Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Nicholas G. Gottardo"'
Autor:
Aniello Federico, Raelene Endersby, Marcel Kool, Meegan Howlett, Jacqueline Whitehouse, Nicholas G. Gottardo
Publikováno v:
Neuro-oncology Advances
Background Cranial radiation therapy is essential in treating many pediatric cancers, especially brain tumors; however, its use comes with the risk of developing second malignancies. Cranial radiation-induced gliomas (RIGs) are aggressive high-grade
Autor:
Elisa Carrasquedo Benito, Eric Bouffet, Tim Hassall, Murali Chintagumpala, Paul G. Fisher, Eric Sandler, Michelle Monje, Scott L Coven, Stewart Goldman, Lindsey Kilburn, Tabitha Cooney, Christopher L. Tinkle, Maryam Fouladi, Katie Black, Katherine E. Warren, Andrew Dodgshun, Kathleen Dorris, Ute Bartels, Hailey Bond, David S. Ziegler, Pratiti Bandopadhayay, Hetal Dholaria, Mariko DeWire-Schottmiller, Sarah Leary, Adam Lane, Blaise V. Jones, Jane E. Minturn, Yvan Samson, Raya Saab, Robert J. Greiner, Carl Koschmann, Anthony Asher, Nicholas G. Gottardo, Jordan R. Hansford, Sara Parkin, Brooklyn Chaney, James L. Leach, Lars M. Wagner, Roger J. Packer
Publikováno v:
Neuro-Oncology
There is no standard of care for cerebrospinal (CSF) diversion in children with diffuse intrinsic pontine glioma (DIPG), nor understanding of survival impact. We evaluated CSF diversion characteristics in children with DIPG to determine incidence, in
Autor:
G. Yancey Gillespie, Shago Mary, Richard Grundy, Maysa Al-Hussaini, Sarah Leary, Anne Bendel, Mei Lu, Ben Ho, Donna L. Johnston, Eloy Rivas, Nicolas André, Policlinico Vittorio Emanuele, Sandra Camelo-Piragua, Alvaro Lassaletta, Nisreen Amayiri, Nalin Gupta, Jordan R. Hansford, Christine Dahl, Sharon Low, Laura Amariglio, Peter B. Dirks, Palma Solano-Paez, Eric H. Raabe, Tannu Suwal, Mahjouba Boutarbouch, Kuo-Sheng Wu, Luca Massimi, Vicente Santa-Maria, Jesse Kresak, Jean M. Mulcahy Levy, Benjamin Ellezam, Michael D. Taylor, Ramya Ramanujachar, Jorgensen Mette, Somers Gino, Anna Maria Buccoliero, Dariusz Adamek, Cynthia Hawkins, Derek Hanson, Lucie Lafay-Cousin, Andres Morales, David Scharnhorst, Sara Khan, Eric Bouffet, Amy A Smith, Salma Al-Karmi, Maria Joao Gil da Costa, Hwang Eugene, Alyssa Reddy, Sumihito Nobusawa, Holly Lindsey, Jean Michaud, Andrew W. Walter, Lili-Naz Hazrati, Daniel Catchpoole, Tai-Tong Wong, Amar Gajjar, Yin Wang, Ashley Plant, Rubens Jeffery, Ahmet Muzaffer Demir, Hideo Nakamura, Derek Stephens, Andrew Dodgshun, Maryam Fouladi, Paul Wood, Christopher L. Moertel, Enrica Tan, Nicholas Gerber, David S. Ziegler, Nicholas G. Gottardo, Jason Fangusaro, Milena La Spina, Christelle Dufour, Annie Huang, Young-Shin Ra, Tarik Tihan, Nabil Kabbara, Franck Bourdeaut, Michal Yalon-Oren, Ute Bartels, Christopher Dunham
Publikováno v:
Neuro-Oncology
ETMR, an aggressive disease characterised by C19MC alterations, were previously categorised as various histologic diagnoses. The clinical spectrum and impact of conventional multi-modal therapy on this new WHO diagnostic category remains poorly under
Autor:
Tabitha Cooney, Lars M. Wagner, Kathleen Dorris, Carl Koschmann, Maryam Fouladi, Anthony Asher, Ayman El-Sheikh, Michelle Monje-Deisseroth, Pratiti Bandopadhayay, Roger J. Packer, Mariko DeWire-Schottmiller, Christine Fuller, Eric Bouffet, Sarah Leary, Kenneth J. Cohen, David S. Ziegler, Tim Hassall, Lindsay Kilburn, Cynthia Hawkins, James L. Leach, Katie Black, Yvan Samson, Karen Tsui, Hetal Dholaria, Paul G. Fisher, Jordan R. Hansford, Sylvia Cheng, Rachid Drissi, Blanca Diez, Adam Lane, Stewart Goldman, Blaise V. Jones, Sridharan Gururangan, Mercedes Garcia Lombardi, Scott L. Coven, Eric Sandler, Robert J. Greiner, Jane E. Minturn, Gustavo Sevlever, Margot A. Lazow, Brooklyn Chaney, Christopher L. Tinkle, Mohamed S. Zaghloul, Ute Bartels, Motasem El-Ayadi, Jie Ma, Nicholas G. Gottardo
Publikováno v:
Neuro-Oncology
INTRODUCTION The role of diagnostic biopsy in diffuse intrinsic pontine glioma (DIPG) remains in question. Distinguishing radiographically between DIPG and other pontine tumors with more favorable prognosis and different therapy is critically importa
Autor:
Pratiti Bandopadhayay, Yvan Samson, Maryam Fouladi, Katie Black, David S. Ziegler, Stewart Goldman, Mariko DeWire-Schottmiller, Kathleen Dorris, Lars M. Wagner, Sarah Leary, Adam Lane, Eric Sandler, Eric Bouffet, Murali Chintagumpala, Sylvia Cheng, Lucie Lafay-Cousin, Austin Schafer, Scott L Coven, Tim Hassall, Rachid Drissi, Sara Parkin, Lindsey Kilburn, Christopher L. Tinkle, Michelle Monje-Deisseroth, Jie Ma, Katherine E. Warren, Hetal Dholaria, Roger J. Packer, Paul D. Fisher, Andrew Dodgshun, Christine Fuller, Karen Tsui, Mohamed S. Zaghloul, Jordan R. Hansford, Sridharan Gururangan, Mercedes Garcia Lombardi, Brooklyn Chaney, Douglas Strother, Jane E. Minturn, Blaise V. Jones, Kenneth J. Cohen, James L. Leach, Ute Bartels, Motasem El-Ayadi, Raya Saab, Robert J. Greiner, David Gass, Nicholas G. Gottardo, Carl Koschmann
Publikováno v:
Neuro-Oncology
PURPOSE To review data from DIPG Registry patients recorded to have received a second course of radiation therapy (rRT). METHODS The International DIPG Registry was searched for patients with DIPG who were treated with a known dose of rRT. Doses of r
Autor:
Michael A. Grotzer, Marina Ryzhova, Kyle S. Smith, Olaf Witt, Ivo Buchhalter, Dominic Sturm, Paul A. Northcott, David T.W. Jones, Kayla V. Hamilton, Sonia Partap, Emilie Indersie, Daniel C. Bowers, Ruth G. Tatevossian, Anne Bendel, Laurence Brugières, Till Milde, Christelle Dufour, Stefan M. Pfister, Tobias Rausch, M Remke, Jan O. Korbel, Amy M. Smith, Tanvi Sharma, Sebastian M. Waszak, Giles W. Robinson, Stefan Rutkowski, Brent A. Orr, Natalie Jäger, Andrey Korshunov, Stéphanie Puget, Olivier Ayrault, Brandon J. Wainwright, Marcel Kool, Antoine Forget, Jennifer Hadley, Marija Kojic, Kim E. Nichols, Amar Gajjar, Damarys Loew, Peter Lichter, Garcia-Lopez Jesus, Kristian W. Pajtler, John R. Crawford, Nicholas G. Gottardo, David W. Ellison, Bérangère Lombard, Brian Gudenas, Murali Chintagumpala
Publikováno v:
Neuro-Oncology
BACKGROUND Our previous analysis of established cancer predisposition genes in medulloblastoma (MB) identified pathogenic germline variants in ~5% of all patients. Here, we extended our analysis to include all protein-coding genes. METHODS Case-contr
Autor:
Melissa J. Davis, Emily Girald, Brandon J. Wainwright, Amanda Millar, Christelle Adolphe, Emily Hassall, Mani Kuchibhotla, Matthew Singleton, Anne Bernard, Nicholas G. Gottardo, Laura A. Genovesi, Elissa Tolson, Caterina Brighi, Marija Kojic, Clara Andradas, Raelene Endersby, James M. Olson
Publikováno v:
Neuro-oncology Advances
Background Medulloblastoma (MB) is the most common malignant paediatric brain tumour and a leading cause of cancer-related mortality and morbidity. Existing treatment protocols are aggressive in nature resulting in significant neurological, intellect
Autor:
Sabine Mueller, Rishi S. Kotecha, Schuyler Stoller, Jie Huang, Alison Wray, Katja von Hoff, Olivia Wells, Jordan R. Hansford, Andrew Dodgshun, Amar Gajjar, Annie Huang, Eugene Hwang, Bryan K. Li, Raelene Endersby, Maryam Fouladi, Arzu Onar, Steven E. Schild, David R. Raleigh, Eric Bouffet, Sarah Leary, Pratiti Bandopadhayay, Nicholas G. Gottardo
Publikováno v:
Neuro-Oncology
Background Pineoblastoma (PB) is a rare embryonal brain tumour most often diagnosed in young children. To date, no clinical trials have been conducted specific to pediatric PB. Collaborative studies performed over the past 30 years have included PB i
Autor:
Hendrik Witt, David T.W. Jones, Nicolas U. Gerber, Jordan R. Hansford, Denise Obrecht, Chia Huan Ng, Kanika Bhatia, Rolf D. Kortmann, Olivia Wells, Molly Williams, Dong Anh Khuong Quang, Katja von Hoff, Elizabeth Algar, Brigitte Bison, Martin Benesch, Christine White, Vijay Ramaswamy, Stefan Rutkowski, Molly Buntine, Michael D. Taylor, Ulrich Schüller, Martin Mynarek, Kathryn M. Kinross, Nicholas G Gottardo, Kristian W. Pajtler, Monika Warmuth-Metz, Martin Campbell, Stefan M. Pfister, Michael J. Sullivan, Torsten Pietsch
Publikováno v:
Neuro-Oncology
AIM Advances in molecular classification of paediatric ependymoma have been pivotal in improving risk stratification and understanding of this disease. C11orf95-RELA fused supratentorial ependymoma (ST-EPN) have been reported to have a poor outcome,
Autor:
Jacqueline Whitehouse, Martin A. Ebert, Meegan Howlett, Brooke Strowger, Kale Somers, Andrew Mehnert, Hilary Hii, Nicholas G. Gottardo, Jessica Buck, Raelene Endersby
Publikováno v:
Neuro-Oncology
Treatment for medulloblastoma involves craniospinal irradiation which is associated with devastating late effects. Clinical trials that simply reduce radiotherapy dosage have resulted in inferior survival rates, whereas new chemo/radiotherapy combina