Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Eva Karamitopoulou"'
Autor:
Heather Dawson, Katharina Canonica, Viktor H. Koelzer, Eva Karamitopoulou-Diamantis, Lena Sokol, Inti Zlobec, Alessandro Lugli
Tumor-associated macrophages (TAM) play a controversial role in epithelial-mesenchymal transition (EMT) and prognosis of colorectal cancer (CRC). In particular, the microlocalization, polarization and prognostic impact of TAM in the immediate environ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3267ebb37ce3a4f30e6e524d4f81e9cb
Autor:
Alessandro Lugli, Tilman T. Rau, Eva Karamitopoulou, Inti Zlobec, Viktor H. Koelzer, Lena Sokol
Publikováno v:
Journal of Translational Medicine
Sokol, Lena; Kölzer, Viktor; Rau, Tilman; Karamitopoulou, Evanthia; Zlobec, Inti; Lugli, Alessandro (2015). Loss of tapasin correlates with diminished CD8(+) T-cell immunity and prognosis in colorectal cancer. Journal of translational medicine, 13(279), p. 279. BioMed Central 10.1186/s12967-015-0647-1
Sokol, Lena; Kölzer, Viktor; Rau, Tilman; Karamitopoulou, Evanthia; Zlobec, Inti; Lugli, Alessandro (2015). Loss of tapasin correlates with diminished CD8(+) T-cell immunity and prognosis in colorectal cancer. Journal of translational medicine, 13(279), p. 279. BioMed Central 10.1186/s12967-015-0647-1
Background Tapasin is a crucial component of the major histocompatibility (MHC) class I antigen presentation pathway. Defects in this pathway can lead to tumor immune evasion. The aim of this study was to test whether tapasin expression correlates wi
Autor:
Emilia Andersson, Giuseppe Masucci, Viktor H. Koelzer, Eva Karamitopoulou, Inti Zlobec, Heather Dawson, Alessandro Lugli
Tumor budding (single tumor cells or small tumor cell clusters) at the invasion front of colorectal cancer (CRC) is an adverse prognostic indicator linked to epithelial-mesenchymal transition. This study characterized the immunogenicity of tumor buds
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38978274a75095dcb05ec9733b544373
https://www.zora.uzh.ch/id/eprint/174562/
https://www.zora.uzh.ch/id/eprint/174562/
Autor:
Viktor H. Koelzer, Eva Karamitopoulou, Heather Dawson, José A. Galván, Marion Hädrich, Inti Zlobec, Daniel Inderbitzin, Martin D. Berger, Alessandro Lugli, Beat Schnüriger, Melina Helbling, Mario P. Tschan
Publikováno v:
Oncotarget
Galván Hernández, José Alberto; Helbling, Melina; Kölzer, Viktor; Tschan, Mario; Berger, Martin Dave; Hädrich, Marion; Schnüriger, Beat; Karamitopoulou, Evanthia; Dawson, Heather; Inderbitzin, Daniel; Lugli, Alessandro; Zlobec, Inti (2015). TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer. OncoTarget, 6(2), pp. 874-885. Impact Journals LLC 10.18632/oncotarget.2716
Scopus-Elsevier
Europe PubMed Central
Galván Hernández, José Alberto; Helbling, Melina; Kölzer, Viktor; Tschan, Mario; Berger, Martin Dave; Hädrich, Marion; Schnüriger, Beat; Karamitopoulou, Evanthia; Dawson, Heather; Inderbitzin, Daniel; Lugli, Alessandro; Zlobec, Inti (2015). TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer. OncoTarget, 6(2), pp. 874-885. Impact Journals LLC 10.18632/oncotarget.2716
Scopus-Elsevier
Europe PubMed Central
Tumor budding in colorectal cancer is likened to an epithelial-mesenchymal transition (EMT) characterized predominantly by loss of E-cadherin and up-regulation of E-cadherin repressors like TWIST1 and TWIST2. Here we investigate a possible epigenetic
Autor:
Anne C. Lukesch, Eva Karamitopoulou, Viktor H. Koelzer, Robert D. Rosenberg, Rupert Langer, Alessandro Lugli, Heather Dawson, Markus Borner, Marion Hädrich, Martin D. Berger, Makhmud Mallaev, Inti Zlobec, Daniel Inderbitzin, Ulrich Nitsche, Mario P. Tschan, Aladin Haimovici, Beat Schnüriger, Melina Helbling
Publikováno v:
Helbling, Melina; Lukesch, Anne Carolin; Haimovici, Aladin; Karamitopoulou, Evanthia; Berger, Martin Dave; Hädrich, Marion; Mallaev, Makhmud; Schnüriger, Beat; Kölzer, Viktor; Dawson, Heather; Borner, Markus; Langer, Rupert; Rosenberg, Robert; Nitsche, Ulrich; Inderbitzin, Daniel; Lugli, Alessandro; Tschan, Mario; Zlobec, Inti (2014). Investigation of IL-23 (p19, p40) and IL-23R identifies nuclear expression of IL-23 p19 as a favorable prognostic factor in colorectal cancer: a retrospective multicenter study of 675 patients. OncoTarget, 5(13), pp. 4671-4682. Impact Journals LLC
Scopus-Elsevier
Oncotarget
Scopus-Elsevier
Oncotarget
IL-23 is a heterodimeric cytokine involved in inflammatory diseases; its role in cancer progression is controversial. Here we analyse the expression of IL-23 subunits (p40 and p19) and IL-23R in colorectal cancer with regard to disease progression, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4939f0ed4a37083588b147ea6129644c
https://boris.unibe.ch/62830/1/2069-22517-4-PB.pdf
https://boris.unibe.ch/62830/1/2069-22517-4-PB.pdf
Autor:
Inti Zlobec, Daniel Inderbitzin, Sandra Grundmann, Heather Dawson, Alessandro Lugli, Eva Karamitopoulou, José A. Galván, Viktor H. Koelzer, Richard Kirsch
AIMS Tumour buds in colorectal cancer represent an aggressive subgroup of non-proliferating and non-apoptotic tumour cells. We hypothesize that the survival of tumour buds is dependent upon anoikis resistance. The role of tyrosine kinase receptor B (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12328ee9d93ce7a8877c0d7fcf9cfa8e
https://www.zora.uzh.ch/id/eprint/174572/
https://www.zora.uzh.ch/id/eprint/174572/
Autor:
Heather Dawson, Viktor H. Koelzer, Caroline Hammer, Eva Karamitopoulou, Dominique-Elisabeth Muller, Alessandro Lugli, Mary Economou, Inti Zlobec
AIMS In colorectal cancer (CRC), tumour buds represent an aggressive cell type at the invasive front with apparently low proliferation. The aim of this study was to determine proliferation and apoptotic rates of buds in comparison to tumour centre, f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4101de19170b6898d2e9f9cac5d1706e
https://www.zora.uzh.ch/id/eprint/174577/
https://www.zora.uzh.ch/id/eprint/174577/
Autor:
Giacomo Puppa, Inti Zlobec, Luigi Terracciano, Eva Karamitopoulou, Milo Horcic, Viktor H. Koelzer, Alessandro Lugli
Tumor budding is recognized by the World Health Organization as an additional prognostic factor in colorectal cancer but remains unreported in diagnostic work due to the absence of a standardized scoring method. This study aims to assess the most pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f65a4806892e6544d8de08c45f514f0a
https://www.zora.uzh.ch/id/eprint/174586/
https://www.zora.uzh.ch/id/eprint/174586/
Publikováno v:
Gastroenterology. 142:S-646
Autor:
Alessandro Lugli, Inti Zlobec, Beat Gloor, Martin Wartenberg, Aurel Perren, Viktor H. Koelzer, Eva Karamitopoulou
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Wartenberg, Martin; Zlobec, Inti; Perren, Aurel; Kölzer, Viktor; Gloor, Beat; Lugli, Alessandro; Karamitopoulou, Evanthia (2015). Accumulation of FOXP3+T-cells in the tumor microenvironment is associated with an epithelial-mesenchymal-transition-type tumor budding phenotype and is an independent prognostic factor in surgically resected pancreatic ductal adenocarcinoma. OncoTarget, 6(6), pp. 4190-4201. Impact Journals LLC
Oncotarget
Europe PubMed Central
Wartenberg, Martin; Zlobec, Inti; Perren, Aurel; Kölzer, Viktor; Gloor, Beat; Lugli, Alessandro; Karamitopoulou, Evanthia (2015). Accumulation of FOXP3+T-cells in the tumor microenvironment is associated with an epithelial-mesenchymal-transition-type tumor budding phenotype and is an independent prognostic factor in surgically resected pancreatic ductal adenocarcinoma. OncoTarget, 6(6), pp. 4190-4201. Impact Journals LLC
Oncotarget
// Martin Wartenberg 1, 2 , Inti Zlobec 2 , Aurel Perren 1, 2 , Viktor Hendrik Koelzer 1, 2 , Beat Gloor 3 , Alessandro Lugli 1, 2 , Eva Karamitopoulou 1, 2 1 Clinical Pathology Division, University of Bern, Bern, CH-3010, Switzerland 2 Translational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::540d5fe1b688cd553326f9f875c5849f
http://www.scopus.com/inward/record.url?eid=2-s2.0-84924278226&partnerID=MN8TOARS
http://www.scopus.com/inward/record.url?eid=2-s2.0-84924278226&partnerID=MN8TOARS