Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Neill, R Graff-Radford"'
Autor:
Sid E. O'Bryant, Tanis J. Ferman, Fan Zhang, James Hall, Otto Pedraza, Zbigniew K. Wszolek, Tori Como, David Julovich, Sravan Mattevada, Leigh A. Johnson, Melissa Edwards, Neill R. Graff‐Radford
Publikováno v:
Alzheimer’s & Dementia: Diagnosis, Assessment & Disease Monitoring, Vol 11, Iss 1, Pp 270-276 (2019)
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Alzheimer's & Dementia : Diagnosis, Assessment & Disease Monitoring
Introduction We sought to determine if a proteomic profile approach developed to detect Alzheimer's disease would distinguish patients with Lewy body disease from normal controls, and if it would distinguish dementia with Lewy bodies (DLB) from Parki
Autor:
Neill R. Graff-Radford, Amanda M. Liesinger, Owen A. Ross, Shunsuke Koga, Fadi S. Hanna Al-Shaikh, Kelly M. Hinkle, Rickey E. Carter, Adel Aziz, Melissa E. Murray, Nilufer Ertekin-Taner, McKenna K.F. Johnson, Sarah K. Dilello, Ranjan Duara, Dennis W. Dickson
Publikováno v:
Acta Neuropathologica
Women reportedly make up two-thirds of Alzheimer’s disease (AD) dementia sufferers. Many estimates regarding AD, however, are based on clinical series lacking autopsy confirmation. The Florida Autopsied Multi-Ethnic (FLAME) cohort was queried for A
Autor:
Nigel J. Cairns, David J. Stone, Tamas Revesz, Rita Guerreiro, Janice L. Holton, Jose Bras, Andrew J. Lees, Tanis J. Ferman, Afina W. Lemstra, Eliezer Masliah, Pentti J. Tienari, Pau Pastor, Ronald C. Petersen, Geidy E. Serrano, Celia Kun-Rodrigues, Elisabet Londos, Henrik Zetterberg, Dena G. Hernandez, John C. Morris, Tatiana Orme, Andrew B. Singleton, Owen A. Ross, Ekaterina Rogaeva, Thomas G. Beach, Karen Marder, Claire Troakes, Tammaryn Lashley, Kevin Morgan, Peter St George-Hyslop, Suzanne Lesage, Laura Parkkinen, Olaf Ansorge, Dennis W. Dickson, Glenda M. Halliday, John Q. Trojanowski, Liisa Myllykangas, Lorraine N. Clark, Isabel Santana, Neill R. Graff-Radford, Brad F. Boeve, Safa Al-Sarraj, Douglas Galasko, Minna Oinas, Vivianna M. Van Deerlin, Yaroslau Compta, John Hardy, Valentina Escott-Price, Lawrence S. Honig, Claire E. Shepherd, David M. A. Mann, Stuart Pickering-Brown, Lee Darwent
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-11 (2020)
Orme, T, Hernandez, D, Ross, O A, Kun-Rodrigues, C, Darwent, L, Shepherd, C E, Parkkinen, L, Ansorge, O, Clark, L, Honig, L S, Marder, K, Lemstra, A, Rogaeva, E, St George-Hyslop, P, Londos, E, Zetterberg, H, Morgan, K, Troakes, C, Al-Sarraj, S, Lashley, T, Holton, J, Compta, Y, Van Deerlin, V, Trojanowski, J Q, Serrano, G E, Beach, T G, Lesage, S, Galasko, D, Masliah, E, Santana, I, Pastor, P, Tienari, P J, Myllykangas, L, Oinas, M, Revesz, T, Lees, A, Boeve, B F, Petersen, R C, Ferman, T J, Escott-Price, V, Graff-Radford, N, Cairns, N J, Morris, J C, Pickering-Brown, S, Mann, D, Halliday, G, Stone, D J, Dickson, D W, Hardy, J, Singleton, A, Guerreiro, R & Bras, J 2020, ' Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies ', Acta Neuropathologica Communinications, vol. 8, no. 1, 5, pp. 5 . https://doi.org/10.1186/s40478-020-0879-z
Acta Neuropathologica Communications
Acta Neuropathologica Communinications, 8(1):5. BioMed Central
Universidad de Barcelona
Acta Neuropathologica Communications, Vol 8, Iss 1, Pp 1-11 (2020)
Orme, T, Hernandez, D, Ross, O A, Kun-Rodrigues, C, Darwent, L, Shepherd, C E, Parkkinen, L, Ansorge, O, Clark, L, Honig, L S, Marder, K, Lemstra, A, Rogaeva, E, St George-Hyslop, P, Londos, E, Zetterberg, H, Morgan, K, Troakes, C, Al-Sarraj, S, Lashley, T, Holton, J, Compta, Y, Van Deerlin, V, Trojanowski, J Q, Serrano, G E, Beach, T G, Lesage, S, Galasko, D, Masliah, E, Santana, I, Pastor, P, Tienari, P J, Myllykangas, L, Oinas, M, Revesz, T, Lees, A, Boeve, B F, Petersen, R C, Ferman, T J, Escott-Price, V, Graff-Radford, N, Cairns, N J, Morris, J C, Pickering-Brown, S, Mann, D, Halliday, G, Stone, D J, Dickson, D W, Hardy, J, Singleton, A, Guerreiro, R & Bras, J 2020, ' Analysis of neurodegenerative disease-causing genes in dementia with Lewy bodies ', Acta Neuropathologica Communinications, vol. 8, no. 1, 5, pp. 5 . https://doi.org/10.1186/s40478-020-0879-z
Acta Neuropathologica Communications
Acta Neuropathologica Communinications, 8(1):5. BioMed Central
Dementia with Lewy bodies (DLB) is a clinically heterogeneous disorder with a substantial burden on healthcare. Despite this, the genetic basis of the disorder is not well defined and its boundaries with other neurodegenerative diseases are unclear.
Publikováno v:
Mayo Clinic Proceedings. 92:978-994
Alzheimer disease (AD) was originally conceived as a rare disease that caused presenile dementia but has come to be understood as the most prevalent cause of dementia at any age worldwide. It has an extended preclinical phase characterized by sequent
Autor:
Marwan N. Sabbagh, James E. Galvin, Victoria S. Pelak, Sharon J. Sha, Katherine Amodeo, Charbel Moussa, Liana S. Rosenthal, Stephen N. Gomperts, Jennifer G. Goldman, Carol A. Manning, Kimiko Domoto-Reilly, Lawrence S. Honig, Daniel E. Huddleston, Mike Koehler, Neill R. Graff-Radford, Ian Richards, Kathleen L. Poston, Melissa J. Armstrong, Joseph F. Quinn, Douglas Galasko, Samantha K. Holden, Fernando Pagan, John E. Duda, Matthew J. Barrett, Brad F. Boeve, Angela Lunde, Douglas W. Scharre, Carol F. Lippa, Henry L. Paulson, James B. Leverenz, Irene Litvan, Tina Christie, Angela C. Taylor, Holly A. Shill, Todd Graham, Alexander Pantelyat, Irene H. Richard, David J. Irwin, Daniel I. Kaufer, Ian G. McKeith, Yasar Torres-Yaghi, Bethany Peterson, Chiadi U. Onyike, Andrew Siderowf, Karen Marder
Publikováno v:
Alzheimer's Research & Therapy
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-4 (2019)
Alzheimer's research & therapy, vol 11, iss 1
Peterson, Bethany; Armstrong, Melissa; Galasko, Douglas; Galvin, James E; Goldman, Jennifer; Irwin, David; et al.(2019). Lewy Body Dementia Association's Research Centers of Excellence Program: Inaugural Meeting Proceedings.. Alzheimer's research & therapy, 11(1), 23. doi: 10.1186/s13195-019-0476-1. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/1b22r11c
Alzheimer’s Research & Therapy, Vol 11, Iss 1, Pp 1-4 (2019)
Alzheimer's research & therapy, vol 11, iss 1
Peterson, Bethany; Armstrong, Melissa; Galasko, Douglas; Galvin, James E; Goldman, Jennifer; Irwin, David; et al.(2019). Lewy Body Dementia Association's Research Centers of Excellence Program: Inaugural Meeting Proceedings.. Alzheimer's research & therapy, 11(1), 23. doi: 10.1186/s13195-019-0476-1. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/1b22r11c
The first Lewy Body Dementia Association (LBDA) Research Centers of Excellence (RCOE) Investigator’s meeting was held on December 14, 2017, in New Orleans. The program was established to increase patient access to clinical experts on Lewy body deme
Autor:
Sonja W. Scholz, Pentti J. Tienari, Dena G. Hernandez, Elisabet Londos, Alberto Lleó, Imelda Barber, Jose Bras, Owen A. Ross, Tanis J. Ferman, Tatiana Orme, Juan C. Troncoso, Andrew B. Singleton, John D. Eicher, John Hardy, Karen Marder, Tammaryn Lashley, Douglas Galasko, Liisa Myllykangas, Ted M. Dawson, Eliezer Masliah, David M. A. Mann, Ekaterina Rogaeva, Stuart Pickering-Brown, Monica Diez-Fairen, Claire Troakes, Peter St George-Hyslop, Nigel J. Cairns, Dennis W. Dickson, Lee Darwent, Thomas G. Beach, David J. Stone, Olga Pletnikova, Glenda M. Halliday, Jordi Clarimón, John Q. Trojanowski, Anne Braae, Claire E. Shepherd, Pau Pastor, Geidy E. Serrano, Susana Carmona, Minna Oinas, Andrew J. Lees, Afina W. Lemstra, Miquel Aguilar, Laura Parkkinen, Rita Guerreiro, Estrella Morenas-Rodríguez, Janice L. Holton, Olaf Ansorge, Tamas Revesz, Vivianna M. Van Deerlin, Neill R. Graff-Radford, Safa Al-Sarraj, Kristelle Brown, Valentina Escott-Price, Suzanne Lesage, Lawrence S. Honig, Celia Kun-Rodrigues, John C. Morris, Ronald C. Petersen, Henrik Zetterberg, Kevin Morgan, Brad F. Boeve, Lorraine N. Clark, Isabel Santana, Yaroslau Compta, Liana S. Rosenthal, Michael G. Heckman
Publikováno v:
Kun-Rodrigues, C, Orme, T, Carmona, S, Hernandez, D G, Ross, O A, Eicher, J D, Shepherd, C, Parkkinen, L, Darwent, L, Heckman, M G, Scholz, S W, Troncoso, J C, Pletnikova, O, Dawson, T, Rosenthal, L, Ansorge, O, Clarimon, J, Lleo, A, Morenas-Rodriguez, E, Clark, L, Honig, L S, Marder, K, Lemstra, A, Rogaeva, E, St. George-Hyslop, P, Londos, E, Zetterberg, H, Barber, I, Braae, A, Brown, K, Morgan, K, Troakes, C, Al-Sarraj, S, Lashley, T, Holton, J, Compta, Y, van Deerlin, V, Serrano, G E, Beach, T G, Lesage, S, Galasko, D, Masliah, E, Santana, I, Pastor, P, Diez-Fairen, M, Aguilar, M, Tienari, P J, Myllykangas, L, Oinas, M, Revesz, T, Lees, A, Boeve, B F, Petersen, R C, Ferman, T J, Escott-Price, V, Graff-Radford, N, Cairns, N J, Morris, J C, Pickering-Brown, S, Mann, D, Halliday, G M, Hardy, J, Trojanowski, J Q, Dickson, D W, Singleton, A, Stone, D J, Guerreiro, R & Bras, J 2019, ' A comprehensive screening of copy number variability in dementia with Lewy bodies ', Neurobiology of Aging, vol. 75, pp. 223.e1-223.e10 . https://doi.org/10.1016/j.neurobiolaging.2018.10.019
Neurobiology of aging 75, 223.e1-223.e10 (2019). doi:10.1016/j.neurobiolaging.2018.10.019
Neurobiology of Aging, 75, 223.e1-223.e10. Elsevier Inc.
NEUROBIOLOGY OF AGING
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Neurobiology of aging 75, 223.e1-223.e10 (2019). doi:10.1016/j.neurobiolaging.2018.10.019
Neurobiology of Aging, 75, 223.e1-223.e10. Elsevier Inc.
NEUROBIOLOGY OF AGING
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
The role of genetic variability in dementia with Lewy bodies (DLB) is now indisputable; however, data regarding copy number variation (CNV) in this disease has been lacking. Here, we used whole-genome genotyping of 1454 DLB cases and 1525 controls to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fe78b5077a5e0a2df60bae68e7079cb
https://hdl.handle.net/10400.4/2247
https://hdl.handle.net/10400.4/2247
Autor:
Jiang, Shan, Wen, Natalie, Zeran, Li, Dube, Umber, Del Aguila, Jorge, Budde, John, Martinez, Rita, Hsu, Simon, Fernandez, Maria V, Cairns, Nigel J, Harari, Oscar, Cruchaga, Carlos, Karch, Celeste MRaffaele Ferrari, Dena, G Hernandez, Michael, A Nalls, Jonathan, D Rohrer, Adaikalavan, Ramasamy, John B, J Kwok, Carol, Dobson-Stone, William, S Brooks, Peter, R Schofield, Glenda, M Halliday, John, R Hodges, Olivier, Piguet, Lauren, Bartley, Elizabeth, Thompson, Eric, Haan, Isabel, Hernández, Agustín, Ruiz, Mercè, Boada, Barbara, Borroni, Alessandro, Padovani, Carlos, Cruchaga, Nigel, J Cairns, Luisa, Benussi, Giuliano, Binetti, Roberta, Ghidoni, Gianluigi, Forloni, Daniela, Galimberti, Chiara, Fenoglio, Maria, Serpente, Elio, Scarpini, Jordi, Clarimón, Alberto, Lleó, Rafael, Blesa, Maria Landqvist Waldö, Karin, Nilsson, Christer, Nilsson, Ian R, A Mackenzie, Ging-Yuek, R Hsiung, David M, A Mann, Jordan, Grafman, Christopher, M Morris, Johannes, Attems, Timothy, D Griffiths, Ian, G McKeith, Alan, J Thomas, Pietrini, P, Edward, D Huey, Eric, M Wassermann, Atik, Baborie, Evelyn, Jaros, Michael, C Tierney, Pau, Pastor, Cristina, Razquin, Sara, Ortega-Cubero, Elena, Alonso, Robert, Perneczky, Janine, Diehl-Schmid, Panagiotis, Alexopoulos, Alexander, Kurz, Rainero, Innocenzo, Rubino, Elisa, Lorenzo, Pinessi, Ekaterina, Rogaeva, Peter St George-Hyslop, Giacomina, Rossi, Fabrizio, Tagliavini, Giorgio, Giaccone, James, B Rowe, Johannes C, M Schlachetzki, James, Uphill, John, Collinge, Simon, Mead, Adrian, Danek, Vivianna, M Van Deerlin, Murray, Grossman, John, Q Trojanowski, Julie van der Zee, William, Deschamps, Tim Van Langenhove, Marc, Cruts, Christine Van Broeckhoven, Stefano, F Cappa, Isabelle Le Ber, Didier, Hannequin, Véronique, Golfier, Martine, Vercelletto, Alexis, Brice, Benedetta, Nacmias, Sandro, Sorbi, Silvia, Bagnoli, Irene, Piaceri, Jørgen, E Nielsen, Lena, E Hjermind, Matthias, Riemenschneider, Manuel, Mayhaus, Bernd, Ibach, Gilles, Gasparoni, Sabrina, Pichler, Wei, Gu, Martin, N Rossor, Nick, C Fox, Jason, D Warren, Maria Grazia Spillantini, Huw, R Morris, Patrizia, Rizzu, Peter, Heutink, Julie, S Snowden, Sara, Rollinson, Anna, Richardson, Alexander, Gerhard, Amalia, C Bruni, Raffaele, Maletta, Francesca, Frangipane, Chiara, Cupidi, Livia, Bernardi, Maria, Anfossi, Maura, Gallo, Maria Elena Conidi, Nicoletta, Smirne, Rosa, Rademakers, Matt, Baker, Dennis, W Dickson, Neill, R Graff-Radford, Ronald, C Petersen, David, Knopman, Keith, A Josephs, Bradley, F Boeve, Joseph, E Parisi, William, W Seeley, Bruce, L Miller, Anna, M Karydas, Howard, Rosen, John, C van Swieten, Elise G, P Dopper, Harro, Seelaar, Yolande A, L Pijnenburg, Philip, Scheltens, Giancarlo, Logroscino, Rosa, Capozzo, Valeria, Novelli, Annibale, A Puca, Massimo, Franceschi, Alfredo, Postiglione, Graziella, Milan, Paolo, Sorrentino, Mark, Kristiansen, Huei-Hsin, Chiang, Caroline, Graff, Florence, Pasquier, Adeline, Rollin, Vincent, Deramecourt, Florence, Lebert, Dimitrios, Kapogiannis, Luigi, Ferrucci, Stuart, Pickering-Brown, Andrew, B Singleton, John, Hardy, Parastoo, Momeni
Publikováno v:
Translational Psychiatry
Translational Psychiatry, Vol 8, Iss 1, Pp 1-16 (2018)
Translational Psychiatry, Vol 8, Iss 1, Pp 1-16 (2018)
Mutations in the microtubule-associated protein tau (MAPT) gene cause autosomal dominant frontotemporal lobar degeneration with tau inclusions (FTLD-tau). MAPT p.R406W carriers present clinically with progressive memory loss and neuropathologically w
Autor:
Rita Guerreiro, Jose Bras, Tanis J. Ferman, Stuart Pickering-Brown, Susana Carmona, Laura Parkkinen, Andrew B. Singleton, Glenda M. Halliday, Jordi Clarimón, Lee Darwent, Olaf Ansorge, Monica Diez-Fairen, Karen Marder, Geidy E. Serrano, David M. A. Mann, Thomas G. Beach, Michael G. Heckman, Andrew J. Lees, Miquel Aguilar, Liisa Myllykangas, Tatiana Orme, Henrik Zetterberg, Alberto Lleó, Lorraine N. Clark, Estrella Morenas-Rodriguez, Claire E. Shepherd, Ekaterina Rogaeva, Elisabet Londos, Douglas Galasko, Isabel Santana, Nadia Dehghani, Kevin Morgan, Eliezer Masliah, Imelda Barber, John D. Eicher, Ronald C. Petersen, Brad F. Boeve, John Hardy, Claire Troakes, Joao Luis Neto, Celia Kun-Rodrigues, Peter St George-Hyslop, Dennis W. Dickson, Janice L. Holton, Pentti J. Tienari, Minna Oinas, Olga Pletnikova, Afina W. Lemstra, John Q. Trojanowski, John C. Morris, Liana S. Rosenthal, Anne Braae, Dena G. Hernandez, Nigel J. Cairns, Pau Pastor, David J. Stone, Juan C. Troncoso, Ted M. Dawson, Owen A. Ross, Tammaryn Lashley, Tamas Revesz, Yaroslau Compta, Sonja W. Scholz, Neill R. Graff-Radford, Safa Al-Sarraj, Vivianna M. Van Deerlin, Kristelle Brown, Valentina Escott-Price, Suzanne Lesage, Lawrence S. Honig
Publikováno v:
Guerreiro, R, Escott-Price, V, Hernandez, D G, Kun-Rodrigues, C, Ross, O A, Orme, T, Neto, J L, Carmona, S, Dehghani, N, Eicher, J D, Shepherd, C, Parkkinen, L, Darwent, L, Heckman, M G, Scholz, S W, Troncoso, J C, Pletnikova, O, Dawson, T, Rosenthal, L, Ansorge, O, Clarimon, J, Lleo, A, Morenas-Rodriguez, E, Clark, L, Honig, L S, Marder, K, Lemstra, A, Rogaeva, E, St. George-Hyslop, P, Londos, E, Zetterberg, H, Barber, I, Braae, A, Brown, K, Morgan, K, Troakes, C, Al-Sarraj, S, Lashley, T, Holton, J, Compta, Y, van Deerlin, V, Serrano, G E, Beach, T G, Lesage, S, Galasko, D, Masliah, E, Santana, I, Pastor, P, Diez-Fairen, M, Aguilar, M, International Parkinson's Disease Genomics Consortium, Tienari, P J, Myllykangas, L, Ferman, T J, Graff-Radford, N R, Cairns, N J, Morris, J C, Pickering-Brown, S M, Mann, D M A, Halliday, G M, Hardy, J, Trojanowski, J, Dickson, D W, Singleton, A, Stone, D J & Bras, J 2019, ' Heritability and genetic variance of dementia with Lewy bodies ', Neurobiology of Disease, vol. 127, pp. 492-501 . https://doi.org/10.1016/j.nbd.2019.04.004
NEUROBIOLOGY OF DISEASE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Neurobiology of disease 127, 492-501 (2019). doi:10.1016/j.nbd.2019.04.004
Neurobiol Dis
Neurobiology of Disease, Vol 127, Iss, Pp 492-501 (2019)
Neurobiology of Disease, 127, 492-501. Academic Press Inc.
NEUROBIOLOGY OF DISEASE
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
instname
Neurobiology of disease 127, 492-501 (2019). doi:10.1016/j.nbd.2019.04.004
Neurobiol Dis
Neurobiology of Disease, Vol 127, Iss, Pp 492-501 (2019)
Neurobiology of Disease, 127, 492-501. Academic Press Inc.
Recent large-scale genetic studies have allowed for the first glimpse of the effects of common genetic variability in dementia with Lewy bodies (DLB), identifying risk variants with appreciable effect sizes. However, it is currently well established
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91ddf72792282ac6688e9cd408cbfdd7
Autor:
Neill R. Graff-Radford, Na Zhao, Owen A. Ross, Zbigniew K. Wszolek, Richard J. Caselli, Joshua Knight, Guojun Bu, Nancy N. Diehl, Cynthia Linares, Olivia N. Attrebi, Melissa E. Murray, Mitsuru Shinohara, Chia Chen Liu, Dennis W. Dickson, John D. Fryer, Rosa Rademakers, Yuka A. Martens, Monica Sanchez-Contreras, Michael G. Heckman, Alexandra J. Van Ingelgom, Leonard Petrucelli, Shunsuke Koga, Aishe Kurti
Publikováno v:
Nature Communications
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature communications
BASE-Bielefeld Academic Search Engine
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Nature communications
BASE-Bielefeld Academic Search Engine
Apolipoprotein E (APOE) ε4 allele is the strongest genetic risk factor for late-onset Alzheimer’s disease mainly by modulating amyloid-β pathology. APOE ε4 is also shown to exacerbate neurodegeneration and neuroinflammation in a tau transgenic m
Autor:
Neill R. Graff-Radford, Sarah Lincoln, Gamze Balci Camsari, Imelda Barber, Julia E. Crook, Qurat ul Ain Khan, Li Ma, Kevin Morgan, Steven G. Younkin, Minerva M. Carrasquillo, Dennis W. Dickson, Gina Bisceglio, Melissa E. Murray, Bradley F. Boeve, Nilufer Ertekin-Taner, Thuy Nguyen
Publikováno v:
Neurobiology of Aging. 37:38-44
Posterior cortical atrophy (PCA) is an understudied visual impairment syndrome most often due to “posterior Alzheimer’s disease (AD)” pathology. Case studies detected mutations in PSEN1, PSEN2, GRN, MAPT and PRNP in subjects with clinical PCA.