Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Ron Stewart"'
Autor:
Matthew N. Bernstein, Mark E. Burkard, Zijian Ni, Michael Collins, Ron Stewart, Christina Kendziorski
Publikováno v:
BMC Bioinformatics, Vol 22, Iss 1, Pp 1-9 (2021)
BMC Bioinformatics
BMC Bioinformatics
Background Single-cell RNA-seq (scRNA-seq) enables the profiling of genome-wide gene expression at the single-cell level and in so doing facilitates insight into and information about cellular heterogeneity within a tissue. This is especially importa
Autor:
Michael P. Schwartz, Amy Van Aartsen, Christina Kendziorski, Cara Argus, Matthew T. Schmitz, Christopher Barry, Scott Swanson, Jared Brown, Ron Stewart, James A. Thomson, Jennifer M. Bolin, John Steill
Publikováno v:
PLoS Computational Biology
PLoS Computational Biology, Vol 17, Iss 3, p e1008778 (2021)
PLoS Computational Biology, Vol 17, Iss 3, p e1008778 (2021)
Human pluripotent stem cells hold significant promise for regenerative medicine. However, long differentiation protocols and immature characteristics of stem cell-derived cell types remain challenges to the development of many therapeutic application
Autor:
Vanessa Linke, Edna A. Trujillo, Harold A. Singer, Dain R. Brademan, Deane F. Mosher, Laura K. Muehlbauer, Qiuwen Quan, Evgenia Shishkova, Matthew N. Bernstein, Bradford S Schwartz, Ian J. Miller, Ariel Jaitovich, Jesse G. Meyer, Trenton M. Peters-Clarke, Joshua J. Coon, Scott Swanson, Amit Chopra, Hau Chieng, Brett Paulson, Katherine A. Overmyer, Yunyun Zhu, Joseph Balnis, Anupama Tiwari, Yuchen He, Marc A. Judson, Ron Stewart, Lisa A. Drake, Alejandro P. Adam, Lia R. Serrano
Publikováno v:
Cell Systems
Journal of Translational Medicine
medRxiv
article-version (status) pre
article-version (number) 1
Journal of Translational Medicine
medRxiv
article-version (status) pre
article-version (number) 1
We performed RNA-Seq and high-resolution mass spectrometry on 128 blood samples from COVID-19 positive and negative patients with diverse disease severities and outcomes. Quantified transcripts, proteins, metabolites, and lipids were associated with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::590b3e958caa102293bf216fffc2d6d4
https://doi.org/10.1101/2020.07.17.20156513
https://doi.org/10.1101/2020.07.17.20156513
Autor:
Jeyakumar Natarajan, Ian Ross, Finn Kuusisto, Kalpana Raja, James A. Thomson, Ron Stewart, John Steill
Publikováno v:
Methods in Molecular Biology ISBN: 9781493998722
Protein-Protein Interaction Networks
Protein-Protein Interaction Networks
Proteins perform their functions by interacting with other proteins. Protein-protein interaction (PPI) is critical for understanding the functions of individual proteins, the mechanisms of biological processes, and the disease mechanisms. High-throug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77dfcb2d6349942e0689423c2327bd4d
https://doi.org/10.1007/978-1-4939-9873-9_2
https://doi.org/10.1007/978-1-4939-9873-9_2
Autor:
Jinkuk Hong, Ron Stewart, Mei W. Baker, Arezoo Movaghar, David C. Page, Murray H. Brilliant, Elizabeth Berry-Kravis, Krishanu Saha, Marsha R. Mailick, Finn Kuusisto, Leann Smith DaWalt, Jan S. Greenberg
Publikováno v:
Science Advances. 5
The impact of the FMR1 premutation on human health is the subject of considerable controversy. A fundamental unanswered question is whether carrying the premutation allele is directly correlated with clinical phenotypes. A challenging problem in past
Publikováno v:
Communications Biology, Vol 2, Iss 1, Pp 1-13 (2019)
Salamanders have the remarkable ability to functionally regenerate after spinal cord transection. In response to injury, GFAP+ glial cells in the axolotl spinal cord proliferate and migrate to replace the missing neural tube and create a permissive e
Advances in single-cell transcriptomics enable measuring the gene expression of individual cells, allowing cells to be ordered by their state in a dynamic biological process. Many algorithms assign ‘pseudotimes’ to each cell, representing the pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a5fe97903c9558fe341bbb7f1e06780
Autor:
Ron Stewart, Jeff Nie, Zhonggang Hou, Nicholas E. Propson, Peng Jiang, Susanne Meyer, James A. Thomson
Publikováno v:
Cell Research
Characterization and target identification of a DNA aptamer that labels pluripotent stem cells
Autor:
Monte J. Radeke, Jeff Nie, H. Tom Soh, James A. Thomson, Seung Soo Oh, Peter J. Coffey, Michael Eisenstein, Minseon Cho, Ron Stewart
Publikováno v:
Analytical Chemistry
Affinity reagent pairs that recognize distinct epitopes on a target protein can greatly improve the sensitivity and specificity of molecular detection. Importantly, such pairs can be conjugated to generate reagents that achieve two-site “bidentate
Autor:
Scott Swanson, Jeong Hee Lee, James A. Thomson, Igor I. Slukvin, Maxim A. Vodyanik, Derek J. Theisen, Gene Uenishi, Akhilesh Kumar, Matt Raymond, Ron Stewart
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 3, Iss 6, Pp 1073-1084 (2014)
Stem Cell Reports, Vol 3, Iss 6, Pp 1073-1084 (2014)
Summary The recent identification of hemogenic endothelium (HE) in human pluripotent stem cell (hPSC) cultures presents opportunities to investigate signaling pathways that are essential for blood development from endothelium and provides an explorat