Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Maria Tsoli"'
Autor:
Richard J. Cohn, Maria Tsoli, David S. Ziegler, Mark J. Cowley, Paul G Ekert, Michelle Haber, Loretta Lau, Michael C. Cox, Vanessa Tyrell, Glenn M. Marshall
Genes encoding neurotrophin receptor kinases (TRK) have recently been implicated as an oncogenic driver in multiple tumor types including congenital fibrosarcoma, papillary thyroid cancer and adult glioblastoma. TRK fusions have been found in up to 4
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c44cd131060c0ec281f2beb32cb4c97
https://europepmc.org/articles/PMC6012581/
https://europepmc.org/articles/PMC6012581/
Autor:
Denise Yu, Laura D. Gamble, Michelle Haber, Laura Franshaw, Murray D. Norris, Swapna Joshi, Aaminah Khan, Maria Tsoli, David S. Ziegler, Mark R. Burns
Diffuse intrinsic pontine glioma (DIPG) is an aggressive paediatric brainstem tumour, with a median survival below 1 year. Polyamines, frequently upregulated in cancer, are small intracellular polycations that control key biological processes includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54828f6b94f8b58bfbe150db3fd31138
https://europepmc.org/articles/PMC6012726/
https://europepmc.org/articles/PMC6012726/
Autor:
Glenn M. Marshall, Jennifer A. Byrne, Maria Tsoli, Murray D. Norris, Siva Sivarajasingam, Laura Franshaw, David S. Ziegler
The rarity of childhood cancer, and high cure rates, mean only a limited number of novel therapies can be tested in patients with relapsed or refractory disease. Despite this, most novel therapeutic strategies fail in early phase trials. Of those tha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d598cf7b619c1ab5aba35c3c96eb081
https://europepmc.org/articles/PMC5475191/
https://europepmc.org/articles/PMC5475191/
Diffuse Intrinsic Pontine Glioma (DIPG) is the most aggressive form of malignant glioma to affect children. DIPG tumours cannot be surgically removed, do not respond to chemotherapy and are highly resistant to radiotherapy. Almost all children presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cfe650fec3d23a0f8452bbd87238c4af
https://europepmc.org/articles/PMC5474987/
https://europepmc.org/articles/PMC5474987/
Autor:
Phil Hogg, Han Shen, David S. Ziegler, Jie Liu, Pierre J. Dilda, Angel M. Carcaboso, Laura Franshaw, Arjanna Chintranjan, Maria Tsoli, Cecilia Chang
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9cbe783e89f090354007f45fe32e074
https://europepmc.org/articles/PMC4903393/
https://europepmc.org/articles/PMC4903393/
Autor:
Arjanna Chitranjan, Jie Liu, Anahid Ehteda, Eric Hau, Cecilia Chang, Santosh Valvi, Anne Kankean, David S. Ziegler, Maria Tsoli, Han Shen, Laura Franshaw
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21220db28d46198fa35393099e293893
https://europepmc.org/articles/PMC4903355/
https://europepmc.org/articles/PMC4903355/
Autor:
Cecilia Chang, Michelle Haber, Han Shen, Jie Liu, Anne Kankean, Sandy Simon, Maria Tsoli, David S. Ziegler, Andrei V. Gudkov, Arjanna Chitranjan, Anahid Ehteda
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4787ad1144e1498cbd3e0b6b2075568
https://europepmc.org/articles/PMC4903394/
https://europepmc.org/articles/PMC4903394/
Autor:
Nicole Yeung, Jie Liu, Santosh Valvi, Maria Tsoli, Han Shen, Laura Franshaw, Swapna Joshi, David S. Ziegler
Publikováno v:
Neuro-Oncology. 19:iv5-iv6
Diffuse Intrinsic Pontine Gliomas (DIPGs) are the most devastating of all brain tumours. They mostly affect young children and, as there are no effective treatments, almost all will die of their tumour within 12 months. We performed a high throughput
Publikováno v:
Neuro-Oncology. 19:iv5-iv5
Diffuse Intrinsic Pontine Glioma (DIPG) is the most aggressive of all childhood cancers and the leading cause of brain tumour-related death in children. There is no effective treatment for DIPG, and all patients die from this disease. Hitherto, radio
DIPG-09. TRX-E-009-1 IS A NOVEL AND A POTENT THERAPEUTIC AGENT FOR DIFFUSE INTRINSIC PONTINE GLIOMAS
Autor:
Anne Kankean, Arjanna Chitranjan, Eleanor Ager, Han Shen, Swapna Joshi, Anahid Ehteda, Maria Tsoli, Jie Liu, Laura Franshaw, Cecilia Chang, David S. Ziegler
Publikováno v:
Neuro-Oncology. 19:iv6-iv6
Diffuse Intrinsic Pontine Gliomas (DIPGs) are the most devastating of all brain tumours. They mostly affect young children and, as there are no effective treatments, almost all will succumb to the disease within 12 months. TRX-E-009-1 is a novel anti