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pro vyhledávání: '"Ramin Sakhtemani"'
Publikováno v:
PLoS ONE, Vol 12, Iss 9, p e0185010 (2017)
PLoS ONE
PLoS ONE
Most B cell cancers overexpress the enzyme activation-induced deaminase at high levels and this enzyme converts cytosines in DNA to uracil. The constitutive expression of this enzyme in these cells greatly increases the uracil content of their genome