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pro vyhledávání: '"Albert E. Dahlberg"'
Autor:
Paul C Makosky, Albert E. Dahlberg
Publikováno v:
Biochimie. 69:885-889
Three different single base substitutions were constructed at residue C-1192 in 16S rRNA on a plasmid-coded rrnB operon of E. coli using site-directed mutagenesis. All 3 mutants conferred different levels of resistance to spectinomycin in transformed
Publikováno v:
The EMBO Journal. 8:1213-1216
Two of six mutations at a base-paired site in Escherichia coli 16S rRNA confer resistance to nine different aminoglycoside antibiotics in vivo. Chemical probing of mutant and wild-type ribosomes in the presence of paromomycin indicates that interacti