Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Patricia Sancho"'
Publikováno v:
World Journal of Stem Cells
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Digital.CSIC. Repositorio Institucional del CSIC
Zaguán: Repositorio Digital de la Universidad de Zaragoza
Universidad de Zaragoza
Zaguán. Repositorio Digital de la Universidad de Zaragoza
instname
Digital.CSIC. Repositorio Institucional del CSIC
©The Author(s) 2020.
[Background]:Cellular metabolism regulates stemness in health and disease. A reduced redox state is essential for self-renewal of normal and cancer stem cells (CSCs). However, while stem cells rely on glycolysis, different
[Background]:Cellular metabolism regulates stemness in health and disease. A reduced redox state is essential for self-renewal of normal and cancer stem cells (CSCs). However, while stem cells rely on glycolysis, different
Autor:
Sonia Alcalá, Laure Penin-Peyta, Juan A. Rubiolo, Petra Jagust, Beatriz de Luxán-Delgado, Laura Sánchez, Bruno Sainz, Beatriz Parejo-Alonso, Patricia Sancho, Alba Royo-García, Christopher Heeschen, Sarah Courtois
Publikováno v:
Cancers
Volume 13
Issue 4
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
Cancers, Vol 13, Iss 698, p 698 (2021)
Volume 13
Issue 4
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
Minerva. Repositorio Institucional de la Universidad de Santiago de Compostela
Minerva: Repositorio Institucional de la Universidad de Santiago de Compostela
Universidad de Santiago de Compostela (USC)
Cancers, Vol 13, Iss 698, p 698 (2021)
Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest tumors, partly due to its intrinsic aggressiveness, metastatic potential, and chemoresistance of the contained cancer stem cells (CSCs). Pancreatic CSCs strongly rely on mitochondrial me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d629a37dcd5db04bf64395ecfa5afd35
https://hdl.handle.net/10486/698922
https://hdl.handle.net/10486/698922
Autor:
Yu Wang, Fevzi Demircioglu, Kairbaan Hodivala-Dilke, Jane K. Sosabowski, Frances R. Balkwill, Christian Frezza, Louise E. Reynolds, Beatriz de Luxan Delgado, Jun Wang, Juliana Candido, Trevor A. Graham, Vinothini Rajeeve, Thomas J. Schall, Jesus Gomez-Escudero, Ana S. H. Costa, Julie Foster, Pedro R. Cutillas, Ann-Marie Baker, Patricia Sancho, Emma Newport, Marina Roy-Luzarraga, Penglie Zhang, Pedro Casado, James Campbell, Rajinder Singh
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
Nature Communications
Nature Communications
Emerging evidence suggests that cancer cell metabolism can be regulated by cancer-associated fibroblasts (CAFs), but the mechanisms are poorly defined. Here we show that CAFs regulate malignant cell metabolism through pathways under the control of FA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::add484c1fb3f0bca45d774eb13fbd4ba
https://www.repository.cam.ac.uk/handle/1810/303324
https://www.repository.cam.ac.uk/handle/1810/303324
Publikováno v:
British Journal of Cancer
Cancer cells adapt cellular metabolism to cope with their high proliferation rate. Instead of primarily using oxidative phosphorylation (OXPHOS), cancer cells use less efficient glycolysis for the production of ATP and building blocks (Warburg effect
Autor:
Marta Cañamero, Maria M. Azevedo, Bruno Sainz, Sonia Alcalá, Patrick C. Hermann, Mert Erkan, Michele Cioffi, Patricia Sancho, Marianthi Tatari, Christopher Heeschen, Manuel Hidalgo, Irene Miranda-Lorenzo, J. Kleeff, Elena Garcia, Gonzalo Gómez-López, Susana García-Silva, Yolanda Sanchez-Ripoll
Publikováno v:
Biblos-e Archivo. Repositorio Institucional de la UAM
instname
instname
This is the peer reviewed version of the following article: Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment. Gut 64.12 (2015): 1921-1935 and which has been published in final f
Publikováno v:
Journal of Visualized Experiments : JoVE
Pancreatic ductal adenocarcinoma (PDAC) contains a subset of exclusively tumorigenic cancer stem cells (CSCs) which have been shown to drive tumor initiation, metastasis and resistance to radio- and chemotherapy. Here we describe a specific methodolo
Autor:
Santos A. Susin, Hélène Merle-Béral, Patricia Sancho, Marlène Bras, Marika Sarfati, Gaël Roué, Josep E. Esquerda, Manuel Rubio, Victor J. Yuste, Clémence Virely, Sylvie Baudet, Laurent Chatre, Sandrine Barbier
Publikováno v:
Repositorio Abierto de la UdL
Universitad de Lleida
Recercat. Dipósit de la Recerca de Catalunya
instname
Universitad de Lleida
Recercat. Dipósit de la Recerca de Catalunya
instname
Background Programmed cell death has been traditionally related with caspase activation. However, it is now accepted that caspase-independent forms of programmed cell death also regulate cell death. In chronic lymphocytic leukemia, CD47 ligation indu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::831d4eee608c4c0d6a47c9f8f2e83fc9
https://hdl.handle.net/10459.1/49258
https://hdl.handle.net/10459.1/49258
Autor:
Mariano Barbacid, Luis Gandía, Paola Martinelli, Catarina R. Vieira, Patrick C. Hermann, Alexandra Aicher, Ricardo de Pascual, Francesc Madriles, Marta Cañamero, Patricia Sancho, Christopher Heeschen, Francisco X. Real, Carmen Guerra, Bruno Sainz, Patrick Michl, Martin Wagner, Thomas M. Gress
Publikováno v:
Gastroenterology
Background & Aims Although smoking is a leading risk factor for pancreatic ductal adenocarcinoma (PDAC), little is known about the mechanisms by which smoking promotes initiation or progression of PDAC. Methods We studied the effects of nicotine admi
Autor:
Christopher Heeschen, Enza Lonardo, Yolanda Sanchez-Ripoll, Sara Trabulo, Jorge Dorado, Manuel Hidalgo, Anamaria Balic, Patricia Sancho, Michele Cioffi
Publikováno v:
PLoS ONE
PLoS ONE; Vol 8
PLoS ONE, Vol 8, Iss 10, p e76518 (2013)
PLoS ONE; Vol 8
PLoS ONE, Vol 8, Iss 10, p e76518 (2013)
Pancreatic ductal adenocarcinomas contain a subset of exclusively tumorigenic cancer stem cells (CSCs), which are capable of repopulating the entire heterogeneous cancer cell populations and are highly resistant to standard chemotherapy. Here we demo
Autor:
Robert Eferl, Patricia Sancho, Wolfgang Mikulits, Eva Crosas-Molist, César Roncero, Isabel Fabregat, Conrado M. Fernández-Rodríguez, Fernando Pinedo, Jèssica Mainez, Heidemarie Huber
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45285 (2012)
PLoS ONE
PLoS ONE; Vol 7
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
PLoS ONE
PLoS ONE; Vol 7
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona
A role for the NADPH oxidases NOX1 and NOX2 in liver fibrosis has been proposed, but the implication of NOX4 is poorly understood yet. The aim of this work was to study the functional role of NOX4 in different cell populations implicated in liver fib