Zobrazeno 1 - 10
of 12
pro vyhledávání: 'Tuček, Jan'
Autor:
Stanislav Tuček, Jan Jakubík
Publikováno v:
Scopus-Elsevier
We have found earlier that the neuromuscular blocker alcuronium binds to cardiac muscarinic receptors simultaneously with their specific antagonist [3H]methyl-N-scopolamine ([3H]NMS) and allosterically increases their affinity to this ligand. Nothing
Publikováno v:
Molecular pharmacology. 52(1)
It is well known that allosteric modulators of muscarinic acetylcholine receptors can both diminish and increase the affinity of receptors for their antagonists. We investigated whether the allosteric modulators can also increase the affinity of rece
Autor:
Yves Dunant, Author
This book presents an up-to-date review concerning acetylcholine, a messenger substance which is produced transiently in practically all living organisms, from bacteria to human beings. High acetylcholine concentrations have been encountered in growi
Publikováno v:
Journal of neuroscience methods. 41(1)
A method is described for reversed-phase HPLC separation of acetylcholine and choline and of their homologues in tissue extracts or perfusion fluids, combined with postcolumn enzymatic derivatization and fluorometric quantification. The separation oc
Autor:
Jan R̀íčíný, Stanislav Tuček
Publikováno v:
Journal of Neurochemistry. 39:668-673
The effects of (-)-hydroxycitrate (OHC) and citrate on the concentration of acetylcoenzyme A (acetyl-CoA) and acetylcholine (ACh) in the tissue and on the release of ACh into the medium were investigated in experiments on slices of rat caudate nuclei
Autor:
Stanislav Tuček, Jan Říčný
Publikováno v:
Analytical biochemistry. 103(2)
The radioenzymatic method of acetyl coenzyme A (acetyl-CoA) determination in the brain devised by Shea and Aprison (1977, J. Neurochem. 28 , 51–58.) is based on the principle that tissue acetyl-CoA is incubated with [ 14 C]choline and choline acety
Autor:
Jakubik, Jan1 (AUTHOR) jan.jakubik@fgu.cas.cz, El-Fakahany, Esam E.2 (AUTHOR) jan.jakubik@fgu.cas.cz
Publikováno v:
Biomolecules (2218-273X). Feb2020, Vol. 10 Issue 2, p325. 1p.
Autor:
Alexander G. Karczmar
Even if the “weapons of mass destruction” (WMD) and, among them, stocks of organoph- phorus (OP) agents (also referred to as war gases and nerve gases) were not found in Iraq following the US-Iraq war, the relative ease with which these substance
Glutamate and GABA are the main information carrying neurotransmitters in the brain. Their action is modulated by a further series of small molecules called neuromodulators. The major neuromodulators in the brain are acetylcholine (both muscarinic an