Publikováno v:
Leukemia. 19(7)
Internal tandem duplications (ITDs) of the FLT3 gene have been observed in about 35% of APL cases. If FLT3-ITD is associated with a worse outcome in patients with acute myeloid leukemia (AML) in general, its prognostic value in acute promyelocytic le
Autor:
C Mounier, Pierre Fenaux, I Lobe, Françoise Rigal-Huguet, Sylvie Chevret, L. Degos, Martin F. Fey, Augustin Ferrant, Miguel A. Sanz, Christine Chomienne, Bernard Desablens, Anne Vekhoff, Dominique Bordessoule
Publikováno v:
Leukemia. 17(8)
With improved treatment of acute promyelocytic leukemia (APL) by all trans retinoic acid ( ATRA) combined to anthracycline - aracytin chemotherapy (CT), a larger number of those patients may be at risk of late complications. Recently, the Rome group
Autor:
Pierre Fenaux, J F San Miguel, D. Cony Makhoul, J. de la Serna, Aspasia Stamatoulas, Anne Vekhoff, S. de Botton, Denis Caillot, Eulogio Conde, Martin F. Fey, Martine Gardembas, Hervé Dombret, Valérie Coiteux, Agnès Guerci, C. Gardin, Miguel A. Sanz, François Lefrère, Oumedaly Reman, L. Degos, Christine Chomienne, Sylvie Chevret
Publikováno v:
Leukemia. 17(2)
Treatment combining ATRA and chemotherapy (CT) has improved the outcome of APL patients, by comparison with CT alone. ATRA syndrome is a life-threatening complication of ATRA treatment whose prophylaxis remains somewhat controversial. In APL93 trial,
Autor:
Amine Belhabri, Xavier Thomas, Mauricette Michallet, Eric Archimbaud, Eric Wattel, Anne Vekhoff, Hervé Dombret, Nathalie Dhedin, Bruno Anglaret, Oumedaly Reman, Youcef Chelghoum, Denis Fiere
Publikováno v:
The hematology journal : the official journal of the European Haematology Association. 3(1)
Introduction: All trans retinoic acid has shown a remarkable eAectiveness in acute promyelocytic leukemia. These results have encouraged studies of treatment with ATRA in other acute myeloid leukemia subtypes. Patients and methods: In order to evalua
Autor:
Laurent Degos, Anne Vekhoff, J. Y. Cahn, C. Cordonnier, Christine Chomienne, Pierre Fenaux, Xavier Thomas, T. Cousin, N. Gratecos, Agnès Guerci, H. Dombret, Oumedaly Reman
Publikováno v:
Transplantation in Hematology and Oncology ISBN: 9783642640414
Because limited experience of autologous transplantation in acute promyelocytic leukemia (APL) is available, its place in this disease after all-trans retinoic acid (ATRA) plus chemotherapy is unknown. The purpose of this study was to assess the safe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8c9df1ac7aa4ab5ab03442410e54415f
https://doi.org/10.1007/978-3-642-59592-9_28
https://doi.org/10.1007/978-3-642-59592-9_28
Autor:
J. Y. Cahn, F. Maloisel, Sylvie Chevret, A. Guerci, J. de la Serna, T. Lamy, R. Chelo, Charikleia Kelaidi, Emmanuel Raffoux, Gaëlle H. Martin, Bruno Cassinat, T. Pabst, Lionel Ades, S. de Botton, X. Thomas, N. Fegueux, E. Deconinck, Anne Vekhoff, Claude Gardin, N. Ifrah, A. M. Stoppa, S. Meyer-Monard, Pierre Fenaux, P. Chevalier, A. Pigneux, D. Bron, M.A. Sanz, F. Rigal-Huguet, Hervé Dombret, A. Ferrant
Publikováno v:
Blood. 110:1845-1845
Background: APL is predominantly associated with low WBC counts. APL with very high WBC counts, i.e. >50 × 109/l, is rare, generally associated with severe coagulopathy and, before the ATRA era, was generally fatal due to early death or subsequent r