Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Amanda B. Muir"'
Publikováno v:
Clinical and Experimental Gastroenterology. 12:391-399
Eosinophilic esophagitis (EoE) is a disorder which affects all ages, from infancy through adulthood. It typically affects atopic individuals (Table 1) and is a chronic allergic disorder, with foods ubiquitous in the diet being the most described trig
Autor:
Manabu Muto, Masataka Shimonosono, Takaaki Arigami, Amanda B. Muir, Masaki Mori, Takashi Kijima, Yuta Kasagi, Shinya Ohashi, Andres J. Klein-Szanto, Prasanna M. Chandramouleeswaran, Narayan G. Avadhani, Itaru Omoto, Shoji Natsugoe, Gregory G. Ginsberg, Seiji Naganuma, Veronique Giroux, Varun Sahu, Yoshiaki Shinden, Osamu Kikuchi, Devraj Basu, J. Alan Diehl, Yasuto Uchikado, Koji Tanaka, Yoshiaki Kita, Yuichiro Doki, Adam J. Bass, Ken Sasaki, Hiroshi Nakagawa, Anil K. Rustgi, Kelly A. Whelan, Takeo Hara
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 73-91 (2019)
Cellular and Molecular Gastroenterology and Hepatology, Vol 7, Iss 1, Pp 73-91 (2019)
Background & Aims Oropharyngeal and esophageal squamous cell carcinomas, especially the latter, are a lethal disease, featuring intratumoral cancer cell heterogeneity and therapy resistance. To facilitate cancer therapy in personalized medicine, thre
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 4, Pp 461-478 (2018)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
The stratified squamous epithelium of the esophagus shows a proliferative basal layer of keratinocytes that undergo terminal differentiation in overlying suprabasal layers. Esophageal pathologies, including eosinophilic esophagitis, gastroesophageal
Autor:
Marc E. Rothenberg, Gary W. Falk, Joshua B. Wechsler, Amanda B. Muir, Glenn T. Furuta, Evan S. Dellon, Jonathan M. Spergel, Paul Menard-Katcher, Elizabeth T. Jensen, Seema S. Aceves
Eosinophilic colitis (EC) is a rare disorder characterized by eosinophilic inflammation of the colon causing diarrhea, bloody stool, nausea, constipation and abdominal pain. The Consortium for Eosinophilic Gastrointestinal Disease Research sought to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef2fc4b6fad64feb604d60688ef2d3cd
https://doi.org/10.1101/414557
https://doi.org/10.1101/414557
Autor:
Calies Menard-Katcher, Nirmala Gonsalves, Christina L Carpenter, Jonathan Kuhl, Gary W. Falk, Glenn T. Furuta, Marc E. Rothenberg, Jonathan Gross, Adam Z. Magier, Tokunbo Ashorobi, Robert D. Pesek, Faria N. Ahmed, Patricia C. Fulkerson, Ankur Gupta, Amanda B. Muir, Craig C. Reed, Evan S. Dellon, Maureen DeMarshall, Jeffrey P. Krischer, Jonathan M. Spergel, Sandeep K. Gupta
Financial Support and AcknowledgementsSupport for this project was provided through a research training grant as part of the Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) (U54 AI117804). CEGIR is part of the Rare Disease Cli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5db36f556494f34aab4492916e00a981
https://doi.org/10.1101/413583
https://doi.org/10.1101/413583
Autor:
Bridget Godwin, Chris Liacouras, Vijay Mehta, Joshua Eisenberg, Atu Agawu, Terri Brown-Whitehorn, Melanie A. Ruffner, Ritu Verma, Antonella Cianferoni, Jonathan M. Spergel, Amanda B. Muir
Publikováno v:
Frontiers in Pediatrics
Frontiers in Pediatrics, Vol 6 (2018)
Frontiers in Pediatrics, Vol 6 (2018)
Background: Eosinophilic esophagitis is a chronic, immune-mediated disease characterized by symptoms of esophageal dysfunction and ≥15 eosinophils/high-powered field (eos/hpf). Proton pump inhibitor responsive esophageal eosinophilia (1) is an enti
Autor:
Medha Sharma, Veronique Giroux, Alain Benitez, Kathryn E. Hamilton, Anil K. Rustgi, Joshua Wang, Kelly A. Whelan, Andres J. Klein-Szanto, Jonathan M. Spergel, Hiroshi Nakagawa, Gary W. Falk, Prasanna M. Chandramouleeswaran, John W. Tobias, Amanda B. Muir, Koji Tanaka, Maureen DeMarshall, Yuta Kasagi
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 333-352 (2018)
Cellular and Molecular Gastroenterology and Hepatology, Vol 5, Iss 3, Pp 333-352 (2018)
Background & Aims Aberrations in the esophageal proliferation-differentiation gradient are histologic hallmarks in eosinophilic esophagitis (EoE) and gastroesophageal reflux disease. A reliable protocol to grow 3-dimensional (3D) esophageal organoids
Autor:
Alain Benitez, Benjamin J. Wilkins, Kara K. Dods, Jamie Merves, Jonathan M. Spergel, Jennifer H. Yearley, Yuliana Noah, Anna J. Lee, Mei-Lun Wang, Amanda B. Muir, Prasanna M. Chandramouleeswaran, Rene De Waal Malefyt, Fiona Gambanga, Sarit Toltzis, Hiroshi Nakagawa, Dawen Shen
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150968 (2016)
PLoS ONE
PLoS ONE
Eosinophilic esophagitis (EoE) is a chronic Th2 and food antigen-mediated disease characterized by esophageal eosinophilic infiltration. Thymic stromal lymphopoetin (TSLP), an epithelial derived cytokine which bridges innate and Th2-type adaptive imm
Autor:
Glenn T. Furuta, Seema S. Aceves, Shaobo Guan, Lisa M. Fahey, Alain Benitez, Patrick M. A. Sleiman, Amanda B. Muir, Chris A. Liacouras, Jonathan M. Spergel, Prasanna M. Chandramouleeswaran, Hakon Hakonarson, Mei-Lun Wang, Antonella Cianferoni
Publikováno v:
Clinical and Translational Gastroenterology
Objectives TSLP has been shown to be associated with eosinophilic esophagitis (EoE). Specifically, children with EoE often have the nucleotides AA or AG instead of GG at the single nucleotide polymorphism position RS3806932. Presently, the phenotypic
Autor:
Kara K. Dods, Prasanna M. Chandramouleeswaran, Eduardo Ruchelli, Alain Benitez, Hiroshi Nakagawa, Amanda B. Muir, Jamie Merves, Mei-Lun Wang, Jonathan M. Spergel, Isha Mehta, Diana M. Lim, Anna J. Lee
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0114831 (2015)
PLoS ONE
PLoS ONE
Eosinophilic Esophagitis (EoE) is a chronic allergic disorder, whose pathobiology is incompletely understood. Histamine-producing cells including mast cells and basophils have been implicated in EoE. However, very little is currently known about the