Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Thomas Girke"'
Autor:
Steven R. Cummings, Richard A. Miller, Daniel S. Evans, Nicholas J. Schork, Yuzhu Duan, Thomas Girke
Publikováno v:
Nucleic Acids Research
signatureSearch is an R/Bioconductor package that integrates a suite of existing and novel algorithms into an analysis environment for gene expression signature (GES) searching combined with functional enrichment analysis (FEA) and visualization meth
Autor:
Paul Shannon, Kasper D. Hansen, Sean Davis, Vincent J. Carey, Benilton S. Carvalho, Marc R. J. Carlson, Thomas Girke, Valerie Obenchain, Martin Morgan, Raphael Gottardo, Rafael A. Irizarry, Dan Tenenbaum, Hervé Pagès, Héctor Corrada Bravo, Alejandro Reyes, Michael I. Love, Robert Gentleman, James W. MacDonald, Simon Anders, Florian Hahne, Levi Waldron, Andrzej K. Oleś, Wolfgang Huber, Michael S. Lawrence, Gordon K. Smyth, Laurent Gatto
Publikováno v:
Nature Methods
Nature methods, Vol. 12, no.2, p. 115-21 (2015)
Nature methods, Vol. 12, no.2, p. 115-21 (2015)
Bioconductor is an open-source, open-development software project for the analysis and comprehension of high-throughput data in genomics and molecular biology. The project aims to enable interdisciplinary research, collaboration and rapid development
Autor:
M. Carola Zillikens, Serkalem Demissie, Yi-Hsiang Hsu, Laura M. Yerges-Armstrong, Wen-Chi Chou, Lisette Stolk, Gregory Livshits, Linda Broer, Toby Johnson, Daniel L. Koller, Zoltán Kutalik, Jian’an Luan, Ida Malkin, Janina S. Ried, Albert V. Smith, Gudmar Thorleifsson, Liesbeth Vandenput, Jing Hua Zhao, Weihua Zhang, Ali Aghdassi, Kristina Åkesson, Najaf Amin, Leslie J. Baier, Inês Barroso, David A. Bennett, Lars Bertram, Rainer Biffar, Murielle Bochud, Michael Boehnke, Ingrid B. Borecki, Aron S. Buchman, Liisa Byberg, Harry Campbell, Natalia Campos Obanda, Jane A. Cauley, Peggy M. Cawthon, Henna Cederberg, Zhao Chen, Nam H. Cho, Hyung Jin Choi, Melina Claussnitzer, Francis Collins, Steven R. Cummings, Philip L. De Jager, Ilja Demuth, Rosalie A. M. Dhonukshe-Rutten, Luda Diatchenko, Gudny Eiriksdottir, Anke W. Enneman, Mike Erdos, Johan G. Eriksson, Joel Eriksson, Karol Estrada, Daniel S. Evans, Mary F. Feitosa, Mao Fu, Melissa Garcia, Christian Gieger, Thomas Girke, Nicole L. Glazer, Harald Grallert, Jagvir Grewal, Bok-Ghee Han, Robert L. Hanson, Caroline Hayward, Albert Hofman, Eric P. Hoffman, Georg Homuth, Wen-Chi Hsueh, Monica J. Hubal, Alan Hubbard, Kim M. Huffman, Lise B. Husted, Thomas Illig, Erik Ingelsson, Till Ittermann, John-Olov Jansson, Joanne M. Jordan, Antti Jula, Magnus Karlsson, Kay-Tee Khaw, Tuomas O. Kilpeläinen, Norman Klopp, Jacqueline S. L. Kloth, Heikki A. Koistinen, William E. Kraus, Stephen Kritchevsky, Teemu Kuulasmaa, Johanna Kuusisto, Markku Laakso, Jari Lahti, Thomas Lang, Bente L. Langdahl, Lenore J. Launer, Jong-Young Lee, Markus M. Lerch, Joshua R. Lewis, Lars Lind, Cecilia Lindgren, Yongmei Liu, Tian Liu, Youfang Liu, Östen Ljunggren, Mattias Lorentzon, Robert N. Luben, William Maixner, Fiona E. McGuigan, Carolina Medina-Gomez, Thomas Meitinger, Håkan Melhus, Dan Mellström, Simon Melov, Karl Michaëlsson, Braxton D. Mitchell, Andrew P. Morris, Leif Mosekilde, Anne Newman, Carrie M. Nielson, Jeffrey R. O’Connell, Ben A. Oostra, Eric S. Orwoll, Aarno Palotie, Stephen C. J. Parker, Munro Peacock, Markus Perola, Annette Peters, Ozren Polasek, Richard L. Prince, Katri Räikkönen, Stuart H. Ralston, Samuli Ripatti, John A. Robbins, Jerome I. Rotter, Igor Rudan, Veikko Salomaa, Suzanne Satterfield, Eric E. Schadt, Sabine Schipf, Laura Scott, Joban Sehmi, Jian Shen, Chan Soo Shin, Gunnar Sigurdsson, Shad Smith, Nicole Soranzo, Alena Stančáková, Elisabeth Steinhagen-Thiessen, Elizabeth A. Streeten, Unnur Styrkarsdottir, Karin M. A. Swart, Sian-Tsung Tan, Mark A. Tarnopolsky, Patricia Thompson, Cynthia A. Thomson, Unnur Thorsteinsdottir, Emmi Tikkanen, Gregory J. Tranah, Jaakko Tuomilehto, Natasja M. van Schoor, Arjun Verma, Peter Vollenweider, Henry Völzke, Jean Wactawski-Wende, Mark Walker, Michael N. Weedon, Ryan Welch, H.-Erich Wichmann, Elisabeth Widen, Frances M. K. Williams, James F. Wilson, Nicole C. Wright, Weijia Xie, Lei Yu, Yanhua Zhou, John C. Chambers, Angela Döring, Cornelia M. van Duijn, Michael J. Econs, Vilmundur Gudnason, Jaspal S. Kooner, Bruce M. Psaty, Timothy D. Spector, Kari Stefansson, Fernando Rivadeneira, André G. Uitterlinden, Nicholas J. Wareham, Vicky Ossowski, Dawn Waterworth, Ruth J. F. Loos, David Karasik, Tamara B. Harris, Claes Ohlsson, Douglas P. Kiel
Publikováno v:
Nature Communications 8 (2017) 1
Nature Communications, Vol 8, Iss 1, Pp 1-4 (2017)
Nature Communications, 8(1)
Nature Communications
Zillikens, M C, Demissie, S, Hsu, Y-H, Yerges-Armstrong, L M, Chou, W-C, Stolk, L, Livshits, G, Broer, L, Johnson, T, Koller, D L, Kutalik, Z, Luan, J, Malkin, I, Ried, J S, Smith, A V, Thorleifsson, G, Vandenput, L, Hua Zhao, J, Zhang, W, Aghdassi, A, Åkesson, K, Amin, N, Baier, L J, Barroso, I, Bennett, D A, Bertram, L, Biffar, R, Bochud, M, Boehnke, M, Borecki, I B, Buchman, A S, Byberg, L, Campbell, H, Campos Obanda, N, Cauley, J A, Cawthon, P M, Cederberg, H, Chen, Z, Cho, N H, Jin Choi, H, Claussnitzer, M, Collins, F, Cummings, S R, de Jager, P L, Demuth, I, Dhonukshe-Rutten, R A M, Diatchenko, L, Eiriksdottir, G, Enneman, A W, Erdos, M, Eriksson, J G, Eriksson, J, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Garcia, M, Gieger, C, Girke, T, Glazer, N L, Grallert, H, Grewal, J, Han, B-G, Hanson, R L, Hayward, C, Hofman, A, Hoffman, E P, Homuth, G, Hsueh, W-C, Hubal, M J, Hubbard, A, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koistinen, H A, Kraus, W E, Kritchevsky, S, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Launer, L J, Lee, J-Y, Lerch, M M, Lewis, J R, Lind, L, Lindgren, C, Liu, Y, Liu, T, Liu, Y, Ljunggren, Ö, Lorentzon, M, Luben, R N, Maixner, W, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H K, Mellström, D, Melov, S, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Newman, A, Nielson, C M, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Parker, S C J, Peacock, M, Perola, M, Peters, A, Polasek, O, Prince, R L, Räikkönen, K, Ralston, S H, Ripatti, S, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schadt, E E, Schipf, S, Scott, L, Sehmi, J, Shen, J, Soo Shin, C, Sigurdsson, G, Smith, S, Soranzo, N, Stančáková, A, Steinhagen-Thiessen, E, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Tan, S-T, Tarnopolsky, M A, Thompson, P, Thomson, C A, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Tuomilehto, J, van Schoor, N M, Verma, A, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, Weedon, M N, Welch, R, Wichmann, H E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Xie, W, Yu, L, Zhou, Y, Chambers, J C, Döring, A, van Duijn, C M, Econs, M J, Gudnason, V, Kooner, J S, Psaty, B M, Spector, T D, Stefansson, K, Rivadeneira, F, Uitterlinden, A G, Wareham, N J, Ossowski, V, Waterworth, D, Loos, R J F, Karasik, D, Harris, T B, Ohlsson, C & Kiel, D P 2017, ' Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass ', Nature Communications, vol. 8, no. 1, pp. 1414 . https://doi.org/10.1038/s41467-017-01008-2, https://doi.org/10.1038/s41467-017-01008-2
Nature Communications, Vol 8, Iss 1, Pp 1-4 (2017)
Nature Communications, 8(1)
Nature Communications
Zillikens, M C, Demissie, S, Hsu, Y-H, Yerges-Armstrong, L M, Chou, W-C, Stolk, L, Livshits, G, Broer, L, Johnson, T, Koller, D L, Kutalik, Z, Luan, J, Malkin, I, Ried, J S, Smith, A V, Thorleifsson, G, Vandenput, L, Hua Zhao, J, Zhang, W, Aghdassi, A, Åkesson, K, Amin, N, Baier, L J, Barroso, I, Bennett, D A, Bertram, L, Biffar, R, Bochud, M, Boehnke, M, Borecki, I B, Buchman, A S, Byberg, L, Campbell, H, Campos Obanda, N, Cauley, J A, Cawthon, P M, Cederberg, H, Chen, Z, Cho, N H, Jin Choi, H, Claussnitzer, M, Collins, F, Cummings, S R, de Jager, P L, Demuth, I, Dhonukshe-Rutten, R A M, Diatchenko, L, Eiriksdottir, G, Enneman, A W, Erdos, M, Eriksson, J G, Eriksson, J, Estrada, K, Evans, D S, Feitosa, M F, Fu, M, Garcia, M, Gieger, C, Girke, T, Glazer, N L, Grallert, H, Grewal, J, Han, B-G, Hanson, R L, Hayward, C, Hofman, A, Hoffman, E P, Homuth, G, Hsueh, W-C, Hubal, M J, Hubbard, A, Huffman, K M, Husted, L B, Illig, T, Ingelsson, E, Ittermann, T, Jansson, J-O, Jordan, J M, Jula, A, Karlsson, M, Khaw, K-T, Kilpeläinen, T O, Klopp, N, Kloth, J S L, Koistinen, H A, Kraus, W E, Kritchevsky, S, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, B L, Launer, L J, Lee, J-Y, Lerch, M M, Lewis, J R, Lind, L, Lindgren, C, Liu, Y, Liu, T, Liu, Y, Ljunggren, Ö, Lorentzon, M, Luben, R N, Maixner, W, McGuigan, F E, Medina-Gomez, C, Meitinger, T, Melhus, H K, Mellström, D, Melov, S, Michaëlsson, K, Mitchell, B D, Morris, A P, Mosekilde, L, Newman, A, Nielson, C M, O'Connell, J R, Oostra, B A, Orwoll, E S, Palotie, A, Parker, S C J, Peacock, M, Perola, M, Peters, A, Polasek, O, Prince, R L, Räikkönen, K, Ralston, S H, Ripatti, S, Robbins, J A, Rotter, J I, Rudan, I, Salomaa, V, Satterfield, S, Schadt, E E, Schipf, S, Scott, L, Sehmi, J, Shen, J, Soo Shin, C, Sigurdsson, G, Smith, S, Soranzo, N, Stančáková, A, Steinhagen-Thiessen, E, Streeten, E A, Styrkarsdottir, U, Swart, K M A, Tan, S-T, Tarnopolsky, M A, Thompson, P, Thomson, C A, Thorsteinsdottir, U, Tikkanen, E, Tranah, G J, Tuomilehto, J, van Schoor, N M, Verma, A, Vollenweider, P, Völzke, H, Wactawski-Wende, J, Walker, M, Weedon, M N, Welch, R, Wichmann, H E, Widen, E, Williams, F M K, Wilson, J F, Wright, N C, Xie, W, Yu, L, Zhou, Y, Chambers, J C, Döring, A, van Duijn, C M, Econs, M J, Gudnason, V, Kooner, J S, Psaty, B M, Spector, T D, Stefansson, K, Rivadeneira, F, Uitterlinden, A G, Wareham, N J, Ossowski, V, Waterworth, D, Loos, R J F, Karasik, D, Harris, T B, Ohlsson, C & Kiel, D P 2017, ' Erratum: Large meta-analysis of genome-wide association studies identifies five loci for lean body mass ', Nature Communications, vol. 8, no. 1, pp. 1414 . https://doi.org/10.1038/s41467-017-01008-2, https://doi.org/10.1038/s41467-017-01008-2
Lean body mass, consisting mostly of skeletal muscle, is important for healthy aging. We performed a genome-wide association study for whole body (20 cohorts of European ancestry with n = 38,292) and appendicular (arms and legs) lean body mass (n = 2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c499d2b148e790bc519b0c53ad881727
https://research.wur.nl/en/publications/erratum-large-meta-analysis-of-genome-wide-association-studies-id
https://research.wur.nl/en/publications/erratum-large-meta-analysis-of-genome-wide-association-studies-id
Autor:
Suzaynn F. Schick, Prue Talbot, David C. Volz, Giovanna L. Pozuelos, Thomas Girke, Meenakshi S. Kagda
Publikováno v:
JAMA network open, vol 2, iss 6
JAMA Network Open
JAMA Network Open
Key Points Question Does acute inhalation of thirdhand smoke alter the transcriptome of the human nasal epithelium? Findings This randomized clinical trial exposed 4 healthy, nonsmoking women to clean air, which altered the expression of only 2 genes
Publikováno v:
Nucleic Acids Research
ChemMine Tools is an online service for small molecule data analysis. It provides a web interface to a set of cheminformatics and data mining tools that are useful for various analysis routines performed in chemical genomics and drug discovery. The s
Publikováno v:
Bioinformatics
Bioinformatics (Oxford, England), vol 24, iss 13
ISMB
Bioinformatics (Oxford, England), vol 24, iss 13
ISMB
Motivation: The prediction of biologically active compounds is of great importance for high-throughput screening (HTS) approaches in drug discovery and chemical genomics. Many computational methods in this area focus on measuring the structural simil
Publikováno v:
Nucleic Acids Research
RNA silencing-mediated small interfering RNAs (siRNAs) and microRNAs (miRNAs) have diverse natural roles, ranging from regulation of gene expression and heterochromatin formation to genome defense against transposons and viruses. Unlike miRNAs, endog
Publikováno v:
PLoS ONE
PloS one, vol 8, iss 10
PLoS ONE, Vol 8, Iss 10, p e77889 (2013)
PloS one, vol 8, iss 10
PLoS ONE, Vol 8, Iss 10, p e77889 (2013)
Wounding due to mechanical injury or insect feeding causes a wide array of damage to plant cells including cell disruption, desiccation, metabolite oxidation, and disruption of primary metabolism. In response, plants regulate a variety of genes and m
Autor:
Carolyn Ohno, Henrik Jönsson, Jérémy Gruel, G. Venugopala Reddy, Thomas Girke, Ram Kishor Yadav, Mariano Perales, Marcus G. Heisler
Publikováno v:
Molecular Systems Biology
The plant stem cell regulator WUSCHEL is shown to repress differentiation-promoting transcription factors. This regulatory network is analyzed with a computational model of the three-dimensional shoot stem cell niche and a combination of genetic pert
Publikováno v:
Bioinformatics
Bioinformatics (Oxford, England), vol 27, iss 18
Bioinformatics (Oxford, England), vol 27, iss 18
Motivation: Similarity clustering of next-generation sequences (NGS) is an important computational problem to study the population sizes of DNA/RNA molecules and to reduce the redundancies in NGS data. Currently, most sequence clustering algorithms a