Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Pablo Helguera"'
Autor:
Anna Vazquez, Eric D. Hamlett, Sébastien Malinge, Yann Herault, Frances K. Wiseman, Bradley T. Christian, Laura del Hoyo Soriano, Patricia A Shaw, Floriana Costanzo, John D. Crispino, Eugenio Barone, Jean Maurice Delabar, Renata Bartesaghi, Alain D. Dekker, Juan Fortea Ormaechea, Véronique Brault, Marzia Perluigi, Peter Paul De Deyn, Mara Dierssen, Elizabeth M. C. Fisher, Tarik F. Haydar, Lisa M. Jacola, Marie-Claude Potier, Stephanie L. Sherman, Anita Bhattacharyya, Leonard J Abbeduto, William C. Mobley, Maria Florencia Iulita, Andre Strydom, Maria Carmona-Iragui, María Martínez de Lagrán, Jorge Busciglio, Pablo Helguera, Anna J. Esbensen
Publikováno v:
Molecular Syndromology
Molecular Syndromology, Karger, 2021, 12 (4), pp.202-218. ⟨10.1159/000514437⟩
Molecular Syndromology, 1-17. KARGER
STARTPAGE=1;ENDPAGE=17;ISSN=1661-8769;TITLE=Molecular Syndromology
Molecular syndromology, vol 12, iss 4
Mol Syndromol
Molecular syndromology
Molecular Syndromology, Karger, 2021, 12 (4), pp.202-218. ⟨10.1159/000514437⟩
Molecular Syndromology, 1-17. KARGER
STARTPAGE=1;ENDPAGE=17;ISSN=1661-8769;TITLE=Molecular Syndromology
Molecular syndromology, vol 12, iss 4
Mol Syndromol
Molecular syndromology
International audience; Research focused on Down syndrome has increased in the last several years to advance understanding of the consequences of trisomy 21 (T21) on molecular and cellular processes and, ultimately, on individuals with Down syndrome.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53c0ac5c585975417238d2ee740daa8a
https://hal.archives-ouvertes.fr/hal-03359724
https://hal.archives-ouvertes.fr/hal-03359724
Autor:
Pinar Coskun, Sergio A. Cannas, Emiliano Zamponi, Nahuel Zamponi, Pablo Helguera, Alfredo Lorenzo, Jorge Busciglio, Gonzalo Quassollo, Katheleen Gardiner, Gustavo Pigino, Dante R. Chialvo
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Zamponi, Emiliano; Zamponi, Nahuel; Coskun, Pinar; Quassollo, Gonzalo; Lorenzo, Alfredo; Cannas, Sergio A; et al.(2018). Nrf2 stabilization prevents critical oxidative damage in Down syndrome cells.. Aging Cell, 17(5), e12812. doi: 10.1111/acel.12812. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8m88h0wf
Aging Cell
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Zamponi, Emiliano; Zamponi, Nahuel; Coskun, Pinar; Quassollo, Gonzalo; Lorenzo, Alfredo; Cannas, Sergio A; et al.(2018). Nrf2 stabilization prevents critical oxidative damage in Down syndrome cells.. Aging Cell, 17(5), e12812. doi: 10.1111/acel.12812. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8m88h0wf
Aging Cell
Mounting evidence implicates chronic oxidative stress as a critical driver of the aging process. Down syndrome (DS) is characterized by a complex phenotype, including early senescence. DS cells display increased levels of reactive oxygen species (ROS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b894ecceb0cb89ba5e91dc15fc467058
Wiley Online Library
Wiley Online Library
Autor:
Yuyu Song, Hector Hugo Caicedo, Fiamma Buratti, Emiliano Zamponi, Lisa Jungbauer, Scott T. Brady, Mariano Bisbal, Gabriel Enrique Cataldi, Jiyan Ma, Alfredo Lorenzo, Pablo Helguera, Gerardo Morfini, Gustavo Pigino, Mary Jo LaDu
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188340 (2017)
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
PLoS ONE
Prion diseases include a number of progressive neuropathies involving conformational changes in cellular prion protein (PrPc) that may be fatal sporadic, familial or infectious. Pathological evidence indicated that neurons affected in prion diseases
Autor:
Pablo Helguera, Jose A. Rodriguez, Michael G. Hanna, Jaqueline Seiglie, Gustavo Helguera, Jorge Busciglio
Publikováno v:
Helguera, P; Seiglie, J; Rodriguez, J; Hanna, M; Helguera, G; & Busciglio, J. (2013). Adaptive Downregulation of Mitochondrial Function in Down Syndrome. CELL METABOLISM, 17(1), 132-140. doi: 10.1016/j.cmet.2012.12.005. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/77m6v7qp
Mitochondrial dysfunction and oxidative stress are common features of Down syndrome (DS). However, the underlying mechanisms are not known. We investigated the relationship between abnormal energy metabolism and oxidative stress with transcriptional
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b8d70af8a1b2926aa7fa819d718aab0
http://www.sciencedirect.com/science/article/pii/S1550413112004962#
http://www.sciencedirect.com/science/article/pii/S1550413112004962#