Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Khalid M. El-Say"'
Publikováno v:
Pharmaceutics, Vol 13, Iss 739, p 739 (2021)
Pharmaceutics
Volume 13
Issue 5
Pharmaceutics
Volume 13
Issue 5
To avoid the first-pass metabolism of avanafil (AVA) and its altered absorption in the presence of food after oral administration, this study aimed to investigate the potential of TPGS-based mixed micelle (MM)-loaded film for transdermal delivery and
Autor:
Tahani S Basahih, Abdullah A Alamoudi, Nabil A. Alhakamy, Khalid M. El-Say, Osama A. A. Ahmed
Publikováno v:
Dose-Response, Vol 18 (2020)
Dose-Response
Dose-Response
Glimepiride (GMD) is a hypoglycemic agent that has variation in bioavailability for its unexpected absorption. Glimepiride was formulated in a buccal film loaded with a nanobased formulation to enhance its absorption via buccal mucosa. Nanostructured
Autor:
Khalid M. El-Say, Mahmoud A. Elfaky, Bader M Aljaeid, Usama A. Fahmy, Ohood A. Al-Shareef, Hibah M. Aldawsari
Publikováno v:
Journal of Drug Delivery Science and Technology. 46:7-13
Self-nanoemulsifying delivery systems (SNEDs) are one of the most important approaches for increasing the solubilization and absorption of a drug. This study aimed to develop a system using fluvastatin (FLV) in SNEDs with minimum globule size to enha
Autor:
Hossam S. El-Sawy, Tarek A. Ahmed, Khalid M. El-Say, Magid Abou-Gharbia, Reza Fassihi, Arwa H. Aljefri
Publikováno v:
International Journal of Pharmaceutics. 608:121057
To enhance the poor bioavailability and extensive liver metabolism of atorvastatin calcium (ATC), we have developed an oleic acid–reinforced PEGylated polymethacrylate (OLA–PEG–E-RLPO) transdermal film as a convenient and alternative delivery s
Publikováno v:
Pharmaceutics
Volume 11
Issue 1
Pharmaceutics, Vol 11, Iss 1, p 11 (2019)
Volume 11
Issue 1
Pharmaceutics, Vol 11, Iss 1, p 11 (2019)
Because of poor solubility and considerable metabolism, vardenafil (VRD) bioavailability is 15%. To overcome this obstacle, this study aimed to increase the solubility, hasten the onset of action, and mask the unpleasant taste of VRD utilizing &beta<
Publikováno v:
Journal of pharmaceutical sciences. 106(9)
Owing to limited solubility, vitamin K undergoes low bioavailability with large inter-individual variability after oral administration. This article aimed to prepare self-nanoemulsifying lyophilized tablets (SNELTs) for the flash oral transmucosal de
Publikováno v:
International Journal of Nanomedicine
Mutlaq M Al-Subaie,1 Khaled M Hosny,1,2 Khalid Mohamed El-Say,1,3 Tarek A Ahmed,1,3 Bader M Aljaeid1 1Department of Pharmaceutics and Industrial Pharmacy, Faculty of Pharmacy, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia; 2Department of