Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Abecasis, Goncalo"'
Autor:
Hu, Yao, Stilp, Adrienne M, McHugh, Caitlin P, Rao, Shuquan, Jain, Deepti, Zheng, Xiuwen, Lane, John, Méric de Bellefon, Sébastian, Raffield, Laura M, Chen, Ming-Huei, Yanek, Lisa R, Wheeler, Marsha, Yao, Yao, Ren, Chunyan, Broome, Jai, Moon, Jee-Young, de Vries, Paul S, Hobbs, Brian D, Sun, Quan, Surendran, Praveen, Brody, Jennifer A, Blackwell, Thomas W, Choquet, Hélène, Ryan, Kathleen, Duggirala, Ravindranath, Heard-Costa, Nancy, Wang, Zhe, Chami, Nathalie, Preuss, Michael H, Min, Nancy, Ekunwe, Lynette, Lange, Leslie A, Cushman, Mary, Faraday, Nauder, Curran, Joanne E, Almasy, Laura, Kundu, Kousik, Smith, Albert V, Gabriel, Stacey, Rotter, Jerome I, Fornage, Myriam, Lloyd-Jones, Donald M, Vasan, Ramachandran S, Smith, Nicholas L, North, Kari E, Boerwinkle, Eric, Becker, Lewis C, Lewis, Joshua P, Abecasis, Goncalo R, Hou, Lifang, O'Connell, Jeffrey R, Morrison, Alanna C, Beaty, Terri H, Kaplan, Robert, Correa, Adolfo, Blangero, John, Jorgenson, Eric, Psaty, Bruce M, Kooperberg, Charles, Walton, Russell T, Kleinstiver, Benjamin P, Tang, Hua, Loos, Ruth JF, Soranzo, Nicole, Butterworth, Adam S, Nickerson, Debbie, Rich, Stephen S, Mitchell, Braxton D, Johnson, Andrew D, Auer, Paul L, Li, Yun, Mathias, Rasika A, Lettre, Guillaume, Pankratz, Nathan, Laurie, Cathy C, Laurie, Cecelia A, Bauer, Daniel E, Conomos, Matthew P, Reiner, Alexander P, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium
Publikováno v:
American journal of human genetics, vol 108, iss 5
Whole-genome sequencing (WGS), a powerful tool for detecting novel coding and non-coding disease-causing variants, has largely been applied to clinical diagnosis of inherited disorders. Here we leveraged WGS data in up to 62,653 ethnically diverse pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::445eb02b1c412ec0c77798d591b7420a
https://escholarship.org/uc/item/24j6v92r
https://escholarship.org/uc/item/24j6v92r
Autor:
Ferreira, Manuel A R, Vonk, Judith M., Baurecht, Hansjörg, Marenholz, Ingo, Tian, Chao, Hoffman, Joshua D., Helmer, Quinta, Tillander, Annika, Ullemar, Vilhelmina, Lu, Yi, Grosche, Sarah, Ruschendorf, Franz, Granell, Raquel, Brumpton, Ben Michael, Fritsche, Lars, Bhatta, Laxmi, Gabrielsen, Maiken Elvestad, Nielsen, Jonas Bille, Zhou, Wei, Hveem, Kristian, Langhammer, Arnulf, Holmen, Oddgeir, Løset, Mari, Abecasis, Goncalo, Willer, Cristen J., Emami, Nima C., Cavazos, Taylor B., Witte, John S., Szwajda, Agnieszka, 23andMe Research Team,, collaborators of SHARE study,, Hinds, David A., Hubner, Norbert, Weidinger, Stephan, Magnusson, Patrik KE, Jorgenson, Eric, Karlsson, Robert, Paternoster, Lavinia, Boomsma, Dorret I., Almqvist, Catarina, Lee, Young-Ae, Koppelman, Gerard H., Esparza-Gordillo, Jorge, Hummel, Oliver, Hottenga, Jouke-Jan, Willemsen, Gonneke, Rodríguez, Elke, Hotze, Melanie, Franke, Andre, Matheson, Melanie C., Dharmage, Shyamali Chandrika, Arnold, Andreas, Homuth, Georg, Schmidt, Carsten O, Thompson, Philip J., Martin, Nicholas G, Duffy, David L., Novak, Natalija, Schulz, Holger, Karrasch, Stefan, Gieger, Christian, Strauch, Konstantin, Melles, Ronald B
Publikováno v:
Ferreira, M A R, Granell, R, Brumpton, B M, Paternoster, L & al., E 2020, ' Age-of-onset information helps identify 76 genetic variants associated with allergic disease ', PLoS Genetics . https://doi.org/10.1371/journal.pgen.1008725
PLoS Genetics
PLoS Genetics, Vol 16, Iss 6, p e1008725 (2020)
PLoS genetics, vol 16, iss 6
PLoS Genetics, 16(6):e1008725, 1-30. Public Library of Science
Ferreira, M A R, Helmer, Q, Boomsma, D I, Koppelman, G H, 23Andme Research Team & collaborators of the SHARE study 2020, ' Age-of-onset information helps identify 76 genetic variants associated with allergic disease ', PLoS Genetics, vol. 16, no. 6, e1008725, pp. 1-30 . https://doi.org/10.1371/journal.pgen.1008725
PLoS genetics, 16(6):e1008725. PUBLIC LIBRARY SCIENCE
PLoS Genetics
PLoS Genetics, Vol 16, Iss 6, p e1008725 (2020)
PLoS genetics, vol 16, iss 6
PLoS Genetics, 16(6):e1008725, 1-30. Public Library of Science
Ferreira, M A R, Helmer, Q, Boomsma, D I, Koppelman, G H, 23Andme Research Team & collaborators of the SHARE study 2020, ' Age-of-onset information helps identify 76 genetic variants associated with allergic disease ', PLoS Genetics, vol. 16, no. 6, e1008725, pp. 1-30 . https://doi.org/10.1371/journal.pgen.1008725
PLoS genetics, 16(6):e1008725. PUBLIC LIBRARY SCIENCE
Risk factors that contribute to inter-individual differences in the age-of-onset of allergic diseases are poorly understood. The aim of this study was to identify genetic risk variants associated with the age at which symptoms of allergic disease fir
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef083f37bdedb51ecd1abbf93f78c33e
https://research-information.bris.ac.uk/ws/files/246941687/untitled.pdf
https://research-information.bris.ac.uk/ws/files/246941687/untitled.pdf
Autor:
Justice, Anne E, Karaderi, Tugce, Highland, Heather M, Young, Kristin L, Graff, Mariaelisa, Lu, Yingchang, Turcot, Valérie, Auer, Paul L, Fine, Rebecca S, Guo, Xiuqing, Schurmann, Claudia, Lempradl, Adelheid, Marouli, Eirini, Mahajan, Anubha, Winkler, Thomas W, Locke, Adam E, Medina-Gomez, Carolina, Esko, Tõnu, Vedantam, Sailaja, Giri, Ayush, Lo, Ken Sin, Alfred, Tamuno, Mudgal, Poorva, Ng, Maggie CY, Heard-Costa, Nancy L, Feitosa, Mary F, Manning, Alisa K, Willems, Sara M, Sivapalaratnam, Suthesh, Abecasis, Goncalo, Alam, Dewan S, Allison, Matthew, Amouyel, Philippe, Arzumanyan, Zorayr, Balkau, Beverley, Bastarache, Lisa, Bergmann, Sven, Bielak, Lawrence F, Blüher, Matthias, Boehnke, Michael, Boeing, Heiner, Boerwinkle, Eric, Böger, Carsten A, Bork-Jensen, Jette, Bottinger, Erwin P, Bowden, Donald W, Brandslund, Ivan, Broer, Linda, Burt, Amber A, Butterworth, Adam S, Caulfield, Mark J, Cesana, Giancarlo, Chambers, John C, Chasman, Daniel I, Chen, Yii-Der Ida, Chowdhury, Rajiv, Christensen, Cramer, Chu, Audrey Y, Collins, Francis S, Cook, James P, Cox, Amanda J, Crosslin, David S, Danesh, John, de Bakker, Paul IW, Denus, Simon de, Mutsert, Renée de, Dedoussis, George, Demerath, Ellen W, Dennis, Joe G, Denny, Josh C, Di Angelantonio, Emanuele, Dörr, Marcus, Drenos, Fotios, Dubé, Marie-Pierre, Dunning, Alison M, Easton, Douglas F, Elliott, Paul, Evangelou, Evangelos, Farmaki, Aliki-Eleni, Feng, Shuang, Ferrannini, Ele, Ferrieres, Jean, Florez, Jose C, Fornage, Myriam, Fox, Caroline S, Franks, Paul W, Friedrich, Nele, Gan, Wei, Gandin, Ilaria, Gasparini, Paolo, Giedraitis, Vilmantas, Girotto, Giorgia, Gorski, Mathias, Grallert, Harald, Grarup, Niels, Grove, Megan L, Gustafsson, Stefan, Haessler, Jeff, Hansen, Torben, Hattersley, Andrew T
Publikováno v:
Nature genetics, vol 51, iss 3
Body-fat distribution is a risk factor for adverse cardiovascular health consequences. We analyzed the association of body-fat distribution, assessed by waist-to-hip ratio adjusted for body mass index, with 228,985 predicted coding and splice site va
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::44e9320cc018881e9ec908bf4c8015fe
https://escholarship.org/uc/item/1fv3j0h9
https://escholarship.org/uc/item/1fv3j0h9
Autor:
Marouli, Eirini, Graff, Mariaelisa, Medina-Gomez, Carolina, Lo, Ken Sin, Wood, Andrew R, Kjaer, Troels R, Fine, Rebecca S, Lu, Yingchang, Schurmann, Claudia, Highland, Heather M, Rueger, Sina, Thorleifsson, Gudmar, Justice, Anne E, Lamparter, David, Stirrups, Kathleen E, Turcot, Valerie, Young, Kristin L, Winkler, Thomas W, Esko, Tonu, Karaderi, Tugce, Locke, Adam E, Masca, Nicholas GD, Ng, Maggie CY, Mudgal, Poorva, Rivas, Manuel A, Vedantam, Sailaja, Mahajan, Anubha, Guo, Xiuqing, Abecasis, Goncalo, Aben, Katja K, Adair, Linda S, Alam, Dewan S, Albrecht, Eva, Allin, Kristine H, Allison, Matthew, Amouyel, Philippe, Appel, Emil V, Arveiler, Dominique, Asselbergs, Folkert W, Auer, Paul L, Balkau, Beverley, Banas, Bernhard, Bang, Lia E, Benn, Marianne, Bergmann, Sven, Bielak, Lawrence F, Blueher, Matthias, Boeing, Heiner, Boerwinkle, Eric, Boeger, Carsten A, Bonnycastle, Lori L, Bork-Jensen, Jette, Bots, Michiel L, Bottinger, Erwin P, Bowden, Donald W, Brandslund, Ivan, Breen, Gerome, Brilliant, Murray H, Broer, Linda, Burt, Amber A, Butterworth, Adam S, Carey, David J, Caulfield, Mark J, Chambers, John C, Chasman, Daniel I, Chen, Yii-Der Ida, Chowdhury, Rajiv, Christensen, Cramer, Chu, Audrey Y, Cocca, Massimiliano, Collins, Francis S, Cook, James P, Corley, Janie, Galbany, Jordi Corominas, Cox, Amanda J, Cuellar-Partida, Gabriel, Danesh, John, Davies, Gail, de Bakker, Paul IW, de Borst, Gert J, de Denus, Simon, de Groot, Mark CH, de Mutsert, Renee, Deary, Ian J, Dedoussis, George, Demerath, Ellen W, den Hollander, Anneke I, Dennis, Joe G, Di Angelantonio, Emanuele, Drenos, Fotios, Du, Mengmeng, Dunning, Alison M, Easton, Douglas F, Ebeling, Tapani, Edwards, Todd L, Ellinor, Patrick T, Elliott, Paul, Evangelou, Evangelos, Farmaki, Aliki-Eleni, Faul, Jessica D, Feitosa, Mary F, Feng, Shuang, Ferrannini, Ele, Ferrario, Marco M, Ferrieres, Jean, Florez, Jose C, Ford, Ian, Fornage, Myriam, Franks, Paul W, Frikke-Schmidt, Ruth, Galesloot, Tessel E, Gan, Wei, Gandin, Ilaria, Gasparini, Paolo, Giedraitis, Vilmantas, Giri, Ayush, Girotto, Giorgia, Gordon, Scott D, Gordon-Larsen, Penny, Gorski, Mathias, Grarup, Niels, Grove, Megan L, Gudnason, Vilmundur, Gustafsson, Stefan, Hansen, Torben, Harris, Kathleen Mullan, Harris, Tamara B, Hattersley, Andrew T, Hayward, Caroline, He, Liang, Heid, Iris M, Heikkila, Kauko, Helgeland, Oyvind, Hernesniemi, Jussi, Hewitt, Alex W, Hocking, Lynne J, Hollensted, Mette, Holmen, Oddgeir L, Hovingh, G Kees, Howson, Joanna MM, Hoyng, Carel B, Huang, Paul L, Hveem, Kristian, Ikram, M Arfan, Ingelsson, Erik, Jackson, Anne U, Jansson, Jan-Hakan, Jarvik, Gail P, Jensen, Gorm B, Jhun, Min A, Jia, Yucheng, Jiang, Xuejuan, Johansson, Stefan, Jorgensen, Marit E, Jorgensen, Torben, Jousilahti, Pekka, Jukema, J Wouter, Kahali, Bratati, Kahn, Rene S, Kahonen, Mika, Kamstrup, Pia R, Kanoni, Stavroula, Kaprio, Jaakko, Karaleftheri, Maria, Kardia, Sharon LR, Karpe, Fredrik, Kee, Frank, Keeman, Renske, Kiemeney, Lambertus A, Kitajima, Hidetoshi, Kluivers, Kirsten B, Kocher, Thomas, Komulainen, Pirjo, Kontto, Jukka, Kooner, Jaspal S, Kooperberg, Charles, Kovacs, Peter, Kriebel, Jennifer, Kuivaniemi, Helena, Kury, Sebastien, Kuusisto, Johanna, La Bianca, Martina, Laakso, Markku, Lakka, Timo A, Lange, Ethan M, Lange, Leslie A, Langefeld, Carl D, Langenberg, Claudia, Larson, Eric B, Lee, I-Te, Lehtimaki, Terho, Lewis, Cora E, Li, Huaixing, Li, Jin, Li-Gao, Ruifang, Lin, Honghuang, Lin, Li-An, Lin, Xu, Lind, Lars, Lindstrom, Jaana, Linneberg, Allan, Liu, Yeheng, Liu, Yongmei, Lophatananon, Artitaya, Luan, Jian'an, Lubitz, Steven A, Lyytikainen, Leo-Pekka, Mackey, David A, Madden, Pamela AF, Manning, Alisa K, Mannisto, Satu, Marenne, Gaelle, Marten, Jonathan, Martin, Nicholas G, Mazul, Angela L, Meidtner, Karina, Metspalu, Andres, Mitchell, Paul, Mohlke, Karen L, Mook-Kanamori, Dennis O, Morgan, Anna, Morris, Andrew D, Morris, Andrew P, Mueller-Nurasyid, Martina, Munroe, Patricia B, Nalls, Mike A, Nauck, Matthias, Nelson, Christopher P, Neville, Matt, Nielsen, Sune F, Nikus, Kjell, Njolstad, Pal R, Nordestgaard, Borge G, Ntalla, Ioanna, O'Connel, Jeffrey R, Oksa, Heikki, Loohuis, Loes M Olde, Ophoff, Roel A, Owen, Katharine R, Packard, Chris J, Padmanabhan, Sandosh, Palmer, Colin NA, Pasterkamp, Gerard, Patel, Aniruddh P, Pattie, Alison, Pedersen, Oluf, Peissig, Peggy L, Peloso, Gina M, Pennell, Craig E, Perola, Markus, Perry, James A, Perry, John RB, Person, Thomas N, Pirie, Ailith, Polasek, Ozren, Posthuma, Danielle, Raitakari, Olli T, Rasheed, Asif, Rauramaa, Rainer, Reilly, Dermot F, Reiner, Alex P, Renstrom, Frida, Ridker, Paul M, Rioux, John D, Robertson, Neil, Robino, Antonietta, Rolandsson, Olov, Rudan, Igor, Ruth, Katherine S, Saleheen, Danish, Salomaa, Veikko, Samani, Nilesh J, Sandow, Kevin, Sapkota, Yadav, Sattar, Naveed, Schmidt, Marjanka K, Schreiner, Pamela J, Schulze, Matthias B, Scott, Robert A, Segura-Lepe, Marcelo P, Shah, Svati, Sim, Xueling, Sivapalaratnam, Suthesh, Small, Kerrin S, Smith, Albert Vernon, Smith, Jennifer A, Southam, Lorraine, Spector, Timothy D, Speliotes, Elizabeth K, Starr, John M, Steinthorsdottir, Valgerdur, Stringham, Heather M, Stumvoll, Michael, Surendran, Praveen, 't Hart, Leen M, Tansey, Katherine E, Tardif, Jean-Claude, Taylor, Kent D, Teumer, Alexander, Thompson, Deborah J, Thorsteinsdottir, Unnur, Thuesen, Betina H, Toenjes, Anke, Tromp, Gerard, Trompet, Stella, Tsafantakis, Emmanouil, Tuomilehto, Jaakko, Tybjaerg-Hansen, Anne, Tyrer, Jonathan P, Uher, Rudolf, Uitterlinden, Andre G, Ulivi, Sheila, van der Laan, Sander W, Van Der Leij, Andries R, van Duijn, Cornelia M, van Schoor, Natasja M, van Setten, Jessica, Varbo, Anette, Varga, Tibor V, Varma, Rohit, Edwards, Digna R Velez, Vermeulen, Sita H, Vestergaard, Henrik, Vitart, Veronique, Vogt, Thomas F, Vozzi, Diego, Walker, Mark, Wang, Feijie, Wang, Carol A, Wang, Shuai, Wang, Yiqin, Wareham, Nicholas J, Warren, Helen R, Wessel, Jennifer, Willems, Sara M, Wilson, James G, Witte, Daniel R, Woods, Michael O, Wu, Ying, Yaghootkar, Hanieh, Yao, Jie, Yao, Pang, Yerges-Armstrong, Laura M, Young, Robin, Zeggini, Eleftheria, Zhan, Xiaowei, Zhang, Weihua, Zhao, Jing Hua, Zhao, Wei, Zheng, He, Zhou, Wei, Rotter, Jerome I, Boehnke, Michael, Kathiresan, Sekar, McCarthy, Mark I, Willer, Cristen J, Stefansson, Kari, Borecki, Ingrid B, Liu, Dajiang J, North, Kari E, Heard-Costa, Nancy L, Pers, Tune H, Lindgren, Cecilia M, Oxvig, Claus, Kutalik, Zoltan, Rivadeneira, Fernando, Loos, Ruth JF, Frayling, Timothy M, Hirschhorn, Joel N, Deloukas, Panos, Lettre, Guillaume, Consortium, EPIC-InterAct, Consortium, EPIC-CVD, Consortium, CHD Exome, Consortium, ExomeBP, Consortium, T2D-Genes, Consortium, GoT2D Genes, Consortium, Global Lipids Genetics, Consortium, ReproGen, Investigators, MAGIC
Publikováno v:
Nature, 542, 186-190
Marouli, E, Graff, M, Medina-Gomez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Li, J, Posthuma, D, van Schoor, N M & EPIC-InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Marouli, E, Graff, M, Medina-Gomez, C, Lo, K S, Wood, A R, Kjær, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G R, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M A, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boeing, H, Boerwinkle, E, Jørgensen, T & EPIC-InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Marouli, E, Graff, M, Medina-Gomez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boeing, H, Boerwinkle, E, Posthuma, D & EPIC-InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
NATURE
Nature, 542(7640), 186-190. Nature Publishing Group
Nature 542, 186-190 (2017)
Nature
Nature, vol 542, iss 7640
Marouli, E, Graff, M, Medina-Gómez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G R, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M A, Amouyel, P, Appel, E V R, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Brandslund, I, Christensen, C, Hansen, T, Jensen, G B, Jørgensen, M E & EPIC-InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Marouli, E, Graff, M, Medina-Gómez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G R, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M A, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S M, Bielak, L F, Blüher, M, Boeing, H, Boerwinkle, E, Oxvig, C & EPIC InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Marouli, E, Graff, M, Medina-gomez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boeing, H, Boerwinkle, E, Böger, C A, Bonnycastle, L L, Bork-jensen, J, Bots, M L, Bottinger, E P, Bowden, D W, Brandslund, I, Breen, G, Brilliant, M H, Broer, L, Burt, A A, Butterworth, A S, Carey, D J, Caulfield, M J, Chambers, J C, Chasman, D I, Chen, Y I, Chowdhury, R, Christensen, C, Chu, A Y, Cocca, M, Collins, F S, Cook, J P, Corley, J, Galbany, J C, Cox, A J, Cuellar-partida, G, Danesh, J, Davies, G, De Bakker, P I W, De Borst, G J, De Denus, S, De Groot, M C H, De Mutsert, R, Deary, I J, Dedoussis, G, Demerath, E W, Den Hollander, A I, Dennis, J G, Di Angelantonio, E, Drenos, F, Du, M, Dunning, A M, Easton, D F, Ebeling, T, Edwards, T L, Ellinor, P T, Elliott, P, Evangelou, E, Farmaki, A, Faul, J D, Feitosa, M F, Feng, S, Ferrannini, E, Ferrario, M M, Ferrieres, J, Florez, J C, Ford, I, Fornage, M, Franks, P W, Frikke-schmidt, R, Galesloot, T E, Gan, W, Gandin, I, Gasparini, P, Giedraitis, V, Giri, A, Girotto, G, Gordon, S D, Gordon-larsen, P, Gorski, M, Grarup, N, Grove, M L, Gudnason, V, Gustafsson, S, Hansen, T, Harris, K M, Harris, T B, Hattersley, A T, Hayward, C, He, L, Heid, I M, Heikkilä, K, Helgeland, Ø, Hernesniemi, J, Hewitt, A W, Hocking, L J, Hollensted, M, Holmen, O L, Hovingh, G K, Howson, J M M, Hoyng, C B, Huang, P L, Hveem, K, Ikram, M A, Ingelsson, E, Jackson, A U, Jansson, J, Jarvik, G P, Jensen, G B, Jhun, M A, Jia, Y, Jiang, X, Johansson, S, Jørgensen, M E, Jørgensen, T, Jousilahti, P, Jukema, J W, Kahali, B, Kahn, R S, Kähönen, M, Kamstrup, P R, Kanoni, S, Kaprio, J, Karaleftheri, M, Kardia, S L R, Karpe, F, Kee, F, Keeman, R, Kiemeney, L A, Kitajima, H, Kluivers, K B, Kocher, T, Komulainen, P, Kontto, J, Kooner, J S, Kooperberg, C, Kovacs, P, Kriebel, J, Kuivaniemi, H, Küry, S, Kuusisto, J, La Bianca, M, Laakso, M, Lakka, T A, Lange, E M, Lange, L A, Langefeld, C D, Langenberg, C, Larson, E B, Lee, I, Lehtimäki, T, Lewis, C E, Li, H, Li, J, Li-gao, R, Lin, H, Lin, L, Lin, X, Lind, L, Lindström, J, Linneberg, A, Liu, Y, Liu, Y, Lophatananon, A, Luan, J, Lubitz, S A, Lyytikäinen, L, Mackey, D A, Madden, P A F, Manning, A K, Männistö, S, Marenne, G, Marten, J, Martin, N G, Mazul, A L, Meidtner, K, Metspalu, A, Mitchell, P, Mohlke, K L, Mook-kanamori, D O, Morgan, A, Morris, A D, Morris, A P, Müller-nurasyid, M, Munroe, P B, Nalls, M A, Nauck, M, Nelson, C P, Neville, M, Nielsen, S F, Nikus, K, Njølstad, P R, Nordestgaard, B G, Ntalla, I, O'connel, J R, Oksa, H, Loohuis, L M O, Ophoff, R A, Owen, K R, Packard, C J, Padmanabhan, S, Palmer, C N A, Pasterkamp, G, Patel, A P, Pattie, A, Pedersen, O, Peissig, P L, Peloso, G M, Pennell, C E, Perola, M, Perry, J A, Perry, J R B, Person, T N, Pirie, A, Polasek, O, Posthuma, D, Raitakari, O T, Rasheed, A, Rauramaa, R, Reilly, D F, Reiner, A P, Renström, F, Ridker, P M, Rioux, J D, Robertson, N, Robino, A, Rolandsson, O, Rudan, I, Ruth, K S, Saleheen, D, Salomaa, V, Samani, N J, Sandow, K, Sapkota, Y, Sattar, N, Schmidt, M K, Schreiner, P J, Schulze, M B, Scott, R A, Segura-lepe, M P, Shah, S, Sim, X, Sivapalaratnam, S, Small, K S, Smith, A V, Smith, J A, Southam, L, Spector, T D, Speliotes, E K, Starr, J M, Steinthorsdottir, V, Stringham, H M, Stumvoll, M, Surendran, P, ‘t Hart, L M, Tansey, K E, Tardif, J, Taylor, K D, Teumer, A, Thompson, D J, Thorsteinsdottir, U, Thuesen, B H, Tönjes, A, Tromp, G, Trompet, S, Tsafantakis, E, Tuomilehto, J, Tybjaerg-hansen, A, Tyrer, J P, Uher, R, Uitterlinden, A G, Ulivi, S, Van Der Laan, S W, Van Der Leij, A R, Van Duijn, C M, Van Schoor, N M, Van Setten, J, Varbo, A, Varga, T V, Varma, R, Edwards, D R V, Vermeulen, S H, Vestergaard, H, Vitart, V, Vogt, T F, Vozzi, D, Walker, M, Wang, F, Wang, C A, Wang, S, Wang, Y, Wareham, N J, Warren, H R, Wessel, J, Willems, S M, Wilson, J G, Witte, D R, Woods, M O, Wu, Y, Yaghootkar, H, Yao, J, Yao, P, Yerges-armstrong, L M, Young, R, Zeggini, E, Zhan, X, Zhang, W, Zhao, J H, Zhao, W, Zhao, W, Zheng, H, Zhou, W, Rotter, J I, Boehnke, M, Kathiresan, S, Mccarthy, M I, Willer, C J, Stefansson, K, Borecki, I B, Liu, D J, North, K E, Heard-costa, N L, Pers, T H, Lindgren, C M, Oxvig, C, Kutalik, Z, Rivadeneira, F, Loos, R J F, Frayling, T M, Hirschhorn, J N, Deloukas, P & Lettre, G 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Nature, 542(7640), 186-190
Marouli, E, Graff, M, Medina-Gomez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boeing, H, Boerwinkle, E, Lophatananon, A & EPIC-InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Nature, 542, 7640, pp. 186-190
Nature, 542(7640), 186. Nature Research
Nature, vol. 542, no. 7640, pp. 186-190
Marouli, E; Graff, M; Medina-Gomez, C; Lo, KS; Wood, AR; Kjaer, TR; et al.(2017). Rare and low-frequency coding variants alter human adult height. Nature, 542(7640), 186-190. doi: 10.1038/nature21039. UCLA: Retrieved from: http://www.escholarship.org/uc/item/1sq5r8fb
Nature, 542, 186. Nature Publishing Group
Marouli, E, Graff, M, Medina-Gomez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Li, J, Posthuma, D, van Schoor, N M & EPIC-InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Marouli, E, Graff, M, Medina-Gomez, C, Lo, K S, Wood, A R, Kjær, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G R, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M A, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boeing, H, Boerwinkle, E, Jørgensen, T & EPIC-InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Marouli, E, Graff, M, Medina-Gomez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boeing, H, Boerwinkle, E, Posthuma, D & EPIC-InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
NATURE
Nature, 542(7640), 186-190. Nature Publishing Group
Nature 542, 186-190 (2017)
Nature
Nature, vol 542, iss 7640
Marouli, E, Graff, M, Medina-Gómez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G R, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M A, Amouyel, P, Appel, E V R, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Brandslund, I, Christensen, C, Hansen, T, Jensen, G B, Jørgensen, M E & EPIC-InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Marouli, E, Graff, M, Medina-Gómez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G R, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M A, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S M, Bielak, L F, Blüher, M, Boeing, H, Boerwinkle, E, Oxvig, C & EPIC InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Marouli, E, Graff, M, Medina-gomez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boeing, H, Boerwinkle, E, Böger, C A, Bonnycastle, L L, Bork-jensen, J, Bots, M L, Bottinger, E P, Bowden, D W, Brandslund, I, Breen, G, Brilliant, M H, Broer, L, Burt, A A, Butterworth, A S, Carey, D J, Caulfield, M J, Chambers, J C, Chasman, D I, Chen, Y I, Chowdhury, R, Christensen, C, Chu, A Y, Cocca, M, Collins, F S, Cook, J P, Corley, J, Galbany, J C, Cox, A J, Cuellar-partida, G, Danesh, J, Davies, G, De Bakker, P I W, De Borst, G J, De Denus, S, De Groot, M C H, De Mutsert, R, Deary, I J, Dedoussis, G, Demerath, E W, Den Hollander, A I, Dennis, J G, Di Angelantonio, E, Drenos, F, Du, M, Dunning, A M, Easton, D F, Ebeling, T, Edwards, T L, Ellinor, P T, Elliott, P, Evangelou, E, Farmaki, A, Faul, J D, Feitosa, M F, Feng, S, Ferrannini, E, Ferrario, M M, Ferrieres, J, Florez, J C, Ford, I, Fornage, M, Franks, P W, Frikke-schmidt, R, Galesloot, T E, Gan, W, Gandin, I, Gasparini, P, Giedraitis, V, Giri, A, Girotto, G, Gordon, S D, Gordon-larsen, P, Gorski, M, Grarup, N, Grove, M L, Gudnason, V, Gustafsson, S, Hansen, T, Harris, K M, Harris, T B, Hattersley, A T, Hayward, C, He, L, Heid, I M, Heikkilä, K, Helgeland, Ø, Hernesniemi, J, Hewitt, A W, Hocking, L J, Hollensted, M, Holmen, O L, Hovingh, G K, Howson, J M M, Hoyng, C B, Huang, P L, Hveem, K, Ikram, M A, Ingelsson, E, Jackson, A U, Jansson, J, Jarvik, G P, Jensen, G B, Jhun, M A, Jia, Y, Jiang, X, Johansson, S, Jørgensen, M E, Jørgensen, T, Jousilahti, P, Jukema, J W, Kahali, B, Kahn, R S, Kähönen, M, Kamstrup, P R, Kanoni, S, Kaprio, J, Karaleftheri, M, Kardia, S L R, Karpe, F, Kee, F, Keeman, R, Kiemeney, L A, Kitajima, H, Kluivers, K B, Kocher, T, Komulainen, P, Kontto, J, Kooner, J S, Kooperberg, C, Kovacs, P, Kriebel, J, Kuivaniemi, H, Küry, S, Kuusisto, J, La Bianca, M, Laakso, M, Lakka, T A, Lange, E M, Lange, L A, Langefeld, C D, Langenberg, C, Larson, E B, Lee, I, Lehtimäki, T, Lewis, C E, Li, H, Li, J, Li-gao, R, Lin, H, Lin, L, Lin, X, Lind, L, Lindström, J, Linneberg, A, Liu, Y, Liu, Y, Lophatananon, A, Luan, J, Lubitz, S A, Lyytikäinen, L, Mackey, D A, Madden, P A F, Manning, A K, Männistö, S, Marenne, G, Marten, J, Martin, N G, Mazul, A L, Meidtner, K, Metspalu, A, Mitchell, P, Mohlke, K L, Mook-kanamori, D O, Morgan, A, Morris, A D, Morris, A P, Müller-nurasyid, M, Munroe, P B, Nalls, M A, Nauck, M, Nelson, C P, Neville, M, Nielsen, S F, Nikus, K, Njølstad, P R, Nordestgaard, B G, Ntalla, I, O'connel, J R, Oksa, H, Loohuis, L M O, Ophoff, R A, Owen, K R, Packard, C J, Padmanabhan, S, Palmer, C N A, Pasterkamp, G, Patel, A P, Pattie, A, Pedersen, O, Peissig, P L, Peloso, G M, Pennell, C E, Perola, M, Perry, J A, Perry, J R B, Person, T N, Pirie, A, Polasek, O, Posthuma, D, Raitakari, O T, Rasheed, A, Rauramaa, R, Reilly, D F, Reiner, A P, Renström, F, Ridker, P M, Rioux, J D, Robertson, N, Robino, A, Rolandsson, O, Rudan, I, Ruth, K S, Saleheen, D, Salomaa, V, Samani, N J, Sandow, K, Sapkota, Y, Sattar, N, Schmidt, M K, Schreiner, P J, Schulze, M B, Scott, R A, Segura-lepe, M P, Shah, S, Sim, X, Sivapalaratnam, S, Small, K S, Smith, A V, Smith, J A, Southam, L, Spector, T D, Speliotes, E K, Starr, J M, Steinthorsdottir, V, Stringham, H M, Stumvoll, M, Surendran, P, ‘t Hart, L M, Tansey, K E, Tardif, J, Taylor, K D, Teumer, A, Thompson, D J, Thorsteinsdottir, U, Thuesen, B H, Tönjes, A, Tromp, G, Trompet, S, Tsafantakis, E, Tuomilehto, J, Tybjaerg-hansen, A, Tyrer, J P, Uher, R, Uitterlinden, A G, Ulivi, S, Van Der Laan, S W, Van Der Leij, A R, Van Duijn, C M, Van Schoor, N M, Van Setten, J, Varbo, A, Varga, T V, Varma, R, Edwards, D R V, Vermeulen, S H, Vestergaard, H, Vitart, V, Vogt, T F, Vozzi, D, Walker, M, Wang, F, Wang, C A, Wang, S, Wang, Y, Wareham, N J, Warren, H R, Wessel, J, Willems, S M, Wilson, J G, Witte, D R, Woods, M O, Wu, Y, Yaghootkar, H, Yao, J, Yao, P, Yerges-armstrong, L M, Young, R, Zeggini, E, Zhan, X, Zhang, W, Zhao, J H, Zhao, W, Zhao, W, Zheng, H, Zhou, W, Rotter, J I, Boehnke, M, Kathiresan, S, Mccarthy, M I, Willer, C J, Stefansson, K, Borecki, I B, Liu, D J, North, K E, Heard-costa, N L, Pers, T H, Lindgren, C M, Oxvig, C, Kutalik, Z, Rivadeneira, F, Loos, R J F, Frayling, T M, Hirschhorn, J N, Deloukas, P & Lettre, G 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Nature, 542(7640), 186-190
Marouli, E, Graff, M, Medina-Gomez, C, Lo, K S, Wood, A R, Kjaer, T R, Fine, R S, Lu, Y, Schurmann, C, Highland, H M, Rüeger, S, Thorleifsson, G, Justice, A E, Lamparter, D, Stirrups, K E, Turcot, V, Young, K L, Winkler, T W, Esko, T, Karaderi, T, Locke, A E, Masca, N G D, Ng, M C Y, Mudgal, P, Rivas, M A, Vedantam, S, Mahajan, A, Guo, X, Abecasis, G, Aben, K K, Adair, L S, Alam, D S, Albrecht, E, Allin, K H, Allison, M, Amouyel, P, Appel, E V, Arveiler, D, Asselbergs, F W, Auer, P L, Balkau, B, Banas, B, Bang, L E, Benn, M, Bergmann, S, Bielak, L F, Blüher, M, Boeing, H, Boerwinkle, E, Lophatananon, A & EPIC-InterAct Consortium 2017, ' Rare and low-frequency coding variants alter human adult height ', Nature, vol. 542, no. 7640, pp. 186-190 . https://doi.org/10.1038/nature21039
Nature, 542, 7640, pp. 186-190
Nature, 542(7640), 186. Nature Research
Nature, vol. 542, no. 7640, pp. 186-190
Marouli, E; Graff, M; Medina-Gomez, C; Lo, KS; Wood, AR; Kjaer, TR; et al.(2017). Rare and low-frequency coding variants alter human adult height. Nature, 542(7640), 186-190. doi: 10.1038/nature21039. UCLA: Retrieved from: http://www.escholarship.org/uc/item/1sq5r8fb
Nature, 542, 186. Nature Publishing Group
Contains fulltext : 169801.pdf (Publisher’s version ) (Closed access) Height is a highly heritable, classic polygenic trait with approximately 700 common associated variants identified through genome-wide association studies so far. Here, we report
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https://doi.org/10.1038/nature21039
https://doi.org/10.1038/nature21039
Autor:
Savage, Jeanne E, Jansen, Philip R, Stringer, Sven, Watanabe, Kyoko, Bryois, Julien, de Leeuw, Christiaan A, Nagel, Mats, Awasthi, Swapnil, Barr, Peter B, Coleman, Jonathan RI, Grasby, Katrina L, Hammerschlag, Anke R, Kaminski, Jakob A, Karlsson, Robert, Krapohl, Eva, Lam, Max, Nygaard, Marianne, Reynolds, Chandra A, Trampush, Joey W, Young, Hannah, Zabaneh, Delilah, Hägg, Sara, Hansell, Narelle K, Karlsson, Ida K, Linnarsson, Sten, Montgomery, Grant W, Muñoz-Manchado, Ana B, Quinlan, Erin B, Schumann, Gunter, Skene, Nathan G, Webb, Bradley T, White, Tonya, Arking, Dan E, Avramopoulos, Dimitrios, Bilder, Robert M, Bitsios, Panos, Burdick, Katherine E, Cannon, Tyrone D, Chiba-Falek, Ornit, Christoforou, Andrea, Cirulli, Elizabeth T, Congdon, Eliza, Corvin, Aiden, Davies, Gail, Deary, Ian J, DeRosse, Pamela, Dickinson, Dwight, Djurovic, Srdjan, Donohoe, Gary, Conley, Emily Drabant, Eriksson, Johan G, Espeseth, Thomas, Freimer, Nelson A, Giakoumaki, Stella, Giegling, Ina, Gill, Michael, Glahn, David C, Hariri, Ahmad R, Hatzimanolis, Alex, Keller, Matthew C, Knowles, Emma, Koltai, Deborah, Konte, Bettina, Lahti, Jari, Le Hellard, Stephanie, Lencz, Todd, Liewald, David C, London, Edythe, Lundervold, Astri J, Malhotra, Anil K, Melle, Ingrid, Morris, Derek, Need, Anna C, Ollier, William, Palotie, Aarno, Payton, Antony, Pendleton, Neil, Poldrack, Russell A, Räikkönen, Katri, Reinvang, Ivar, Roussos, Panos, Rujescu, Dan, Sabb, Fred W, Scult, Matthew A, Smeland, Olav B, Smyrnis, Nikolaos, Starr, John M, Steen, Vidar M, Stefanis, Nikos C, Straub, Richard E, Sundet, Kjetil, Tiemeier, Henning, Voineskos, Aristotle N, Weinberger, Daniel R, Widen, Elisabeth, Yu, Jin, Abecasis, Goncalo, Andreassen, Ole A, Breen, Gerome, Christiansen, Lene
Publikováno v:
Nature genetics, vol 50, iss 7
Intelligence is highly heritable1 and a major determinant of human health and well-being2. Recent genome-wide meta-analyses have identified 24 genomic loci linked to variation in intelligence3-7, but much about its genetic underpinnings remains to be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::82860e64d5a6c4d94b1c261b4f60387c
https://escholarship.org/uc/item/869275xx
https://escholarship.org/uc/item/869275xx
Autor:
Lange, Leslie A, Hu, Youna, Zhang, He, Xue, Chenyi, Schmidt, Ellen M, Tang, Zheng-Zheng, Bizon, Chris, Lange, Ethan M, Smith, Joshua D, Turner, Emily H, Jun, Goo, Kang, Hyun Min, Peloso, Gina, Auer, Paul, Li, Kuo-Ping, Flannick, Jason, Zhang, Ji, Fuchsberger, Christian, Gaulton, Kyle, Lindgren, Cecilia, Locke, Adam, Manning, Alisa, Sim, Xueling, Rivas, Manuel A, Holmen, Oddgeir L, Gottesman, Omri, Lu, Yingchang, Ruderfer, Douglas, Stahl, Eli A, Duan, Qing, Li, Yun, Durda, Peter, Jiao, Shuo, Isaacs, Aaron, Hofman, Albert, Bis, Joshua C, Correa, Adolfo, Griswold, Michael E, Jakobsdottir, Johanna, Smith, Albert V, Schreiner, Pamela J, Feitosa, Mary F, Zhang, Qunyuan, Huffman, Jennifer E, Crosby, Jacy, Wassel, Christina L, Do, Ron, Franceschini, Nora, Martin, Lisa W, Robinson, Jennifer G, Assimes, Themistocles L, Crosslin, David R, Rosenthal, Elisabeth A, Tsai, Michael, Rieder, Mark J, Farlow, Deborah N, Folsom, Aaron R, Lumley, Thomas, Fox, Ervin R, Carlson, Christopher S, Peters, Ulrike, Jackson, Rebecca D, van Duijn, Cornelia M, Uitterlinden, André G, Levy, Daniel, Rotter, Jerome I, Taylor, Herman A, Gudnason, Vilmundur, Siscovick, David S, Fornage, Myriam, Borecki, Ingrid B, Hayward, Caroline, Rudan, Igor, Chen, Y Eugene, Bottinger, Erwin P, Loos, Ruth JF, Sætrom, Pål, Hveem, Kristian, Boehnke, Michael, Groop, Leif, McCarthy, Mark, Meitinger, Thomas, Ballantyne, Christie M, Gabriel, Stacey B, O'Donnell, Christopher J, Post, Wendy S, North, Kari E, Reiner, Alexander P, Boerwinkle, Eric, Psaty, Bruce M, Altshuler, David, Kathiresan, Sekar, Lin, Dan-Yu, Jarvik, Gail P, Cupples, L Adrienne, Kooperberg, Charles, Wilson, James G, Nickerson, Deborah A, Abecasis, Goncalo R, Rich, Stephen S
Publikováno v:
American journal of human genetics, vol 94, iss 2
Elevated low-density lipoprotein cholesterol (LDL-C) is a treatable, heritable risk factor for cardiovascular disease. Genome-wide association studies (GWASs) have identified 157 variants associated with lipid levels but are not well suited to assess
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______325::b0c59997ecf5a9de491aa1cfc1960172
https://escholarship.org/uc/item/3w75q2zz
https://escholarship.org/uc/item/3w75q2zz
Autor:
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Albertos, R, Perez-Tur, J, Li, R, Folkersen, L, Moltke, I, Koelling, N, Teumer, A, Kousathanas, A, Utrilla, A, Verdugo, RA, Zarate, R, Medina-Gomez, C, Gomez-Cabrero, D, Carnero-Montoro, E, Cadilla, CL, Moreno-Estrada, A, Garmendia, A, Moya, L, Sedaghati-Khayat, B, Boua, PR, Fave, M-J, Francioli, L, Lemacon, A, Migeotte, I, Patel, S, Varnai, R, Szentpeteri, JL, Sipeky, C, Colombo, F, von Hohenstaufen, K, Lio, P, Vallerga, C, Wang, Q, Tanigawa, Y, Im, H, Han, C, Song, H, Lim, J, Lee, Y, Kim, S, Im, S, Atanasovska, B, Ahmad, HF, Boer, C, Jansen, P, Franke, L, Kaja, E, Pasko, D, Kennis-Szilagyi, I, Kornilov, SA, Prijatelj, V, Prokic, I, Sivanadhan, I, Perumal, S, Esmaeeli, S, Pearson, NM, Auton, A, Shelton, JF, Shastri, AJ, Filshtein-Sonmez, T, Coker, D, Symons, A, Esparza-Gordillo, J, Aslibekyan, S, O'Connell, J, Ye, C, Weldon, CH, Perera, M, O'Leary, K, Tuck, M, O'Brien, T, Meltzer, D, O'Donnell, P, Nutescu, E, Yang, G, Alarcon, C, Herrmann, S, Mazurek, S, Banagan, J, Hamidi, Z, Barbour, A, Raffat, N, Moreno, D, Friedman, P, Ferwerda, B, van de Beek, D, Brouwer, MC, Vlaar, APJ, Wiersinga, WJ, Posthuma, D, Tissink, E, Zwinderman, AHK, Uffelmann, E, van Agtmael, M, Algera, AG, van Baarle, F, Bax, D, Beudel, M, Bogaard, HJ, Bomers, M, Bonta, PI, Bos, L, Botta, M, de Brabander, J, de Bree, G, de Bruin, S, Bugiani, M, Bulle, E, Chouchane, O, Cloherty, A, Dongelmans, D, Elbers, P, Fleuren, L, Geerlings, S, Geerts, B, Geijtenbeek, T, Girbes, A, Goorhuis, B, Grobusch, MP, Hafkamp, F, Hagens, L, Hamann, J, Harris, V, Hemke, R, Hermans, SM, Heunks, L, Hollmann, M, Horn, J, Hovius, JW, de Jong, MD, Koning, R, van Mourik, N, Nellen, J, Nossent, EJ, Paulus, F, Peters, E, van der Poll, T, Preckel, B, Prins, JM, Raasveld, J, Reijnders, T, Schinkel, M, Schultz, MJ, Schuurman, A, Sigaloff, K, Smit, M, Stijnis, CS, Stilma, W, Teunissen, C, Thoral, P, Tsonas, A, van der Valk, M, Veelo, D, de Vries, H, van Vugt, M, Wouters, D, Minnaar, RP, Kromhout, A, van Uffelen, KWJ, 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HGC, FHoGID, RegCOVID, P-PredictUs, SeroCOVID, CRiPSI, Team, GHR, Working, UCLAHATLASDM
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NATURE
Initiative, COVID H G & Dark, P 2021, ' Mapping the human genetic architecture of COVID-19. ', Nature, vol. 600, no. 7889, pp. 472-477 . https://doi.org/10.1038/s41586-021-03767-x
Nature
Nature, 600(7889), 472-477. Nature Publishing Group
Nature, vol 600, iss 7889
Nature, 600, 472-477. NATURE PORTFOLIO
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Nature, Nature Publishing Group, In press, ⟨10.1038/s41586-021-03767-x⟩
COVID-19 Host Genetics Initiative 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature, vol. 600, no. 7889, pp. 472-477 . https://doi.org/10.1038/s41586-021-03767-x
Nature, 2021, 600 (7889), pp.472-477. ⟨10.1038/s41586-021-03767-x⟩
Nature, Vol. 600, no. ²7889, p. 472-477 (2021)
472–477
Nature, vol. 600, no. 7889, pp. 472-477
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Nature, 600. Nature Publishing Group
Nature, 600, 472-477. Nature Publishing Group
Niemi, M E K, Karjalainen, J, Liao, R G, Neale, B M, Daly, M, Ganna, A, Pathak, G A, Andrews, S J, Kanai, M, Veerapen, K, Fernandez-Cadenas, I, Schulte, E C, Striano, P, Marttila, M, Minica, C, Marouli, E, Karim, M A, Wendt, F R, Savage, J, Sloofman, L, Butler-Laporte, G, Kim, H-N, Kanoni, S, Okada, Y, Byun, J, Han, Y, Uddin, M J, Smith, G D, Willer, C J, Buxbaum, J D, Karjalainen, J, Mehtonen, J, Folkersen, L, Moltke, I, Hinney, A, Wang, C, Ellinghaus, D, Brunak, S, Castro, P, Guindo-Martinez, M, Lee, J Y, Loos, R J F, Zhao, J H, Sun, Y V, Wang, B, Parker, R, Garcia, S M, Smith, O, Davis, C, COVID-19 Host Genetics Initiative, 23andMe COVID-19 Team, Norwegian SARS-CoV-2 Study Grp, Humanitas COVID-19 Task Force, Humanitas Gavazzeni COVID-19 Task, FHoGID, RegCOVID, P-PredictUs, SeroCOVID, CRiPSI, Genes & Hlth Res Team & UCLA Hlth ATLAS Data Mart Working 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature, vol. 600, pp. 472-477 . https://doi.org/10.1038/s41586-021-03767-x
Nature (Lond.) 600 (2021): 472–+. doi:10.1038/s41586-021-03767-x
info:cnr-pdr/source/autori:Mari E. K. Niemi; Juha Karjalainen; Rachel G. Liao; Benjamin M. Neale; Mark Daly; Andrea Ganna; COVID-19 Host Genetics Initiative and the GEN-COVID Multicenter Study (including Stella, Alessandra and Biscarini, Filippo)/titolo:Mapping the human genetic architecture of COVID-19/doi:10.1038%2Fs41586-021-03767-x/rivista:Nature (Lond.)/anno:2021/pagina_da:472/pagina_a:+/intervallo_pagine:472–+/volume:600
Ganna, A & Davey Smith, G 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature . https://doi.org/10.1038/s41586-021-03767-x
Nature 600, 472-477 (2021)
Baillie, J K, Wilson, J F, Bulteel, N, Hayward, C, Klaric, L, Porteous, D J, Russell, C D, Tenesa, A, Norman, L & Scott-Brown, J & Swann, O 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature . https://doi.org/10.1038/s41586-021-03767-x
Initiative, COVID H G & Dark, P 2021, ' Mapping the human genetic architecture of COVID-19. ', Nature, vol. 600, no. 7889, pp. 472-477 . https://doi.org/10.1038/s41586-021-03767-x
Nature
Nature, 600(7889), 472-477. Nature Publishing Group
Nature, vol 600, iss 7889
Nature, 600, 472-477. NATURE PORTFOLIO
Digital.CSIC. Repositorio Institucional del CSIC
instname
Nature, Nature Publishing Group, In press, ⟨10.1038/s41586-021-03767-x⟩
COVID-19 Host Genetics Initiative 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature, vol. 600, no. 7889, pp. 472-477 . https://doi.org/10.1038/s41586-021-03767-x
Nature, 2021, 600 (7889), pp.472-477. ⟨10.1038/s41586-021-03767-x⟩
Nature, Vol. 600, no. ²7889, p. 472-477 (2021)
472–477
Nature, vol. 600, no. 7889, pp. 472-477
r-IGTP. Repositorio Institucional de Producción Científica del Instituto de Investigación Germans Trias i Pujol
Digibug. Repositorio Institucional de la Universidad de Granada
Nature, 600. Nature Publishing Group
Nature, 600, 472-477. Nature Publishing Group
Niemi, M E K, Karjalainen, J, Liao, R G, Neale, B M, Daly, M, Ganna, A, Pathak, G A, Andrews, S J, Kanai, M, Veerapen, K, Fernandez-Cadenas, I, Schulte, E C, Striano, P, Marttila, M, Minica, C, Marouli, E, Karim, M A, Wendt, F R, Savage, J, Sloofman, L, Butler-Laporte, G, Kim, H-N, Kanoni, S, Okada, Y, Byun, J, Han, Y, Uddin, M J, Smith, G D, Willer, C J, Buxbaum, J D, Karjalainen, J, Mehtonen, J, Folkersen, L, Moltke, I, Hinney, A, Wang, C, Ellinghaus, D, Brunak, S, Castro, P, Guindo-Martinez, M, Lee, J Y, Loos, R J F, Zhao, J H, Sun, Y V, Wang, B, Parker, R, Garcia, S M, Smith, O, Davis, C, COVID-19 Host Genetics Initiative, 23andMe COVID-19 Team, Norwegian SARS-CoV-2 Study Grp, Humanitas COVID-19 Task Force, Humanitas Gavazzeni COVID-19 Task, FHoGID, RegCOVID, P-PredictUs, SeroCOVID, CRiPSI, Genes & Hlth Res Team & UCLA Hlth ATLAS Data Mart Working 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature, vol. 600, pp. 472-477 . https://doi.org/10.1038/s41586-021-03767-x
Nature (Lond.) 600 (2021): 472–+. doi:10.1038/s41586-021-03767-x
info:cnr-pdr/source/autori:Mari E. K. Niemi; Juha Karjalainen; Rachel G. Liao; Benjamin M. Neale; Mark Daly; Andrea Ganna; COVID-19 Host Genetics Initiative and the GEN-COVID Multicenter Study (including Stella, Alessandra and Biscarini, Filippo)/titolo:Mapping the human genetic architecture of COVID-19/doi:10.1038%2Fs41586-021-03767-x/rivista:Nature (Lond.)/anno:2021/pagina_da:472/pagina_a:+/intervallo_pagine:472–+/volume:600
Ganna, A & Davey Smith, G 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature . https://doi.org/10.1038/s41586-021-03767-x
Nature 600, 472-477 (2021)
Baillie, J K, Wilson, J F, Bulteel, N, Hayward, C, Klaric, L, Porteous, D J, Russell, C D, Tenesa, A, Norman, L & Scott-Brown, J & Swann, O 2021, ' Mapping the human genetic architecture of COVID-19 ', Nature . https://doi.org/10.1038/s41586-021-03767-x
Niemi, Mari E. K. et al. 39 páginas, figuras y tablas. Contiene material suplementario.
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors
The genetic make-up of an individual contributes to the susceptibility and response to viral infection. Although environmental, clinical and social factors
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https://explore.openaire.eu/search/publication?articleId=doi_dedup___::974d087615705cffb4d0d7bdc6394ffc
https://eprints.soton.ac.uk/456122/
https://eprints.soton.ac.uk/456122/